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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling
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Citation:
Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z Epub:
Not Epub Abstract:
Anti-angiogenic therapies have generated significant interest for their potential to combat tumor growth. However, tumor... Delivery Method:
microinjection, Vivo-Morpholino Organism or Cell Type:
zebrafish, mice Citation Extract: Stratman AN, Farrelly OM, Mikelis CM, Miller MF, Wang Z,Pham VN, Davis AE, Burns MC, Pezoa SA, Castranova D, Yano JJ, Kilts TM, Davis GE, Gutkind JS, Weinstein BM. Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling. Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z. |
Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature
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Citation:
Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032 Epub:
Yes Abstract:
The molecular cause of the majority of rare autosomal recessive disorders remains unknown. Consanguinity due to extensive... Organism or Cell Type:
zebrafish Citation Extract: Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE. Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032. |
Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis
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Citation:
Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024 Epub:
Not Epub Abstract:
Peristalsis is indispensable for physiological function of the gut. The enteric nervous system (ENS) plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F. Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis. Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024. |
Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment
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Citation:
Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013 Epub:
Not Epub Abstract:
Histamine binds to one of the four G-protein–coupled receptors expressed by large cholangiocytes. Histamine specifically... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H. Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment. Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013. |
Cell-type specific global reprogramming of the transcriptome and epigenome in induced neurons with the 16p11.2 neuropsychiatric CNVs
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Citation:
Eur J Hum Genet. 2025 Dec;33(12):1698-1707. doi: 10.1038/s41431-025-01856-3. Epub 2025 May 15. PMID: 40374944; PMCID: PMC12341848 Epub:
Not Epub Abstract:
Copy number variants (CNVs), either deletions or duplications, at the 16p11.2 locus in the human genome are known to increase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ward TR, Qu PP, Leung LC, Zhou B, Muench KL, Khechaduri A, Plastini MJ, Charlton CA, Pattni R, Ho S, Ho M, Huang Y, Zhou P, Hallmayer JF, Mourrain P, Palmer TD, Zhang X, Urban AE. Cell-type specific global reprogramming of the transcriptome and epigenome in induced neurons with the 16p11.2 neuropsychiatric CNVs. Eur J Hum Genet. 2025 Dec;33(12):1698-1707. doi: 10.1038/s41431-025-01856-3. Epub 2025 May 15. PMID: 40374944; PMCID: PMC12341848. |
Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation
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Citation:
Development. 2021 Nov 15;148(22):dev199468. doi: 10.1242/dev.199468. Epub 2021 Nov 17. PMID: 35020873 Epub:
Not Epub Abstract:
The dynamics of multipotent neural crest cell differentiation and invasion as cells travel throughout the vertebrate embryo... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Morrison JA, McLennan R, Teddy JM, Scott AR, Kasemeier-Kulesa JC, Gogol MM, Kulesa PM. Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation. Development. 2021 Nov 15;148(22):dev199468. doi: 10.1242/dev.199468. Epub 2021 Nov 17. PMID: 35020873. |
Zebrafish miR-462-731 is required for digestive organs development
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Citation:
Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print] Epub:
Not Epub Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang Y, Huang C-X, Wang W-F, Liu H, Wang H-L. Zebrafish miR-462-731 is required for digestive organs development. Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print]. |
WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis
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Citation:
Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575 Epub:
Not Epub Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sie Z-L, Li R-Y, Sampurna PB, Hsu P-J, Liu S-C, Wang H-D, Huang C-L, Yuh C-H. WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis. Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575. |
Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy
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Citation:
Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.037 Epub:
Yes Abstract:
Myotonic dystrophy type 1 (DM1) is a multisystemic genetic disorder caused by the CTG repeat expansion in the 3′-untranslated... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HL-1 Citation Extract: Misra C, Bangru S, Lin F, Lam K, Koenig SN, Lubbers ER, Hedhli J, Murphy NP, Parker DJ, Dobrucki LW, Cooper TA, Tajkhorshid E, Mohler PJ, Kalsotra A. Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy. Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.037. |
Wip1 regulates Smad4 phosphorylation and inhibits TGF‐β signaling
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Citation:
EMBO Rep. 2020;[Epub] doi:10.15252/embr.201948693 Epub:
Yes Abstract:
The tumor suppressor Smad4, a key mediator of the TGF‐β/BMP pathways, is essential for development and tissue homeostasis.... Organism or Cell Type:
Xenopus Citation Extract: Park D-S, Yoon G-H, Kim E-Y, Lee T, Kim K, Lee PCW, Chang E-J, Choi S-C. Wip1 regulates Smad4 phosphorylation and inhibits TGF‐β signaling. EMBO Rep. 2020;[Epub] doi:10.15252/embr.201948693. |