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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12321 scientific papers returned from the database with the search filters currently being used below.

Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model

Authors:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub MH, Fakhro KA
Citation:
J Cell Physiol. 2020 Jan 13. doi: 10.1002/jcp.29441. [Epub ahead of print]
Epub:
Yes
Abstract:
Myosin‐binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.29441
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub MH, Fakhro KA. Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model. J Cell Physiol. 2020 Jan 13. doi: 10.1002/jcp.29441. [Epub ahead of print].

Leucine-rich repeat containing 8A contributes to the expansion of brain ventricles in zebrafish embryos

Authors:
Tseng YT, Ko CL, Chang CT, Lee YH, Huang Fu WC, Liu IH
Citation:
Biol Open. 2020 Jan 15. pii: bio.048264. doi: 10.1242/bio.048264. [Epub ahead of print]
Epub:
Yes
Abstract:
The sodium osmotic gradient is necessary for the initiation of brain ventricle inflation, but a previous study predicted that...
Link:
https://bio.biologists.org/content/early/2020/01/08/bio.048264
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng YT, Ko CL, Chang CT, Lee YH, Huang Fu WC, Liu IH. Leucine-rich repeat containing 8A contributes to the expansion of brain ventricles in zebrafish embryos. Biol Open. 2020 Jan 15. pii: bio.048264. doi: 10.1242/bio.048264. [Epub ahead of print].

Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome

Authors:
Chiang CY, Ching YH, Chang TY, Hu LS, Yong YS, Keak PY, Mustika I, Lin MD, Liao BY
Citation:
Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020
Epub:
Not Epub
Abstract:
In the last few decades, reverse genetic and high throughput approaches have been frequently applied to the mouse (Mus musculus...
Link:
https://www.sciencedirect.com/science/article/pii/S2001037019303265
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiang CY, Ching YH, Chang TY, Hu LS, Yong YS, Keak PY, Mustika I, Lin MD, Liao BY. Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome. Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020.

Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization

Authors:
D'Orazio FM, Balwierz PJ, González AJ, Guo Y, Hernández-Rodríguez B, Wheatley L, Jasiulewicz A, Hadzhiev Y, Vaquerizas JM, Cairns B, Lenhard B, Müller F
Citation:
Dev Cell. 2021 Mar 8;56(5):641-656.e5. doi: 10.1016/j.devcel.2021.02.007. Epub 2021 Mar 1. PMID: 33651978; PMCID: PMC7957325
Epub:
Not Epub
Abstract:
In many animal models, primordial germ cell (PGC) development depends on maternally deposited germ plasm, which prevents...
Link:
https://www.cell.com/developmental-cell/pdfExtended/S1534-5807(21)00118-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
D'Orazio FM, Balwierz PJ, González AJ, Guo Y, Hernández-Rodríguez B, Wheatley L, Jasiulewicz A, Hadzhiev Y, Vaquerizas JM, Cairns B, Lenhard B, Müller F. Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization. Dev Cell. 2021 Mar 8;56(5):641-656.e5. doi: 10.1016/j.devcel.2021.02.007. Epub 2021 Mar 1. PMID: 33651978; PMCID: PMC7957325.

Functional characterization of human myosin‐binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon‐specific cardiac phenotypes in zebrafish model

Authors:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub M, Fakhro KA
Citation:
J Cellular Phys. 2020;[Epub ahead of print] doi:10.1002/jcp.29441
Epub:
Yes
Abstract:
Myosin‐binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.29441
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub M, Fakhro KA. Functional characterization of human myosin‐binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon‐specific cardiac phenotypes in zebrafish model. J Cellular Phys. 2020;[Epub ahead of print] doi:10.1002/jcp.29441.

The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels

Authors:
Greenwood IA, Stott JB
Citation:
Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573
Epub:
Not Epub
Abstract:
Within the vasculature Kv7 channels are key regulators of basal tone and contribute to a variety of receptor mediated...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2019.01573/full
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
cell culture: rat primary renal arteries
Citation Extract:
Greenwood IA, Stott JB. The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels. Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573.

Slc7a14 Is Indispensable in Zebrafish Retinas

Authors:
Zhuang YY, Xiang L, Wen XR, Shen RJ, Zhao N, Zheng SS, Han RY, Qu J, Lu F, Jin ZB
Citation:
Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019
Epub:
Not Epub
Abstract:
Previous study has identified SLC7A14 as a new causative gene of retinitis pigmentosa (RP). However, the role of SLC7A14 has...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2019.00333/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhuang YY, Xiang L, Wen XR, Shen RJ, Zhao N, Zheng SS, Han RY, Qu J, Lu F, Jin ZB. Slc7a14 Is Indispensable in Zebrafish Retinas. Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019.

Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis

Authors:
Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton RG, Dong B
Citation:
FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30
Epub:
Not Epub
Abstract:
Cell morphology and tissue integrity are essential for embryogenesis. Caveolins are membrane proteins that induce the formation...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1096/fj.201901281R
Delivery Method:
microinjection
Organism or Cell Type:
Ciona sp.
Citation Extract:
Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton RG, Dong B. Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30.

METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition

Authors:
Sui X, Hu Y, Ren C, Cao Q, Zhou S, Cao Y, Li M, Shu W, Huo R
Citation:
Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print]
Epub:
Not Epub
Abstract:
N6-methyladenosine (m6A) is the most prevalent epigenetic modification of messenger RNA (mRNA) in higher eukaryotes; this...
Link:
https://www.tandfonline.com/doi/abs/10.1080/15384101.2019.1711324
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Sui X, Hu Y, Ren C, Cao Q, Zhou S, Cao Y, Li M, Shu W, Huo R. METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition. Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print].

ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane

Authors:
Jung E, Choi TI, Lee JE, Kim CH, Kim J
Citation:
FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29
Epub:
Not Epub
Abstract:
Proteins specialized in the detection, generation, or stabilization of membrane curvature play important roles in establishing...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1096/fj.201901778R
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jung E, Choi TI, Lee JE, Kim CH, Kim J. ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane. FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29.

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