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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo
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Citation:
Front Synaptic Neurosci. 2023 May 12;15:1176864. doi: 10.3389/fnsyn.2023.1176864. eCollection 2023 Epub:
Not Epub Abstract:
Cannabis exposure during gestation evokes significant molecular modifications to neurodevelopmental programs leading to... Delivery Method:
electroporation Organism or Cell Type:
Xenopus laevis tadpoles Citation Extract: Del Rio R Jr, Serrano RG, Gomez E, Martinez JC, Edward MA, Santos RA, Diaz KS, Cohen-Cory S. Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo. Front Synaptic Neurosci. 2023 May 12;15:1176864. doi: 10.3389/fnsyn.2023.1176864. eCollection 2023. |
The U1 antisense morpholino oligonucleotide (AMO) disrupts U1 snRNP structure to promote intronic PCPA modification of pre-mRNAs
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Citation:
J Biol Chem. 2023 May 22:104854. doi: 10.1016/j.jbc.2023.104854. Online ahead of print Epub:
Yes Abstract:
Functional depletion of the U1 small nuclear ribonucleoprotein (snRNP) with a 25 nt U1 AMO (antisense morpholino... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Feng Q, Lin Z, Deng Y, Ran Y, Yu R, Xiang AP, Ye C, Yao C. The U1 antisense morpholino oligonucleotide (AMO) disrupts U1 snRNP structure to promote intronic PCPA modification of pre-mRNAs. J Biol Chem. 2023 May 22:104854. doi: 10.1016/j.jbc.2023.104854. Online ahead of print. |
Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway
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Citation:
Front Cell Dev Biol. 2023 Apr 4;11:1123299. doi: 10.3389/fcell.2023.1123299. eCollection 2023 Epub:
Not Epub Abstract:
Objective: Cartilage, as the majority of adult mammalian tissues, has limited regeneration capacity. Cartilage degradation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sapède D, Bahraoui S, Abou Nassif L, Barthelaix A, Mathieu M, Jorgensen C, Djouad F. Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway. Front Cell Dev Biol. 2023 Apr 4;11:1123299. doi: 10.3389/fcell.2023.1123299. eCollection 2023. |
A heterozygous mutation in UBE2H in a patient with developmental delay leads to an aberrant brain development in zebrafish
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Citation:
Hum Genomics. 2023 May 19;17(1):44. doi: 10.1186/s40246-023-00491-7 Epub:
Not Epub Abstract:
Background: Ubiquitin-related rare diseases are generally characterized by developmental delays and mental retardation, but the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shin U, Choi Y, Ko HS, Myung K, Lee S, Cheon CK, Lee Y. A heterozygous mutation in UBE2H in a patient with developmental delay leads to an aberrant brain development in zebrafish. Hum Genomics. 2023 May 19;17(1):44. doi: 10.1186/s40246-023-00491-7. |
Embryonic Ethanol but Not Cannabinoid Exposure Affects Zebrafish Cardiac Development via Agrin and Sonic Hedgehog Interaction
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Citation:
Cells. 2023 May 6;12(9):1327. doi: 10.3390/cells12091327 Epub:
Not Epub Abstract:
Recent studies demonstrate the adverse effects of cannabinoids on development, including via pathways shared with ethanol... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang C, Ezem N, Mackinnon S, Cole GJ. Embryonic Ethanol but Not Cannabinoid Exposure Affects Zebrafish Cardiac Development via Agrin and Sonic Hedgehog Interaction. Cells. 2023 May 6;12(9):1327. doi: 10.3390/cells12091327. |
The challenge of dissecting gene function in model organisms: Tools to characterize genetic mutants and assess transcriptional adaptation in zebrafish
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Citation:
Methods Cell Biol. 2023;176:1-25. doi: 10.1016/bs.mcb.2022.12.019. Epub 2023 Jan 27 Epub:
Not Epub Abstract:
Genome editing technologies including the CRISPR/Cas9 system have greatly improved our knowledge of gene function and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cardenas-Rodriguez M, Drummond IA. The challenge of dissecting gene function in model organisms: Tools to characterize genetic mutants and assess transcriptional adaptation in zebrafish. Methods Cell Biol. 2023;176:1-25. doi: 10.1016/bs.mcb.2022.12.019. Epub 2023 Jan 27. |
Role of MicroRNAs and their Downstream Target Transcription Factors in Zebrafish Thrombopoiesis
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Citation:
Res Sq. 2023 Apr 24:rs.3.rs-2807790. doi: 10.21203/rs.3.rs-2807790/v1. Preprint Epub:
Not Epub Abstract:
Previous studies have shown that human platelets and megakaryocytes carry microRNAs suggesting their role in platelet function... Delivery Method:
Vivo-Morpholino piggyback Organism or Cell Type:
zebrafish Citation Extract: Qaryoute AA, Fallatah W, Dhinoja S, Raman R, Jagadeeswaran P. Role of MicroRNAs and their Downstream Target Transcription Factors in Zebrafish Thrombopoiesis. Res Sq. 2023 Apr 24:rs.3.rs-2807790. doi: 10.21203/rs.3.rs-2807790/v1. Preprint. |
Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor
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Citation:
Elife. 2023 May 10;12:e84036. doi: 10.7554/eLife.84036. Online ahead of print Epub:
Yes Abstract:
Natriuretic peptide signaling has been implicated in a broad range of physiological processes, regulating blood volume and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Devotta A, Juraver-Geslin H, Griffin C, Saint-Jeannet JP. Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor. Elife. 2023 May 10;12:e84036. doi: 10.7554/eLife.84036. Online ahead of print. |
Efficacy and Safety of Viltolarsen in Boys With Duchenne Muscular Dystrophy: Results From the Phase 2, Open-Label, 4-Year Extension Study
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Citation:
J Neuromuscul Dis. 2023;10(3):439-447. doi: 10.3233/JND-221656 Epub:
Not Epub Abstract:
Background: Duchenne muscular dystrophy (DMD) is caused by DMD gene mutations, resulting in absence of functional dystrophin... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Clemens PR, Rao VK, Connolly AM, Harper AD, Mah JK, McDonald CM, Smith EC, Zaidman CM, Nakagawa T; CINRG DNHS Investigators; Hoffman EP. Efficacy and Safety of Viltolarsen in Boys With Duchenne Muscular Dystrophy: Results From the Phase 2, Open-Label, 4-Year Extension Study. J Neuromuscul Dis. 2023;10(3):439-447. doi: 10.3233/JND-221656. |
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
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Citation:
Nat Struct Mol Biol. 2024 Aug;31(8):1198-1207. doi: 10.1038/s41594-024-01265-y. Epub 2024 Apr 2. PMID: 38565696; PMCID: PMC11329362 Epub:
Not Epub Abstract:
The conversion of phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 3,4,5-triphosphate by phosphoinositide 3-kinase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen CL, Syahirah R, Ravala SK, Yen YC, Klose T, Deng Q, Tesmer JJG. Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nat Struct Mol Biol. 2024 Aug;31(8):1198-1207. doi: 10.1038/s41594-024-01265-y. Epub 2024 Apr 2. PMID: 38565696; PMCID: PMC11329362. |