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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation
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Citation:
Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w Epub:
Not Epub Abstract:
Neurofibromatosis Type 1 (NF1) is a genetic condition affecting approximately 1:3500 persons worldwide. The NF1 gene codes for... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: PC12 Citation Extract: Biayna J, Mazuelas H, Gel B, Terribas E, Dumbovic G, Rosas I, Fernández-Rodriguez J, Blanco I, Castellanos E, Carrió M, Lazaro C, Serra E. Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation. Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w. |
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides
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Citation:
Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disease caused by frameshift or nonsense mutations in the DMD gene... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture:CXMDJ immortalized myoblasts Citation Extract: Tone Y, Mamchaoui K, Tsoumpra MK, Hashimoto Y, Terada R, Maruyama R, Gait MJ, Arzumanov AA, McClorey G, Imamura M, Takeda S, Yokota T, Wood MJA, Mouly V, Aoki Y. Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides. Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print. |
Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation
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Citation:
Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693 Epub:
Not Epub Abstract:
Integrated molecular signals regulate cell fate decisions in the embryonic aortic endothelium to drive hematopoietic stem cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Maglitto A, Mariani SA, de Pater E, Rodriguez-Seoane C, Vink CS, Piao X, Lukke M-L, Dzierzak E. Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation. Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693. |
Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428386 Epub:
Not Epub Abstract:
The atrioventricular canal (AVC) is an essential feature of the heart, which separates the atrium from the ventricle. During... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Abu NK, Migdał M, Quinn TA, Poon K-L, Łapinski M, Sulej A, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C. Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428386. |
Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.12.426405 Epub:
Not Epub Abstract:
Convergent extension is an evolutionarily conserved collective cell movement that elongates the body axis of all animals and is... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Weng S, Huebner RJ, Wallingford JB. Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.12.426405 . |
Eya1-dependent homeostasis of morphogenetic territories during collective cell migration
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428404 Epub:
Not Epub Abstract:
Tissue remodeling presents an enormous challenge to the stability of intercellular signaling domains. Here we investigate this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Miranda-Rodríguez JR, Borges A, Pinto-Teixeira F, Wibowo I, Pogoda H-M, Hammerschmidt M, Kawakami K, López-Schier H. Eya1-dependent homeostasis of morphogenetic territories during collective cell migration. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428404 . |
Slit2 is necessary for optic axon organization in the zebrafish ventral midline
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Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.09.25.314062 Epub:
Not Epub Abstract:
The functional connection of the retina with the brain implies the extension of retinal ganglion cells axons through a long and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Davison C, Zolessi FR. Slit2 is necessary for optic axon organization in the zebrafish ventral midline. bioRxiv 2020;[preprint] doi:10.1101/2020.09.25.314062 . |
Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611 Epub:
Not Epub Abstract:
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know... Delivery Method:
injection then electroporation Organism or Cell Type:
Coturnix japonica (quail) embryo Citation Extract: Romanos M, Allio G, Combres L, Médevielle F, Escalas N, Soula C, Steventon B, Trescases A, Bénazéraf. Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611 . |
Tacc3 modulates microtubule network dynamicity and focal adhesion remodeling to affect cranial neural crest cell migration in Xenopus laevis
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430297 Epub:
Not Epub Abstract:
Coordinated cell migration is critical during embryogenesis, as cells must leave their point of origin, navigate a complex... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Bearce EA, Pratt B, Rutherford EL, Carandang LA, Lowery L. Tacc3 modulates microtubule network dynamicity and focal adhesion remodeling to affect cranial neural crest cell migration in Xenopus laevis. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430297 . |
Bidirectional neuronal migration coordinates retinal morphogenesis by preventing spatial competition
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430189 Epub:
Not Epub Abstract:
While the design of industrial products is often optimized for the sequential assembly of single components, organismal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rocha-Martins M, Kretzschmar J, Nerli E, Weigert M, Icha J, Myers EW, Norden C. Bidirectional neuronal migration coordinates retinal morphogenesis by preventing spatial competition. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430189. |