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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
Assessing intracellular pH regulation in H+-ATPase-rich ionocytes in zebrafish larvae using in vivo ratiometric imaging
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Citation:
J Exper Biol. 2020;[Epub ahead of print] doi:10.1242/jeb.212928 Epub:
Yes Abstract:
The H+-ATPase rich (HR) cells of zebrafish larvae are a sub-type of ion-transporting cell located on the yolk sac epithelium... Organism or Cell Type:
zebrafish Citation Extract: Yew HM, Zimmer AM, Perry SF. Assessing intracellular pH regulation in H+-ATPase-rich ionocytes in zebrafish larvae using in vivo ratiometric imaging. J Exper Biol. 2020;[Epub ahead of print] doi:10.1242/jeb.212928. |
Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation
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Citation:
Cell Mol Life Sci. 2020 Feb 1. doi: 10.1007/s00018-020-03465-3. [Epub ahead of print] Epub:
Yes Abstract:
Background: Small bowel vascular malformation disease (SBVM) is the most common cause of obscure gastrointestinal bleeding (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tang CT, Zhang QW, Wu S, Tang MY, Liang Q, Lin XL, Gao YJ, Ge ZZ. Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation. Cell Mol Life Sci. 2020 Feb 1. doi: 10.1007/s00018-020-03465-3. [Epub ahead of print]. |
Gjd2b-mediated gap junctions promote glutamatergic synapse formation and dendritic elaboration in Purkinje neurons
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Citation:
Elife. 2021 Aug 4;10:e68124. doi: 10.7554/eLife.68124. PMID: 34346310; PMCID: PMC8382294 Epub:
Not Epub Abstract:
Gap junctions between neurons serve as electrical synapses, in addition to conducting metabolites and signaling molecules.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sitaraman S, Yadav G, Agarwal V, Jabeen S, Verma S, Jadhav M, Thirumalai V. Gjd2b-mediated gap junctions promote glutamatergic synapse formation and dendritic elaboration in Purkinje neurons. Elife. 2021 Aug 4;10:e68124. doi: 10.7554/eLife.68124. PMID: 34346310; PMCID: PMC8382294. |
Elongator Subunit 3 (Elp3) Is Required for Zebrafish Trunk Development
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Citation:
Int J Mol Sci. 2020;21(3):925. doi:10.3390/ijms21030925 Epub:
Not Epub Abstract:
Transfer RNAs (tRNAs) are the most post-transcriptionally modified RNA species. Some of these modifications, especially the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rojas-Benítez D, Allende ML. Elongator Subunit 3 (Elp3) Is Required for Zebrafish Trunk Development. Int J Mol Sci. 2020;21(3):925. doi:10.3390/ijms21030925. |
Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs
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Citation:
J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2019.12.004 Epub:
Yes Abstract:
The CRISPR/Cas9 technology has been widely utilized for knocking out genes involved in various biological processes in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang F, Li X, He M, Ye D, Xiong F, Amin G, Zhu Z, Sun Y. Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs. J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2019.12.004. |
Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish
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Citation:
iScience. 2020 Jan 7;23(2):100817. doi: 10.1016/j.isci.2019.100817. [Epub ahead of print] Epub:
Not Epub Abstract:
Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming... Delivery Method:
injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Sharma P, Gupta S, Chaudhary M, Mitra S, Chawla B, Khursheed MA, Saran NK, Ramachandran R. Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish. iScience. 2020 Jan 7;23(2):100817. doi: 10.1016/j.isci.2019.100817. [Epub ahead of print]. |
The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development
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Citation:
J Biol Chem. 2020;295, 2724-2735. doi: 10.1074/jbc.RA119.010719. Epub:
Not Epub Abstract:
Embryonic cell fate specification and axis patterning requires integration of several signaling pathways that orchestrate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Loreti M, Shi DL, Carron C. The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development. J Biol Chem. 2020;295, 2724-2735. doi: 10.1074/jbc.RA119.010719. . |
Greb1 is required for axial elongation and segmentation in vertebrate embryos
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Citation:
Biol Open. 2020 Jan 27. pii: bio.047290. doi: 10.1242/bio.047290. [Epub ahead of print] Epub:
Yes Abstract:
During vertebrate embryonic development, the formation of axial structures is driven by a population of stem-like cells that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Prajapati RS, Mitter R, Vezzaro A, Ish-Horowicz D. Greb1 is required for axial elongation and segmentation in vertebrate embryos. Biol Open. 2020 Jan 27. pii: bio.047290. doi: 10.1242/bio.047290. [Epub ahead of print]. |
Morpholino Target Molecular Properties Affect the Swelling Process of Oligomorpholino-Functionalized Responsive Hydrogels
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Citation:
Polymers (Basel). 2020 Jan 26;12(2). pii: E268. doi: 10.3390/polym12020268 Epub:
Not Epub Abstract:
Responsive hydrogels featuring DNA as a functional unit are attracting increasing interest due to combination of versatility... Citation Extract: Parelius Jonášová E, Stokke BT. Morpholino Target Molecular Properties Affect the Swelling Process of Oligomorpholino-Functionalized Responsive Hydrogels. Polymers (Basel). 2020 Jan 26;12(2). pii: E268. doi: 10.3390/polym12020268. |
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway
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Citation:
Nat Comm. 2020;11(1):479 doi:10.1038/s41467-019-14169-z Epub:
Not Epub Abstract:
Congenital scoliosis (CS) is a complex genetic disorder characterized by vertebral malformations. The precise etiology of CS is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L. Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway. Nat Comm. 2020;11(1):479 doi:10.1038/s41467-019-14169-z. |