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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12420 scientific papers returned from the database with the search filters currently being used below.
There are 12420 scientific papers returned from the database with the search filters currently being used below.
Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice
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Citation:
J Pathol. 2019 Mar 18. doi: 10.1002/path.5263. [Epub ahead of print] Epub:
Not Epub Abstract:
Exon skipping is a promising genetic therapeutic strategy for restoring dystrophin expression in the treatment of Duchenne... Organism or Cell Type:
mice mdx Citation Extract: Vila MC, Novak JS, Benny Klimek M, Li N, Morales M, Fritz AG, Edwards K, Boehler JF, Hogarth MW, Kinder TB, Zhang A, Mazala D, Fiorillo AA, Douglas B, Chen YW, van den Anker J, Lu QL, Hathout Y, Hoffman EP, Partridge TA, Nagaraju K. Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice. J Pathol. 2019 Mar 18. doi: 10.1002/path.5263. [Epub ahead of print]. |
Thrombocyte inhibition restores protective immunity to mycobacterial infection in zebrafish
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Citation:
J Infect Dis. 2019 Mar 16. pii: jiz110. doi: 10.1093/infdis/jiz110. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Infection-induced thrombocytosis is a clinically important complication of tuberculosis infection. Recent studies... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hortle E, Johnson KE, Johansen MD, Nguyen T, Shavit JA, Britton WJ, Tobin DM, Oehlers SH. Thrombocyte inhibition restores protective immunity to mycobacterial infection in zebrafish. J Infect Dis. 2019 Mar 16. pii: jiz110. doi: 10.1093/infdis/jiz110. [Epub ahead of print]. |
Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk
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Citation:
Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18 Epub:
Not Epub Abstract:
. . .
There is an unmet need for the treatment of glioblastoma multiforme (GBM). The extracellular matrix, including... Delivery Method:
nanoparticles Organism or Cell Type:
mice with glioblastome xenograft Citation Extract: Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY. Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk. Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18. |
A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development
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Citation:
Cell Molec Life Sci. 2019;[Epub] doi:10.1007/s00018-019-03067-8 Epub:
Yes Abstract:
The respiratory epithelium arises from alveolar epithelial progenitors which differentiate into alveolar epithelial type 1 (AT1... Organism or Cell Type:
lung explants Citation Extract: Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Susanne Herold S, Cordero J, Singh I, Jochen Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Jin-San Zhang J-S, Chao C-M, Bellusci S. A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cell Molec Life Sci. 2019;[Epub] doi:10.1007/s00018-019-03067-8. |
Zebrafish Model for Non-Syndromic X-linked Sensorineural Deafness, DFNX1
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Citation:
Anat Rec (Hoboken). 2019 Mar 15. doi: 10.1002/ar.24115. [Epub ahead of print] Epub:
Yes Abstract:
Hereditary deafness is often a neurosensory disorder and affects the quality of life of humans. Only three X-linked genes (POU... Organism or Cell Type:
zebrafish Citation Extract: DeSmidt AA, Zou B, Grati M, Yan D, Mittal R, Yao Q, Richmond MT, Denyer S, Liu XZ, Lu Z. Zebrafish Model for Non-Syndromic X-linked Sensorineural Deafness, DFNX1. Anat Rec (Hoboken). 2019 Mar 15. doi: 10.1002/ar.24115. [Epub ahead of print]. |
cMet signaling functions during zebrafish hindbrain development
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Citation:
Dev Biol. 2008;329(2):541. doi:10.1016/j.ydbio.2008.05.270 Epub:
Not Epub Abstract:
During development, cMet signaling regulates a range of cellular processes, including growth, survival and migration (... Organism or Cell Type:
zebrafish Citation Extract: Elsen GE, Choi LY, Prince VE, Ho RK. cMet signaling functions during zebrafish hindbrain development. Dev Biol. 2008;329(2):541. doi:10.1016/j.ydbio.2008.05.270. |
Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue
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Citation:
Curr Biol. 2021 Aug 9;31(15):3409-3418.e6. doi: 10.1016/j.cub.2021.05.023. Epub 2021 Jun 9. PMID: 34111402; PMCID: PMC8360906 Epub:
Not Epub Abstract:
Epithelial tissues are highly sensitive to anisotropies in mechanical force, with cells altering fundamental behaviors, such as... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Moruzzi M, Nestor-Bergmann A, Goddard GK, Tarannum N, Brennan K, Woolner S. Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue. Curr Biol. 2021 Aug 9;31(15):3409-3418.e6. doi: 10.1016/j.cub.2021.05.023. Epub 2021 Jun 9. PMID: 34111402; PMCID: PMC8360906. |
A Smart Imaging Workflow for Organ-Specific Screening in a Cystic Kidney Zebrafish Disease Model
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Citation:
Int J Med Sci. 2019;20(6):1290. doi:10.3390/ijms20061290 Epub:
Not Epub Abstract:
The zebrafish is being increasingly used in biomedical research and drug discovery to conduct large-scale compound screening.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pandey G, Westhoff JH, Schaefer F, Gehrig L. A Smart Imaging Workflow for Organ-Specific Screening in a Cystic Kidney Zebrafish Disease Model. Int J Med Sci. 2019;20(6):1290. doi:10.3390/ijms20061290. |
FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae)
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Citation:
Dev Dyn. 2019 Mar 11. doi: 10.1002/dvdy.25. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Fox genes are a large family of transcription factors that play diverse roles in the immune system, metabolism,... Organism or Cell Type:
Xenopus laevis Citation Extract: Naumann B, Schmidt J, Olsson L. FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae). Dev Dyn. 2019 Mar 11. doi: 10.1002/dvdy.25. [Epub ahead of print]. |
The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1
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Citation:
Front Physiol. 2019 Feb 25;10:134. doi: 10.3389/fphys.2019.00134. eCollection 2019 Epub:
Not Epub Abstract:
Joubert syndrome (JS) is a congenital autosomal-recessive or-in rare cases-X-linked inherited disease. The diagnostic hallmark... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM. The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1. Front Physiol. 2019 Feb 25;10:134. doi: 10.3389/fphys.2019.00134. eCollection 2019. |