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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.18.464758 Epub:
Not Epub Abstract:
In the vertebrate retina, an interplay between retinal ganglion cells (RGCs), amacrine and bipolar cells establishes a synaptic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ahmed M, Kojima Y, Masai I. Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.18.464758. |
Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways
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Citation:
Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3 Epub:
Not Epub Abstract:
The transcriptional effector SMAD4 is a core component of the TGF-β family signaling pathways. However, its role in vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS. Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways. Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3. |
NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration
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Citation:
Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5 Epub:
Not Epub Abstract:
Fish species, such as zebrafish (Danio rerio), can regenerate their appendages after amputation through the formation of a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F. NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5. |
Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway
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Citation:
Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print Epub:
Not Epub Abstract:
In the context of obesity-induced adipose tissue inflammation, migration of macrophages and their polarization from... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Chattopadhyay D, Das S, Guria S, Basu S, Mukherjee S. Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway. Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print. |
Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability
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Citation:
J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039. Epub:
Not Epub Abstract:
Background: Allergy regroups numerous complex and various diseases classified as IgE-dependent or non-dependent... Delivery Method:
Vivo-Morpholino, peptide-linked Organism or Cell Type:
cell culture: B cells, myeloma cells; InEps mice Citation Extract: Marchalot A, Horiot C, Lambert J-M, Carrion C, Oblet C, Pollet J, Cogné M, Moreau J, Laffleur B, Delpy L. Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability. J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039.. |
Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish
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Citation:
Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883 Epub:
Not Epub Abstract:
The failure of amyloid beta (Aβ) clearance is a major cause of Alzheimer’s disease, and the brain lymphatic systems play a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jeong Y-M, Lee J-G, Cho H-J, Lee WS, Jeong J, Lee J-S. Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish. Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883. |
Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis
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Citation:
Front Cell Dev Biol. 2021 Oct 13;9:709923. doi: 10.3389/fcell.2021.709923 Epub:
Not Epub Abstract:
Vertebrate erythropoiesis involves nuclear and chromatin condensation at the early stages of terminal differentiation, which is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu S, Chen K, Xu T, Ma K, Gao L, Fu C, Zhang W, Jing C, Ren C, Deng M, Chen Y, Zhou Y, Pan W, Jia X. Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis. Front Cell Dev Biol. 2021 Oct 13;9:709923. doi: 10.3389/fcell.2021.709923. |
Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish
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Citation:
PLoS Genet. 2021;17(11):e1009890. doi:10.1371/journal.pgen.1009890 Epub:
Not Epub Abstract:
In contrast to mammals, the zebrafish maintains its cardiomyocyte proliferation capacity throughout adulthood. However, neither... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bühler A, Gahr BM, Park D-D, Bertozzi A, Boos A, Dalvoy M, Pott A, Oswald F, Kovall RA, Kühn B, Weidinger G, Rottbauer W, Just S. Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish. PLoS Genet. 2021;17(11):e1009890. doi:10.1371/journal.pgen.1009890. |
Nuclear S-nitrosylation impacts tissue regeneration in zebrafish
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Citation:
Nat Comm. 2021;12(1):6282. doi:10.1038/s41467-021-26621-0 Epub:
Not Epub Abstract:
Despite the importance of nitric oxide signaling in multiple biological processes, its role in tissue regeneration remains... Delivery Method:
microinjection, Vivo-Morpholino retro-orbital injection Organism or Cell Type:
zebrafish Citation Extract: Matrone G, Jung SY, Choi JM, Jain A, Leung H-CE, Rajapakshe K, Coarfa C, Rodor J, Denvir MA, Baker AH, Cooke JP. Nuclear S-nitrosylation impacts tissue regeneration in zebrafish. Nat Comm. 2021;12(1):6282. doi:10.1038/s41467-021-26621-0. |
Zebrafish Paralogs brd2a and brd2b Are Needed for Proper Circulatory, Excretory and Central Nervous System Formation and Act as Genetic Antagonists during Development
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Citation:
J Dev Biol. 2021;9(4):46. doi:10.3390/jdb9040046 Epub:
Not Epub Abstract:
Brd2 belongs to the BET family of epigenetic transcriptional co-regulators that act as adaptor-scaffolds for the assembly of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Branigan GL, Olsen KS, Burda I, Haemmerle MW, Ho J, Venuto A, D’Antonio ND, Briggs IE, DiBenedetto AJ. Zebrafish Paralogs brd2a and brd2b Are Needed for Proper Circulatory, Excretory and Central Nervous System Formation and Act as Genetic Antagonists during Development. J Dev Biol. 2021;9(4):46. doi:10.3390/jdb9040046. |