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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation

Authors:
Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H
Citation:
iScience. 2019;[Epub ahead of print] doi:10.1016/j.isci.2019.04.007
Epub:
Yes
Abstract:
Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with Cereblon (...
Link:
https://www.sciencedirect.com/science/article/pii/S258900421930104X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H . Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation. iScience. 2019;[Epub ahead of print] doi:10.1016/j.isci.2019.04.007.

A High-Throughput Assay for Congenital and Age-Related Eye Diseases in Zebrafish

Authors:
Brastrom LK, Scott CA, Dawson DV, Slusarski DC
Citation:
Biomedicines. 2019;7(2):28 doi:10.3390/biomedicines7020028
Epub:
Not Epub
Abstract:
Debilitating visual impairment caused by cataracts or microphthalmia is estimated to affect roughly 20 million people in the...
Link:
https://www.mdpi.com/2227-9059/7/2/28/htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brastrom LK, Scott CA, Dawson DV, Slusarski DC. A High-Throughput Assay for Congenital and Age-Related Eye Diseases in Zebrafish. Biomedicines. 2019;7(2):28 doi:10.3390/biomedicines7020028.

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer

Authors:
Daulat AM, Finetti P, Revinski D, Wagner MS, Camoin L, Audebert S, Birnbaum D, Kodjabachian L, Borg J-P, Bertucci F
Citation:
Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z
Epub:
Yes
Abstract:
Background: Triple-negative breast cancers (TNBC) are poor-prognosis tumours candidate to chemotherapy as only systemic...
Link:
https://www.nature.com/articles/s41416-019-0448-z
Organism or Cell Type:
Xenopus
Citation Extract:
Daulat AM, Finetti P, Revinski D, Wagner MS, Camoin L, Audebert S, Birnbaum D, Kodjabachian L, Borg J-P, Bertucci F. ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer. Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z.

Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation

Authors:
Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang C-C, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK
Citation:
JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460
Epub:
Yes
Abstract:
Biomechanical forces and endothelial-to-mesenchymal transition (EndoMT) are known to mediate valvulogenesis. However, the...
Link:
https://insight.jci.org/articles/view/124460
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang C-C, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460.

The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells

Authors:
Ratzan W, Rayaprolu V, Killian SE, Bradley R, Kohout SC
Citation:
PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056
Epub:
Not Epub
Abstract:
Voltage-sensing phosphatases (VSPs) are transmembrane proteins that couple changes in membrane potential to hydrolysis of...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209056
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ratzan W, Rayaprolu V, Killian SE, Bradley R, Kohout SC. The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells. PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056.

Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis

Authors:
Gong B, Li Z, Xiao W, Li G, Ding S, Meng A, Jia S
Citation:
Nat Comm. 2019;10(1):1606 doi:10.1038/s41467-019-09604-0
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor (VEGF) regulates vasculogenesis by using its tyrosine kinase receptors. However, little is...
Link:
https://www.nature.com/articles/s41467-019-09604-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong B, Li Z, Xiao W, Li G, Ding S, Meng A, Jia S. Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis. Nat Comm. 2019;10(1):1606 doi:10.1038/s41467-019-09604-0.

Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish

Authors:
Pociute K, Schumacher JA, Sumanas S
Citation:
BMC Dev Biol. 2019 Apr 5;19(1):6. doi: 10.1186/s12861-019-0188-6
Epub:
Not Epub
Abstract:
BACKGROUND: C-lectin family 14 Member A (Clec14a) is a transmembrane protein specifically expressed in vascular endothelial...
Link:
https://bmcdevbiol.biomedcentral.com/articles/10.1186/s12861-019-0188-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pociute K, Schumacher JA, Sumanas S. Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish. BMC Dev Biol. 2019 Apr 5;19(1):6. doi: 10.1186/s12861-019-0188-6.

Analysis of microRNA functions

Authors:
Remsburg C, Konrad K, Sampilo NF, Song JL
Citation:
Methods Cell Biol. 2019;151:323-334. doi: 10.1016/bs.mcb.2018.10.005. Epub 2018 Dec 11
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are small non-coding RNAs that repress the translation and reduce the stability of target mRNAs in animal...
Link:
https://www.sciencedirect.com/science/article/pii/S0091679X18301432
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Remsburg C, Konrad K, Sampilo NF, Song JL. Analysis of microRNA functions. Methods Cell Biol. 2019;151:323-334. doi: 10.1016/bs.mcb.2018.10.005. Epub 2018 Dec 11.

Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?

Authors:
Zimmer AM, Pan YK, Chandrapalan T, Kwong RWM, Perry SF
Citation:
J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review
Epub:
Not Epub
Abstract:
Loss-of-function technologies, such as morpholino- and RNAi-mediated gene knockdown, and TALEN- and CRISPR/Cas9-mediated gene...
Link:
http://jeb.biologists.org/content/222/7/jeb175737
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zimmer AM, Pan YK, Chandrapalan T, Kwong RWM, Perry SF. Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?. J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review.

Prostaglandin signaling regulates renal multiciliated cell specification and maturation

Authors:
Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA
Citation:
Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116
Epub:
Yes
Abstract:
Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direct fluid flow. MCC...
Link:
https://www.pnas.org/content/early/2019/04/03/1813492116
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA. Prostaglandin signaling regulates renal multiciliated cell specification and maturation. Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116.

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