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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Wars2 is a determinant of angiogenesis

Authors:
Wang M, Sips P, Khin E, Rotival M, Sun X, Ahmed R, Widjaja AA, Schafer S, Yusoff P, Choksi PK, Ko NSJ, Singh MK, Epstein D, Guan Y, Houštěk J, Mracek T, Nuskova H, Mikell B, Tan J, Pesce F, Kolar F, Bottolo L, Mancini M, Hubner N, Pravenec M, Petretto E, MacRae C, Cook SA
Citation:
Nat Comm. 2016;7:12061. doi:10.1038/ncomms12061
Epub:
Not Epub
Abstract:
Coronary flow (CF) measured ex vivo is largely determined by capillary density that reflects angiogenic vessel formation in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang M, Sips P, Khin E, Rotival M, Sun X, Ahmed R, Widjaja AA, Schafer S, Yusoff P, Choksi PK, Ko NSJ, Singh MK, Epstein D, Guan Y, Houštěk J, Mracek T, Nuskova H, Mikell B, Tan J, Pesce F, Kolar F, Bottolo L, Mancini M, Hubner N, Pravenec M, Petretto E, MacRae C, Cook SA. Wars2 is a determinant of angiogenesis. Nat Comm. 2016;7:12061. doi:10.1038/ncomms12061.

Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation

Authors:
Sako K, Pradhan SJ, Barone V, Ingles-Prieto Á, Müller P, Ruprecht V, Čapek D, Galande S, Janovjak H, Heisenberg C-P
Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.036
Epub:
Yes
Abstract:
During metazoan development, the temporal pattern of morphogen signaling is critical for organizing cell fates in space and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sako K, Pradhan SJ, Barone V, Ingles-Prieto Á, Müller P, Ruprecht V, Čapek D, Galande S, Janovjak H, Heisenberg C-P. Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.036.

Dpp/BMP2-4 Mediates Signaling from the D-Quadrant Organizer in a Spiralian Embryo

Authors:
Lambert JD, Johnson AB, Hudson CN, Chan A
Citation:
Curr Biol. 2016;[Epub ahead of print] doi:10.1016/j.cub.2016.05.059
Epub:
Not Epub
Abstract:
In some animal groups, the secondary embryonic axis is patterned by a small group of cells, often called an organizer, that...
Delivery Method:
microinjection
Organism or Cell Type:
Ilyanassa (marine snail)
Citation Extract:
Lambert JD, Johnson AB, Hudson CN, Chan A. Dpp/BMP2-4 Mediates Signaling from the D-Quadrant Organizer in a Spiralian Embryo. Curr Biol. 2016;[Epub ahead of print] doi:10.1016/j.cub.2016.05.059.

Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro

Authors:
Sato Y, Sato S, Kikuchi T, Nonaka A, Kumagaia Y, Sasaki A, Kobayashi M
Citation:
Anal Biochem. 2016;209:41-5. doi:10.1016/j.ab.2016.06.032
Epub:
Yes
Abstract:
Knockdown of gene expression by antisense morpholino oligos (MOs) is a simple and effective method for analyzing the roles of...
Delivery Method:
Endo-Porter
Organism or Cell Type:
preimplantation mouse embryo
Citation Extract:
Sato Y, Sato S, Kikuchi T, Nonaka A, Kumagaia Y, Sasaki A, Kobayashi M. Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro. Anal Biochem. 2016;209:41-5. doi:10.1016/j.ab.2016.06.032.

Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis

Authors:
Liu H-H, Cline HT
Citation:
J Neurosci. 2016;36(27):7325-7339. doi:10.1523/JNEUROSCI.4282-15.2016
Epub:
Not Epub
Abstract:
Fragile X mental retardation protein (FMRP) is thought to regulate neuronal plasticity by limiting dendritic protein synthesis...
Organism or Cell Type:
Xenopus
Citation Extract:
Liu H-H, Cline HT. Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis. J Neurosci. 2016;36(27):7325-7339. doi:10.1523/JNEUROSCI.4282-15.2016.

Regulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explants

Authors:
Wallkamm V, Rahm K, Schmoll J, Kaufmann LT, Brinkmann E, Schunk J, Kraft B, Wedlich D, Gradl D
Citation:
BMC Biology. 2016;14:55. doi:10.1186/s12915-016-0278-x
Epub:
Not Epub
Abstract:
Background: A tight regulation of the Wnt-signaling network, activated by 19 Wnt molecules and numerous receptors and co-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Wallkamm V, Rahm K, Schmoll J, Kaufmann LT, Brinkmann E, Schunk J, Kraft B, Wedlich D, Gradl D. Regulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explants. BMC Biology. 2016;14:55. doi:10.1186/s12915-016-0278-x.

Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent

Authors:
Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, Le Moigne V, Vilchèze C, Guérardel Y, Lutfalla G, Herrmann J-L, Jacobs WR Jr, Kremer L
Citation:
PNAS. 2016;[Epub ahead of print] doi:10.1073/pnas.1605477113
Epub:
Yes
Abstract:
Mycobacterium abscessus (Mabs) is a rapidly growing Mycobacterium and an emerging pathogen in humans. Transitioning from a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, Le Moigne V, Vilchèze C, Guérardel Y, Lutfalla G, Herrmann J-L, Jacobs WR Jr, Kremer L. Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent. PNAS. 2016;[Epub ahead of print] doi:10.1073/pnas.1605477113 .

Increasing the Detection Sensitivity for DNA-Morpholino Hybridization in Sub-Nanomolar Regime by Enhancing the Surface Ion Conductance of PEDOT:PSS Membrane in a Microchannel

Authors:
Wei X, Panindre P, Zhang Q, Song Y-A
Citation:
ACS Sens. 2016;[Epub ahead ofprint] doi:10.1021/acssensors.6b00169
Epub:
Yes
Abstract:
Electrokinetic concentration based on ion concentration polarization (ICP) offers a unique possibility to increase detection...
Citation Extract:
Wei X, Panindre P, Zhang Q, Song Y-A. Increasing the Detection Sensitivity for DNA-Morpholino Hybridization in Sub-Nanomolar Regime by Enhancing the Surface Ion Conductance of PEDOT:PSS Membrane in a Microchannel. ACS Sens. 2016;[Epub ahead ofprint] doi:10.1021/acssensors.6b00169.

Antisense pre-treatment increases gene therapy efficacy in dystrophic muscles

Authors:
Peccate C, Mollard A, Le Hir M, Julien L, McClorey G, Jarmin S, Le Heron A, Dickson G, Benkhelifa-Ziyyat S, Piétri-Rouxel F, Wood MJ, Voit T, Lorain S
Citation:
Hum Mol Genet. 2016 Jul 4. pii: ddw201. [Epub ahead of print]
Epub:
Yes
Abstract:
In preclinical models for Duchenne muscular dystrophy, dystrophin restoration during AAV-U7-mediated exon-skipping therapy was...
Delivery Method:
injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Peccate C, Mollard A, Le Hir M, Julien L, McClorey G, Jarmin S, Le Heron A, Dickson G, Benkhelifa-Ziyyat S, Piétri-Rouxel F, Wood MJ, Voit T, Lorain S. Antisense pre-treatment increases gene therapy efficacy in dystrophic muscles. Hum Mol Genet. 2016 Jul 4. pii: ddw201. [Epub ahead of print].

Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis

Authors:
Fujii T, Tsunesumi SI, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, Watanabe S
Citation:
Sci Rep. 2016 Jul 5;6:29157. doi: 10.1038/srep29157
Epub:
Not Epub
Abstract:
Methylation of histone tails plays a pivotal role in the regulation of a wide range of biological processes. SET and MYND...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fujii T, Tsunesumi SI, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, Watanabe S. Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis. Sci Rep. 2016 Jul 5;6:29157. doi: 10.1038/srep29157.

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