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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Wolf-Hirschhorn Syndrome-associated genes are enriched in motile neural crest and affect craniofacial development in Xenopus laevis

Authors:
Mills A, Bearce E, Cella R, Kim SW, Selig M, Lee S, Lowery LA
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/471672
Epub:
Yes
Abstract:
Wolf-Hirschhorn Syndrome (WHS) is a human developmental disorder arising from a hemizygous perturbation, typically a...
Link:
https://www.biorxiv.org/content/early/2018/11/15/471672.1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mills A, Bearce E, Cella R, Kim SW, Selig M, Lee S, Lowery LA. Wolf-Hirschhorn Syndrome-associated genes are enriched in motile neural crest and affect craniofacial development in Xenopus laevis. bioRxive. 2018;[Preprint] doi:10.1101/471672.

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish

Authors:
Reuter I, Jaeckels J, Kneitz S, Kuper J, Lesch K-P, Lillesaar C
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/477323
Epub:
Yes
Abstract:
In most vertebrates, including zebrafish, the hypothalamic serotonergic cerebrospinal fluid-contacting (CSF-c) cells constitute...
Link:
https://www.biorxiv.org/content/early/2018/11/24/477323
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reuter I, Jaeckels J, Kneitz S, Kuper J, Lesch K-P, Lillesaar C. Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish. bioRxive. 2018;[Preprint] doi:10.1101/477323 .

Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects

Authors:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL
Citation:
Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are highly conserved, small non-coding RNAs that regulate gene expressions by binding to the 3'...
Link:
http://dev.biologists.org/content/145/23/dev167130
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL. Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects. Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print].

Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43

Authors:
Bhattacharya S, Gargiulo D, Iovine MK
Citation:
Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975
Epub:
Yes
Abstract:
The correct positioning of joints in the vertebrate skeleton is not well understood. Mutations in connexin43 (cx43) cause the...
Link:
http://dev.biologists.org/content/145/23/dev166975
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhattacharya S, Gargiulo D, Iovine MK. Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43. Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975.

The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis

Authors:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W
Citation:
Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background and aims: It has been well established that ezetimibe blocks cholesterol absorption to prevent the negative effects...
Link:
https://www.sciencedirect.com/science/article/pii/S0021915018314710
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W. The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print].

CDK12 regulates DNA repair genes by suppressing intronic polyadenylation

Authors:
Dubbury SJ, Boutz PL, Sharp PA
Citation:
Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y
Epub:
Yes
Abstract:
Mutations that attenuate homologous recombination (HR)-mediated repair promote tumorigenesis and sensitize cells to...
Link:
https://www.nature.com/articles/s41586-018-0758-y
Organism or Cell Type:
cell culture: mouse ES cells
Citation Extract:
Dubbury SJ, Boutz PL, Sharp PA. CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y.

Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene

Authors:
Linhartová Z, Saito T, Kašpar V, Rodina M, Prášková E, Hagihara S, Pšenička M
Citation:
Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11
Epub:
Not Epub
Abstract:
Sturgeons (chondrostean, acipenseridae) are ancient fish species, widely known for their caviar. Nowadays, most of them are...
Link:
https://www.sciencedirect.com/science/article/pii/S0093691X15003453
Delivery Method:
microinjection
Organism or Cell Type:
Acipenser ruthenus (sturgeon)
Citation Extract:
Linhartová Z, Saito T, Kašpar V, Rodina M, Prášková E, Hagihara S, Pšenička M. Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene. Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11.

Deletion of Pr72 causes cardiac developmental defects in Zebrafish

Authors:
Song G, Han M, Li Z, Gan X, Chen X, Yang J, Dong S, Yan M, Wan J, Wang Y, Huang Z, Yin Z, Zheng F
Citation:
PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883
Epub:
Not Epub
Abstract:
The alpha regulator subunit B'' of protein phosphatase 2 (PPP2R3A), a regulatory subunit of protein phosphatase 2A (...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206883
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Song G, Han M, Li Z, Gan X, Chen X, Yang J, Dong S, Yan M, Wan J, Wang Y, Huang Z, Yin Z, Zheng F. Deletion of Pr72 causes cardiac developmental defects in Zebrafish. PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883.

Functional role of pax6 in eye and central nervous system development in the annelid Capitella teleta

Authors:
Klann M, Seaver EC
Citation:
bioRxive. 2018;[preprint] doi:10.1101/481135
Epub:
Not Epub
Abstract:
The transcription factor Pax6 is an important regulator of early animal development. Loss of function mutations of pax6 in a...
Link:
https://www.biorxiv.org/content/early/2018/11/28/481135
Delivery Method:
microinjection
Organism or Cell Type:
Capitella teleta (annelid)
Citation Extract:
Klann M, Seaver EC. Functional role of pax6 in eye and central nervous system development in the annelid Capitella teleta. bioRxive. 2018;[preprint] doi:10.1101/481135.

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Authors:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T
Citation:
Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076
Epub:
Not Epub
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise in the embryonic dorsal aorta (DA) through a Runx1-dependent process of...
Link:
http://www.bloodjournal.org/content/132/Suppl_1/330
Organism or Cell Type:
zebrafish
Citation Extract:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T. Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo. Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076.

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