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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12221 scientific papers returned from the database with the search filters currently being used below.

Jak2 and Jaw Muscles Are Required for Buccopharyngeal Membrane Perforation during Mouth Development

Authors:
Dickinson AJG
Citation:
J Dev Biol. 2023 May 31;11(2):24. doi: 10.3390/jdb11020024
Epub:
Not Epub
Abstract:
The mouth is a central feature of our face, without which we could not eat, breathe, or communicate. A critical and early event...
Link:
https://www.mdpi.com/2221-3759/11/2/24
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Dickinson AJG. Jak2 and Jaw Muscles Are Required for Buccopharyngeal Membrane Perforation during Mouth Development. J Dev Biol. 2023 May 31;11(2):24. doi: 10.3390/jdb11020024.

Directionality of developing skeletal muscles is set by mechanical forces

Authors:
Sunadome K, Erickson AG, Kah D, Fabry B, Adori C, Kameneva P, Faure L, Kanatani S, Kaucka M, Dehnisch Ellström I, Tesarova M, Zikmund T, Kaiser J, Edwards S, Maki K, Adachi T, Yamamoto T, Fried K, Adameyko I
Citation:
Nat Commun. 2023 May 27;14(1):3060. doi: 10.1038/s41467-023-38647-7
Epub:
Not Epub
Abstract:
Formation of oriented myofibrils is a key event in musculoskeletal development. However, the mechanisms that drive myocyte...
Link:
https://www.nature.com/articles/s41467-023-38647-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sunadome K, Erickson AG, Kah D, Fabry B, Adori C, Kameneva P, Faure L, Kanatani S, Kaucka M, Dehnisch Ellström I, Tesarova M, Zikmund T, Kaiser J, Edwards S, Maki K, Adachi T, Yamamoto T, Fried K, Adameyko I. Directionality of developing skeletal muscles is set by mechanical forces. Nat Commun. 2023 May 27;14(1):3060. doi: 10.1038/s41467-023-38647-7.

Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis

Authors:
Wesselman HM, Flores-Mireles AL, Bauer A, Pei L, Wingert RA
Citation:
Development. 2023 May 15;150(10):dev201411. doi: 10.1242/dev.201411. Epub 2023 May 26
Epub:
Not Epub
Abstract:
Cilia are essential for the ontogeny and function of many tissues, including the kidney. Here, we report that transcription...
Link:
https://journals.biologists.com/dev/article/150/10/dev201411/310753/Esrr-a-regulates-nephron-and-ciliary-development
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wesselman HM, Flores-Mireles AL, Bauer A, Pei L, Wingert RA. Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis. Development. 2023 May 15;150(10):dev201411. doi: 10.1242/dev.201411. Epub 2023 May 26.

Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2

Authors:
Bieder A, Chandrasekar G, Wason A, Erkelenz S, Gopalakrishnan J, Kere J, Tapia-Páez I
Citation:
BMC Mol Cell Biol. 2023 May 26;24(1):20. doi: 10.1186/s12860-023-00483-4
Epub:
Not Epub
Abstract:
Background: DYX1C1 (DNAAF4) and DCDC2 are two of the most replicated dyslexia candidate genes in genetic studies. They both...
Link:
https://bmcmolcellbiol.biomedcentral.com/articles/10.1186/s12860-023-00483-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bieder A, Chandrasekar G, Wason A, Erkelenz S, Gopalakrishnan J, Kere J, Tapia-Páez I. Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2. BMC Mol Cell Biol. 2023 May 26;24(1):20. doi: 10.1186/s12860-023-00483-4.

Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation

Authors:
Wang H, Zaiser F, Eckert P, Ruf J, Kayser N, Veenstra AC, Müller M, Haas R, Walz G, Yakulov TA
Citation:
Biochem Biophys Res Commun. 2023 Jun 19;673:9-15. doi: 10.1016/j.bbrc.2023.06.058. Online ahead of print
Epub:
Not Epub
Abstract:
Nephronophthisis (NPH), an autosomal recessive ciliopathy, results from mutations in more than 20 different genes (NPHPs)....
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X23008136
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang H, Zaiser F, Eckert P, Ruf J, Kayser N, Veenstra AC, Müller M, Haas R, Walz G, Yakulov TA. Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation. Biochem Biophys Res Commun. 2023 Jun 19;673:9-15. doi: 10.1016/j.bbrc.2023.06.058. Online ahead of print.

Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription

Authors:
Shih HY, Chen HY, Huang YC, Yeh TH, Chen YC, Cheng YC
Citation:
Stem Cells Dev. 2023 Jun 26. doi: 10.1089/scd.2023.0005. Online ahead of print
Epub:
Yes
Abstract:
Neural progenitor cells are self-renewable, proliferative, and multipotent cell populations that generate diverse types of...
Link:
https://www.liebertpub.com/doi/10.1089/scd.2023.0005
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shih HY, Chen HY, Huang YC, Yeh TH, Chen YC, Cheng YC. Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription. Stem Cells Dev. 2023 Jun 26. doi: 10.1089/scd.2023.0005. Online ahead of print.

A median fin derived from the lateral plate mesoderm and the origin of paired fins

Authors:
Tzung KW, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K, Tomecka MJ, Zhang C, Brombacher EC, White WT, Roehl HH, Tulenko FJ, Winkler C, Currie PD, Amaya E, Davis MC, Bronner ME, Mosimann C, Carney TJ
Citation:
Nature. 2023 Jun;618(7965):543-549. doi:10.1038/s41586-023-06100-w. Epub 2023 May 24
Epub:
Not Epub
Abstract:
The development of paired appendages was a key innovation during evolution and facilitated the aquatic to terrestrial...
Link:
https://www.nature.com/articles/s41586-023-06100-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tzung KW, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K, Tomecka MJ, Zhang C, Brombacher EC, White WT, Roehl HH, Tulenko FJ, Winkler C, Currie PD, Amaya E, Davis MC, Bronner ME, Mosimann C, Carney TJ. A median fin derived from the lateral plate mesoderm and the origin of paired fins . Nature. 2023 Jun;618(7965):543-549. doi:10.1038/s41586-023-06100-w. Epub 2023 May 24.

Cerebellar granular neuron progenitors exit their germinative niche via BarH-like1 activity mediated partly by inhibition of T-cell factor

Authors:
Bou-Rouphael J, Doulazmi M, Eschstruth A, Abdou A, Durand BC
Citation:
Development. 2024 Jul 1;151(13):dev202234. doi: 10.1242/dev.202234. Epub 2024 Jul 10. PMID: 38860486
Epub:
Not Epub
Abstract:
Cerebellar granule neuron progenitors (GNPs) originate from the upper rhombic lip (URL), a germinative niche in which...
Link:
https://journals.biologists.com/dev/article/151/13/dev202234/359782/Cerebellar-granular-neuron-progenitors-exit-their
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis
Citation Extract:
Bou-Rouphael J, Doulazmi M, Eschstruth A, Abdou A, Durand BC. Cerebellar granular neuron progenitors exit their germinative niche via BarH-like1 activity mediated partly by inhibition of T-cell factor. Development. 2024 Jul 1;151(13):dev202234. doi: 10.1242/dev.202234. Epub 2024 Jul 10. PMID: 38860486.

Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction

Authors:
Alvizi L, Nani D, Brito LA, Kobayashi GS, Passos-Bueno MR, Mayor R
Citation:
Nat Commun. 2023 May 24;14(1):2868. doi: 10.1038/s41467-023-38526-1
Epub:
Not Epub
Abstract:
Gene-environment interactions are believed to play a role in multifactorial phenotypes, although poorly described...
Link:
https://www.nature.com/articles/s41467-023-38526-1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Alvizi L, Nani D, Brito LA, Kobayashi GS, Passos-Bueno MR, Mayor R. Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction. Nat Commun. 2023 May 24;14(1):2868. doi: 10.1038/s41467-023-38526-1.

Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network

Authors:
Letelier J, Buono L, Almuedo-Castillo M, Zang J, Mounieres C, González-Díaz S, Polvillo R, Sanabria-Reinoso E, Corbacho J, Sousa-Ortega A, Diez Del Corral R, Neuhauss SCF, Martínez-Morales JR
Citation:
Elife. 2023 May 25;12:e85594. doi: 10.7554/eLife.85594
Epub:
Not Epub
Abstract:
Genetic studies in human and mice have established a dual role for Vsx genes in retina development: an early function in...
Link:
https://elifesciences.org/articles/85594
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Letelier J, Buono L, Almuedo-Castillo M, Zang J, Mounieres C, González-Díaz S, Polvillo R, Sanabria-Reinoso E, Corbacho J, Sousa-Ortega A, Diez Del Corral R, Neuhauss SCF, Martínez-Morales JR. Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network. Elife. 2023 May 25;12:e85594. doi: 10.7554/eLife.85594.

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