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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Normal Function of Myf5 During Gastrulation Is Required for Pharyngeal Arch Cartilage Development in Zebrafish Embryos

Authors:
Lin CY, Lee HC, Chen HC, Hsieh CC, Tsai HJ
Citation:
Zebrafish. 2013 Aug 31. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Abstract Myf5, a myogenic regulatory factor, plays a key role in regulating muscle differentiation. However, it is not known if...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, Lee HC, Chen HC, Hsieh CC, Tsai HJ. Normal Function of Myf5 During Gastrulation Is Required for Pharyngeal Arch Cartilage Development in Zebrafish Embryos. Zebrafish. 2013 Aug 31. [Epub ahead of print].

Opposing actions of histone deacetylase 1 and Notch signalling restrict expression of erm and fgf20a to hindbrain rhombomere centres during zebrafish neurogenesis

Authors:
Lightman EG, Harrison MRM, Cunliffe VT
Citation:
Int J Dev Biol. 2011;55:597-02
Epub:
Not Epub
Abstract:
The rate and pattern of neurogenesis in the developing vertebrate nervous system is controlled by a complex interplay of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lightman EG, Harrison MRM, Cunliffe VT. Opposing actions of histone deacetylase 1 and Notch signalling restrict expression of erm and fgf20a to hindbrain rhombomere centres during zebrafish neurogenesis. Int J Dev Biol. 2011;55:597-02.

Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus

Authors:
Lim CY, Reversade B, Knowles BB, Solter D
Citation:
Development. 2013 Feb;140(4):853-60. doi: 10.1242/dev.086611. Epub 2013 Jan 14
Epub:
Not Epub
Abstract:
Cellular differentiation during embryogenesis involves complex gene regulation to enable the activation and repression of genes...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lim CY, Reversade B, Knowles BB, Solter D. Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus. Development. 2013 Feb;140(4):853-60. doi: 10.1242/dev.086611. Epub 2013 Jan 14.

PAK1 regulates spindle microtubule organization during oocyte meiotic maturation

Authors:
Lin SL, Qi ST, Sun SC, Wang YP, Schatten H, Sun QY
Citation:
Front Biosci (Elite Ed). 2010 Jun 1;2:1254-64
Epub:
Not Epub
Abstract:
P21-activated kinase 1 (PAK1), an effector of Rho GTPase Rac 1 and Cdc42, is required for mitotic progression. However, its...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Lin SL, Qi ST, Sun SC, Wang YP, Schatten H, Sun QY. PAK1 regulates spindle microtubule organization during oocyte meiotic maturation. Front Biosci (Elite Ed). 2010 Jun 1;2:1254-64.

Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling

Authors:
Liu JAJ, Wu M-H, Yan CH, Chau BKH, So H, Ng A, Chan A, Cheah KSE, Briscoe J, Cheung M
Citation:
PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1211747110
Epub:
Not Epub
Abstract:
Coordination of neural crest cell (NCC) induction and delamination is orchestrated by several transcription factors. Among...
Delivery Method:
Injection then electroporation in vivo
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Liu JAJ, Wu M-H, Yan CH, Chau BKH, So H, Ng A, Chan A, Cheah KSE, Briscoe J, Cheung M. Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling. PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1211747110 .

Prdm14 acts upstream of islet2 transcription to regulate axon growth of primary motoneurons in zebrafish

Authors:
Liu C, Ma W, Su W, Zhang J
Citation:
Development. 2012 Dec;139(24):4591-600. doi: 10.1242/dev.083055. Epub 2012 Nov 7.
Epub:
Not Epub
Abstract:
The precise formation of three-dimensional motor circuits is essential for movement control. Within these circuits, motoneurons...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu C, Ma W, Su W, Zhang J. Prdm14 acts upstream of islet2 transcription to regulate axon growth of primary motoneurons in zebrafish. Development. 2012 Dec;139(24):4591-600. doi: 10.1242/dev.083055. Epub 2012 Nov 7..

Predicting the biodistribution of radiolabeled cMORF effector in MORF-pretargeted mice

Authors:
Liu G, Dou S, He J, Liu X, Rusckowski M, Hnatowich DJ
Citation:
Eur J Nucl Med Mol Imaging. 2007 Feb;34(2):237-46
Epub:
Not Epub
Abstract:
PURPOSE: Pretargeting with phosphorodiamidate morpholino oligomers (MORFs) involves administration of a MORF-conjugated anti-...
Delivery Method:
Injection
Organism or Cell Type:
mice, LS174T
Citation Extract:
Liu G, Dou S, He J, Liu X, Rusckowski M, Hnatowich DJ. Predicting the biodistribution of radiolabeled cMORF effector in MORF-pretargeted mice. Eur J Nucl Med Mol Imaging. 2007 Feb;34(2):237-46.

Preparation of (111)In-DTPA morpholino oligomer for low abdominal accumulation

Authors:
Liu G, Dou S, Rusckowski M, Greiner D, Hnatowich D
Citation:
Appl Radiat Isot. 2010 Sep;68(9):1709-14. doi: 10.1016/j.apradiso.2010.03.002
Epub:
Not Epub
Abstract:
An ability to quantitate the beta cell mass by noninvasive nuclear imaging will be very useful in the prevention, diagnosis,...
Link:
http://www.sciencedirect.com/science/article/pii/S096980431000120X
Citation Extract:
Liu G, Dou S, Rusckowski M, Greiner D, Hnatowich D. Preparation of (111)In-DTPA morpholino oligomer for low abdominal accumulation. Appl Radiat Isot. 2010 Sep;68(9):1709-14. doi: 10.1016/j.apradiso.2010.03.002.

Pretargeting in tumored mice with radiolabeled morpholino oligomer showing low kidney uptake

Authors:
Liu G, He J, Dou S, Gupta S, Vanderheyden JL, Rusckowski M, Hnatowich DJ
Citation:
Eur J Nucl Med Mol Imaging. 2004 Mar;31(3):417-24. Epub 2003 Dec 23
Epub:
Not Epub
Abstract:
We have recently shown that accumulation in mouse kidneys of technetium-99m labeled phosphorodiamidate morpholinos (MORFs)...
Delivery Method:
in vivo: injection
Organism or Cell Type:
nude mice
Citation Extract:
Liu G, He J, Dou S, Gupta S, Vanderheyden JL, Rusckowski M, Hnatowich DJ. Pretargeting in tumored mice with radiolabeled morpholino oligomer showing low kidney uptake. Eur J Nucl Med Mol Imaging. 2004 Mar;31(3):417-24. Epub 2003 Dec 23.

Pretargeting vs direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody

Authors:
Liu G, Dou S, Akalin A, Rusckowski M, Streeter PR, Shultz LD, Greiner DL
Citation:
Nucl Med Biol. 2012 Jul;39(5):645-51. doi: 10.1016/j.nucmedbio.2011.12.001. Epub 2012 Feb 10
Epub:
Not Epub
Abstract:
Introduction Our previous investigation showed the proof-of-concept of islet cell and islet imaging by pretargeting, however,...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, Dou S, Akalin A, Rusckowski M, Streeter PR, Shultz LD, Greiner DL. Pretargeting vs direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody. Nucl Med Biol. 2012 Jul;39(5):645-51. doi: 10.1016/j.nucmedbio.2011.12.001. Epub 2012 Feb 10.

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