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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12420 scientific papers returned from the database with the search filters currently being used below.

Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations

Authors:
Choi JP, Wang R, Yang X, Wang X, Wang L, Ting KK, Foley M, Cogger V, Yang Z, Liu F, Han Z, Liu R, Baell J, Zheng X
Citation:
Sci Adv. 2018 Nov 7;4(11):eaau0731. doi: 10.1126/sciadv.aau0731. eCollection 2018 Nov
Epub:
Not Epub
Abstract:
Cerebral cavernous malformation (CCM) is a common cerebrovascular disease that can occur sporadically or be inherited. They are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choi JP, Wang R, Yang X, Wang X, Wang L, Ting KK, Foley M, Cogger V, Yang Z, Liu F, Han Z, Liu R, Baell J, Zheng X. Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations. Sci Adv. 2018 Nov 7;4(11):eaau0731. doi: 10.1126/sciadv.aau0731. eCollection 2018 Nov.

Growth Cone Tctp Is Dynamically Regulated by Guidance Cues

Authors:
Roque CG, Holt CE
Citation:
Front Mol Neurosci. 2018;[Epub] doi:10.3389/fnmol.2018.00399
Epub:
Not Epub
Abstract:
Translationally controlled tumor protein (Tctp) contributes to retinal circuitry formation by promoting axon growth and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Roque CG, Holt CE. Growth Cone Tctp Is Dynamically Regulated by Guidance Cues. Front Mol Neurosci. 2018;[Epub] doi:10.3389/fnmol.2018.00399.

Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo

Authors:
Bharathan NK, Dickinson AJG
Citation:
Dev Biol. 2019 Jun 15;450(2):115-131. doi: 10.1016/j.ydbio.2019.03.010. Epub 2019 Mar 29. PMID: 30935896; PMCID: PMC6659752
Epub:
Not Epub
Abstract:
Desmoplakin (Dsp) is a unique and critical desmosomal protein, that is integral to epidermal development. However, it is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bharathan NK, Dickinson AJG. Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo. Dev Biol. 2019 Jun 15;450(2):115-131. doi: 10.1016/j.ydbio.2019.03.010. Epub 2019 Mar 29. PMID: 30935896; PMCID: PMC6659752.

New Neuronal Subtypes With a "Pre-Pancreatic" Signature in the Sea Urchin Stongylocentrotus purpuratus

Authors:
Perillo M, Paganos P, Mattiello T, Cocurullo M, Oliveri P, Arnone MI
Citation:
Front Endocrinol. 2018;[Epub] doi:10.3389/fendo.2018.00650
Epub:
Yes
Abstract:
Neurons and pancreatic endocrine cells have a common physiology and express a similar toolkit of transcription factors during...
Delivery Method:
microinjection
Organism or Cell Type:
Stongylocentroatus purpuratus (sea urchin)
Citation Extract:
Perillo M, Paganos P, Mattiello T, Cocurullo M, Oliveri P, Arnone MI. New Neuronal Subtypes With a "Pre-Pancreatic" Signature in the Sea Urchin Stongylocentrotus purpuratus. Front Endocrinol. 2018;[Epub] doi:10.3389/fendo.2018.00650.

Transcriptome analysis of Xenopus orofacial tissues deficient in retinoic acid receptor function

Authors:
Wahl SE, Wyatt BH, Turner SD, Dickinson AJG
Citation:
BMC Genomics. 2018 Nov 3;19(1):795. doi: 10.1186/s12864-018-5186-8
Epub:
Not Epub
Abstract:
BACKGROUND: Development of the face and mouth is orchestrated by a large number of transcription factors, signaling pathways...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wahl SE, Wyatt BH, Turner SD, Dickinson AJG. Transcriptome analysis of Xenopus orofacial tissues deficient in retinoic acid receptor function. BMC Genomics. 2018 Nov 3;19(1):795. doi: 10.1186/s12864-018-5186-8.

rf2 Regulates the Hepatoprotective Effects of Remote Ischemic Conditioning in Hemorrhagic Shock

Authors:
Leung CH, Caldarone CA, Guan R, Wen XY, Ailenberg M, Kapus A, Szaszi K, Rotstein OD
Citation:
Antioxid Redox Signal. 2018 Nov 7. doi: 10.1089/ars.2018.7541. [Epub ahead of print]
Epub:
Not Epub
Abstract:
AIMS: Remote ischemic conditioning (RIC) protects against organ ischemia/reperfusion injury in experimental and clinical...
Organism or Cell Type:
zebrafish
Citation Extract:
Leung CH, Caldarone CA, Guan R, Wen XY, Ailenberg M, Kapus A, Szaszi K, Rotstein OD. rf2 Regulates the Hepatoprotective Effects of Remote Ischemic Conditioning in Hemorrhagic Shock. Antioxid Redox Signal. 2018 Nov 7. doi: 10.1089/ars.2018.7541. [Epub ahead of print].

Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA ( slincR) Using the Zebrafish Model

Authors:
Garcia GR, Shankar P, Dunham CL, Garcia A, La Du JK, Truong L, Tilton SC, Tanguay RL
Citation:
Environ Health Perspect. 2018 Nov;126(11):117002. doi: 10.1289/EHP3281
Epub:
Not Epub
Abstract:
BACKGROUND: A structurally diverse group of chemicals, including dioxins [e.g., 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)]...
Citation Extract:
Garcia GR, Shankar P, Dunham CL, Garcia A, La Du JK, Truong L, Tilton SC, Tanguay RL. Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA ( slincR) Using the Zebrafish Model. Environ Health Perspect. 2018 Nov;126(11):117002. doi: 10.1289/EHP3281.

Phosphorylation of ELAVL1 (Ser219/Ser316) mediated by PKC is required for erythropoiesis

Authors:
Zhou X, Wang S, Zheng M, Kuver A, Wan X, Dai K, Li X
Citation:
Biochim Biophys Acta Mol Cell Res. 2018 Nov 2. pii: S0167-4889(18)30494-4. doi: 10.1016/j.bbamcr.2018.10.021. [Epub ahead of print]
Epub:
Yes
Abstract:
Elavl1 (also known as HuR), an RNA binding protein highly conserved between zebrafish and human, regulates gene expression by...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou X, Wang S, Zheng M, Kuver A, Wan X, Dai K, Li X. Phosphorylation of ELAVL1 (Ser219/Ser316) mediated by PKC is required for erythropoiesis. Biochim Biophys Acta Mol Cell Res. 2018 Nov 2. pii: S0167-4889(18)30494-4. doi: 10.1016/j.bbamcr.2018.10.021. [Epub ahead of print].

Quantification of glioblastoma progression in zebrafish xenografts: Adhesion to laminin alpha 5 promotes glioblastoma microtumor formation and inhibits cell invasion

Authors:
Gamble JT, Reed-Harris Y, Barton CL, La Du J, Tanguay R, Greenwood JA
Citation:
Biochem Biophys Res Commun. 2018 Oct 30. pii: S0006-291X(18)32232-0. doi: 10.1016/j.bbrc.2018.10.076. [Epub ahead of print]
Epub:
Yes
Abstract:
Glioblastoma (GBM) is a deadly disease due to its ability to quickly invade and destroy brain tissue. Slowing or stopping GBM...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gamble JT, Reed-Harris Y, Barton CL, La Du J, Tanguay R, Greenwood JA. Quantification of glioblastoma progression in zebrafish xenografts: Adhesion to laminin alpha 5 promotes glioblastoma microtumor formation and inhibits cell invasion. Biochem Biophys Res Commun. 2018 Oct 30. pii: S0006-291X(18)32232-0. doi: 10.1016/j.bbrc.2018.10.076. [Epub ahead of print].

NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy

Authors:
Watanabe N, Nagata T, Satou Y, Masuda S, Saito T, Kitagawa H, Komaki H, Takagaki K, Takeda S
Citation:
Mol Ther Nucleic Acids. 2018 Sep 27;13:442-449. doi: 10.1016/j.omtn.2018.09.017. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD), the most common lethal heritable childhood disease, is caused by mutations in the DMD gene...
Delivery Method:
electroporation, Endo-Porter
Organism or Cell Type:
cell culture: RD cells, primary DMD fibroblasts
Citation Extract:
Watanabe N, Nagata T, Satou Y, Masuda S, Saito T, Kitagawa H, Komaki H, Takagaki K, Takeda S. NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids. 2018 Sep 27;13:442-449. doi: 10.1016/j.omtn.2018.09.017. [Epub ahead of print].

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