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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects
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Citation:
Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9 Epub:
Not Epub Abstract:
The sarco-endoplasmic reticulum (SR/ER) plays an important role in the development and progression of many heart diseases.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee S-H, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim SH, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO. REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects. Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9. |
Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits
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Citation:
EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print] Epub:
Yes Abstract:
Various species of non‐coding RNAs (ncRNAs) are enriched in specific subcellular compartments, but the mechanisms orchestrating... Delivery Method:
microinjection, electroporation Organism or Cell Type:
Xenopus laevis embryo and cell culture Citation Extract: Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto TA, Oliani E, Bridi S, Strohbuecker S, Santos-Rodriguez G, Valdembri D, Serini G, Abreu-Goodger C, Baudet ML. Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits. EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print]. |
Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube
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Citation:
Development. 2020 Dec 23;147(24):dev191494. doi: 10.1242/dev.191494. PMID: 33361092; PMCID: PMC7774892 Epub:
Not Epub Abstract:
Using the zebrafish neural tube as a model, we uncover the in vivo mechanisms allowing the generation of two opposing apical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Symonds AC, Buckley CE, Williams CA, Clarke JDW. Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube. Development. 2020 Dec 23;147(24):dev191494. doi: 10.1242/dev.191494. PMID: 33361092; PMCID: PMC7774892. |
Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]
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Citation:
Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19 Epub:
Not Epub Abstract:
Background: The unfolded protein response (UPR) is an endoplasmic reticulum pathway stimulated when the protein folding demand... Organism or Cell Type:
mouse xenograft 4T1-luciferase triple negative breast cancer cells Citation Extract: Soto-Pantoja D, Clear K, Cook KL. Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]. Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19. |
Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers
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Citation:
Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958 Epub:
Not Epub Abstract:
No abstract available. Citation Extract: Min SJ, Kim NY, Chae HY, Chun KH. Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers. Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958. |
Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development
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Citation:
Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print] Epub:
Yes Abstract:
Pharyngeal arches are derived from all three germ layers and molecular interactions among the tissue types are required for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu YH, Lin TC, Hwang SL. Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development. Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print]. |
Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo
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Citation:
J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8 Epub:
Not Epub Abstract:
BACKGROUND: The polymer-based drug/gene delivery is promising for the treatment of inherent or acquire disease, because of the... Delivery Method:
triazine-cored amphiphilic polymers (TAPs) Organism or Cell Type:
cell culture: C2C12E50 myoblast & C2C12E23 differentiated cells, mice mdx Citation Extract: Wang M, Wu B, Tucker JD, Shah SN, Lu P, Lu Q. Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo. J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8. |
Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development
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Citation:
Hepatology. 2020 Nov;72(5):1786-1799. doi: 10.1002/hep.31184 Epub:
Yes Abstract:
During liver development bipotent progenitor cells differentiate into hepatocytes and biliary epithelial cells (BECs) to ensure... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology. 2020 Nov;72(5):1786-1799. doi: 10.1002/hep.31184. |
NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models
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Citation:
PLoS Genet. 2020;16(2):e1008590. doi:10.1371/journal.pgen.1008590 Epub:
Not Epub Abstract:
The 1.6 Mbp deletion on chromosome 3q29 is associated with a range of neurodevelopmental disorders, including schizophrenia,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S. NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models. PLoS Genet. 2020;16(2):e1008590. doi:10.1371/journal.pgen.1008590. |
Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells
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Citation:
Dev Dyn. 2021 Feb;250(2):191-236. doi: 10.1002/dvdy.253. Epub 2020 Sep 26. PMID: 32940375; PMCID: PMC7891386 Epub:
Not Epub Abstract:
Background: The neural crest is a transient embryonic stem cell population. Hypoxia inducible factor (HIF)-2α is associated... Delivery Method:
injection then electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Niklasson CU, Fredlund E, Monni E, Lindvall JM, Kokaia Z, Hammarlund EU, Bronner ME, Mohlin S. Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells. Dev Dyn. 2021 Feb;250(2):191-236. doi: 10.1002/dvdy.253. Epub 2020 Sep 26. PMID: 32940375; PMCID: PMC7891386. |