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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
A U2-snRNP-independent role of SF3b in promoting mRNA export
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Citation:
Proc Natl Acad Sci USA. 2019;116(16):7837-46. doi:10.1073/pnas.1818835116 Epub:
Not Epub Abstract:
To ensure efficient and accurate gene expression, pre-mRNA processing and mRNA export need to be balanced. However, how this... Delivery Method:
microinjection Organism or Cell Type:
cell culture Citation Extract: Wang K, Yin C, Du X, Chen S, Wang J, Zhang L, Wang L, Yu Y, Chi B, Shi M, Wang C, Reed R, Zhou Y, Huang J, Cheng H. A U2-snRNP-independent role of SF3b in promoting mRNA export. Proc Natl Acad Sci USA. 2019;116(16):7837-46. doi:10.1073/pnas.1818835116 . |
Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis
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Citation:
Int J Dev Biol. 2019;63(1-2):29-35. doi: 10.1387/ijdb.180184kt Epub:
Not Epub Abstract:
Latrophilin2 (Lphn2) is an adhesion-class of G protein-coupled receptor with an unknown function in development. Here, we show... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Yokote N, Suzuki-Kosaka MY, Michiue T, Hara T, Tanegashima K. Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis. Int J Dev Biol. 2019;63(1-2):29-35. doi: 10.1387/ijdb.180184kt. |
Loss of PKC mu function induces cytoskeletal defects in mouse oocyte meiosis
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Citation:
J Cell Physiol. 2019 Mar 25. doi: 10.1002/jcp.28487. [Epub ahead of print] Epub:
Yes Abstract:
Cytoskeleton which includes microtubule and actin filaments plays important roles during mammalian oocyte maturation. In the... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhang Y, Wu LL, Wan X, Wang HH, Li XH, Pan ZN, Sun SC. Loss of PKC mu function induces cytoskeletal defects in mouse oocyte meiosis. J Cell Physiol. 2019 Mar 25. doi: 10.1002/jcp.28487. [Epub ahead of print]. |
Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition
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Citation:
Development. 2019;[Epub ahead of print] doi:10.1242/dev.171017 Epub:
Yes Abstract:
miR-203 is a tumor-suppressor microRNA with known functions in cancer metastasis. Here, we explore its normal developmental... Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Sánchez-Vásquez E, Bronner ME, Strobl-Mazzulla PH. Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition. Development. 2019;[Epub ahead of print] doi:10.1242/dev.171017. |
A threonyl-tRNA synthetase-mediated translation initiation machinery
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Citation:
Nat Comm. 2019;10:1357. doi:10.1038/s41467-019-09086-0 Epub:
Not Epub Abstract:
A fundamental question in biology is how vertebrates evolved and differ from invertebrates, and little is known about... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jeong SJ, Park S, Nguyen LT, Hwang J, Lee E-Y, Giong H-K, Lee J-S, Yoon I, Lee J-H, Kim JH, Kim HK, Kim D, Yang WS, Kim S-Y, Lee CY, Yu K, Sonenberg N, Kim MH, Kim S. A threonyl-tRNA synthetase-mediated translation initiation machinery. Nat Comm. 2019;10:1357. doi:10.1038/s41467-019-09086-0. |
A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies
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Citation:
JCI Insight. 2019 Mar 21;4(6). pii: 124403. doi: 10.1172/jci.insight.124403. eCollection 2019 Mar 21 Epub:
Not Epub Abstract:
The clinical application of advanced next-generation sequencing technologies is increasingly uncovering novel classes of... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human dermal fibroblasts, HEK293T Citation Extract: Bolduc V, Foley AR, Solomon-Degefa H, Sarathy A, Donkervoort S, Hu Y, Chen GS, Sizov K, Nalls M, Zhou H, Aguti S, Cummings BB, Lek M, Tukiainen T, Marshall JL, Regev O, Marek-Yagel D, Sarkozy A, Butterfield RJ, Jou C, Jimenez-Mallebrera C, Li Y, Gartioux C, Mamchaoui K, Allamand V, Gualandi F, Ferlini A, Hanssen E; COL6A1 Intron 11 Study Group, Wilton SD, Lamandé SR, MacArthur DG, Wagener R, Muntoni F, Bönnemann CG. A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies. JCI Insight. 2019 Mar 21;4(6). pii: 124403. doi: 10.1172/jci.insight.124403. eCollection 2019 Mar 21. |
Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish
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Citation:
Sci Rep. 2019 Mar 18;9(1):4750. doi: 10.1038/s41598-019-41202-4 Epub:
Not Epub Abstract:
Although structural nuclear pore proteins (nucleoporins) are seemingly required in every cell type to assemble a functional... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cianciolo Cosentino C, Berto A, Pelletier S, Hari M, Loffing J, Neuhauss SCF, Doye V. Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish. Sci Rep. 2019 Mar 18;9(1):4750. doi: 10.1038/s41598-019-41202-4. |
Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway
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Citation:
J Cell Sci. 2019 Mar 19. pii: jcs.230201. doi: 10.1242/jcs.230201. [Epub ahead of print] Epub:
Yes Abstract:
Alternative splicing (AS) strongly increases proteome diversity and functionality in eukaryotic cells. Protein secretion is a... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture:HEK293T Citation Extract: Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F. Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway. J Cell Sci. 2019 Mar 19. pii: jcs.230201. doi: 10.1242/jcs.230201. [Epub ahead of print]. |
Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/583179 Epub:
Not Epub Abstract:
Whether cell forces or extracellular matrix (ECM) can impact genome integrity is largely unclear. Here, acute perturbations (~... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
organ culture: Gallus gallus (chick) hearts Citation Extract: Cho S, Vashisth M, Abbas A, Majkutv S, Vogel K, Xia Y, Ivanovska IL, Irianto J, Tewari M, Zhu K, Tichy ED, Mourkioti F, Tang H-Y, Greenberg R, Prosser BL, Discher DE. Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest. bioRxiv. 2019;[preprint] doi:10.1101/583179. |
Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border
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Citation:
PLoS ONE. 2019;14(3):e0214063. https://doi.org/10.1371/journal.pone.0214063 Epub:
Not Epub Abstract:
Neural tube defects (NTDs), one of the most common birth defects in human, present a multifactorial etiology with a poorly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Narboux-Neme N, Ekker M, Levi G, Heude E. Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border. PLoS ONE. 2019;14(3):e0214063. https://doi.org/10.1371/journal.pone.0214063. |