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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12420 scientific papers returned from the database with the search filters currently being used below.

Regional Gene Expression Profile Comparison Reveals the Unique Transcriptome of the Optic Fissure

Authors:
Cao M, Ouyang J, Liang H, Guo J, Lin S, Yang S, Xie T, Chen S
Citation:
Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):5773-5784. doi: 10.1167/iovs.18-23962
Epub:
Not Epub
Abstract:
Purpose: The optic fissure (OF) is a transient opening in the ventral optic cup (OC) that acts as a passage for blood vessels...
Link:
https://iovs.arvojournals.org/article.aspx?articleid=2718275
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cao M, Ouyang J, Liang H, Guo J, Lin S, Yang S, Xie T, Chen S. Regional Gene Expression Profile Comparison Reveals the Unique Transcriptome of the Optic Fissure. Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):5773-5784. doi: 10.1167/iovs.18-23962.

Inhibition of dengue virus replication in monocyte-derived dendritic cells by vivo-morpholino oligomers

Authors:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus PT
Citation:
Virus Res. 2019 Jan 15;260:123-128. doi: 10.1016/j.virusres.2018.11.014. Epub 2018 Nov 29. PMID: 30503719
Epub:
Yes
Abstract:
Skin dendritic cells (DCs) are primary target cells of dengue virus (DENV) infection and they play an important role in its...
Link:
https://linkinghub.elsevier.com/retrieve/pii/S0168-1702(18)30380-0
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: human monocyte-derived dendritic cells (MDDC)
Citation Extract:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus PT. Inhibition of dengue virus replication in monocyte-derived dendritic cells by vivo-morpholino oligomers. Virus Res. 2019 Jan 15;260:123-128. doi: 10.1016/j.virusres.2018.11.014. Epub 2018 Nov 29. PMID: 30503719.

Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development

Authors:
Kim Y, Jeong Y, Kwon K, Ismail T, Lee H-K, Kim C, Park J-W, Kwon O-S, Kang B-S, Lee D-S, Park TJ, Kwon T, Lee H-S
Citation:
Epigenet & Chromatin. 2018;11:72 doi:10.1186/s13072-018-0241-x
Epub:
Not Epub
Abstract:
Background: Lysine-specific histone demethylase 5C (KDM5C) belongs to the jumonji family of demethylases and is specific for...
Link:
https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-018-0241-x
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kim Y, Jeong Y, Kwon K, Ismail T, Lee H-K, Kim C, Park J-W, Kwon O-S, Kang B-S, Lee D-S, Park TJ, Kwon T, Lee H-S. Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development. Epigenet & Chromatin. 2018;11:72 doi:10.1186/s13072-018-0241-x.

Fer1l6 Is Essential for the Development of Vertebrate Muscle Tissue in Zebrafish

Authors:
Bonventre JA, Holman C, Manchanda A, Codding SJ, Chau T, Huegel J, Barton C, Tanguay R, Johnson CP
Citation:
Mol Biol Cell. 2018 Dec 5:mbcE18060401. doi: 10.1091/mbc.E18-06-0401. [Epub ahead of print]
Epub:
Yes
Abstract:
The precise spatial and temporal expression of genes is essential for proper organismal development. Despite their importance...
Link:
https://www.molbiolcell.org/doi/abs/10.1091/mbc.E18-06-0401
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bonventre JA, Holman C, Manchanda A, Codding SJ, Chau T, Huegel J, Barton C, Tanguay R, Johnson CP. Fer1l6 Is Essential for the Development of Vertebrate Muscle Tissue in Zebrafish. Mol Biol Cell. 2018 Dec 5:mbcE18060401. doi: 10.1091/mbc.E18-06-0401. [Epub ahead of print].

Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy

Authors:
Jirka C, Pak JH, Grosgogeat CA, Marchetii MM, Gupta VA
Citation:
Hum Mol Genet. 2019 Aug 1;28(15):2549-2560. doi: 10.1093/hmg/ddz078. PMID: 30986853; PMCID: PMC6644164
Epub:
Not Epub
Abstract:
Nemaline myopathy (NM) is the most common form of congenital myopathy that results in hypotonia and muscle weakness. This...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6644164/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jirka C, Pak JH, Grosgogeat CA, Marchetii MM, Gupta VA. Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy. Hum Mol Genet. 2019 Aug 1;28(15):2549-2560. doi: 10.1093/hmg/ddz078. PMID: 30986853; PMCID: PMC6644164.

Tfap2a is a novel gatekeeper of nephron differentiation during kidney development

Authors:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA
Citation:
Development. 2019 Jul 10;146(13):dev172387. doi: 10.1242/dev.172387. PMID: 31160420; PMCID: PMC6633607
Epub:
Yes
Abstract:
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6633607/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development. 2019 Jul 10;146(13):dev172387. doi: 10.1242/dev.172387. PMID: 31160420; PMCID: PMC6633607.

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish

Authors:
Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch KP, Lillesaar C
Citation:
Biol Open. 2019 Jun 5;8(6):bio040683. doi: 10.1242/bio.040683. PMID: 31036752; PMCID: PMC6602327
Epub:
Yes
Abstract:
In most vertebrates, including zebrafish, the hypothalamic serotonergic cerebrospinal fluid-contacting (CSF-c) cells constitute...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6602327/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch KP, Lillesaar C. Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish. Biol Open. 2019 Jun 5;8(6):bio040683. doi: 10.1242/bio.040683. PMID: 31036752; PMCID: PMC6602327.

Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects

Authors:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL
Citation:
Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are highly conserved, small non-coding RNAs that regulate gene expressions by binding to the 3'...
Link:
http://dev.biologists.org/content/145/23/dev167130
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL. Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects. Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print].

Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43

Authors:
Bhattacharya S, Gargiulo D, Iovine MK
Citation:
Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975
Epub:
Yes
Abstract:
The correct positioning of joints in the vertebrate skeleton is not well understood. Mutations in connexin43 (cx43) cause the...
Link:
http://dev.biologists.org/content/145/23/dev166975
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhattacharya S, Gargiulo D, Iovine MK. Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43. Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975.

The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis

Authors:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W
Citation:
Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background and aims: It has been well established that ezetimibe blocks cholesterol absorption to prevent the negative effects...
Link:
https://www.sciencedirect.com/science/article/pii/S0021915018314710
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W. The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print].

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