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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

IFT46 plays crucial roles in craniofacial and cilia development

Authors:
Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS
Citation:
Biochem Biophys Res Commun. 2016 Jun 16. pii: S0006-291X(16)31001-4. doi: 10.1016/j.bbrc.2016.06.083. [Epub ahead of print]
Epub:
Yes
Abstract:
The intraflagellar transport (IFT) system is essential for bidirectional movement of ciliary components from the basal body to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS. IFT46 plays crucial roles in craniofacial and cilia development. Biochem Biophys Res Commun. 2016 Jun 16. pii: S0006-291X(16)31001-4. doi: 10.1016/j.bbrc.2016.06.083. [Epub ahead of print].

Beneficial roles of melanoma cell adhesion molecule in spinal cord transection recovery in adult zebrafish

Authors:
Liu CJ, Xie L, Cui C, Chu M, De Zhao H, Yao L, Li YH, Schachner M, Shen YQ
Citation:
J Neurochem. 2016 Jun 18. doi: 10.1111/jnc.13707. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Melanoma cell adhesion molecule (MCAM) is a multifunctional protein involved in miscellaneous processes, including development...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu CJ, Xie L, Cui C, Chu M, De Zhao H, Yao L, Li YH, Schachner M, Shen YQ. Beneficial roles of melanoma cell adhesion molecule in spinal cord transection recovery in adult zebrafish. J Neurochem. 2016 Jun 18. doi: 10.1111/jnc.13707. [Epub ahead of print].

Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity

Authors:
Eichner R, Heider M, Fernández-Sáiz V, van Bebber F, Garz AK, Lemeer S, Rudelius M, Targosz BS, Jacobs L, Knorn AM, Slawska J, Platzbecker U, Germing U, Langer C, Knop S, Einsele H, Peschel C, Haass C, Keller U, Schmid B, Götze KS, Kuster B, Bassermann F
Citation:
Nat Med. 2016 Jun 13. doi: 10.1038/nm.4128. [Epub ahead of print]
Epub:
Yes
Abstract:
Immunomodulatory drugs (IMiDs), such as thalidomide and its derivatives lenalidomide and pomalidomide, are key treatment...
Organism or Cell Type:
zebrafish
Citation Extract:
Eichner R, Heider M, Fernández-Sáiz V, van Bebber F, Garz AK, Lemeer S, Rudelius M, Targosz BS, Jacobs L, Knorn AM, Slawska J, Platzbecker U, Germing U, Langer C, Knop S, Einsele H, Peschel C, Haass C, Keller U, Schmid B, Götze KS, Kuster B, Bassermann F. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016 Jun 13. doi: 10.1038/nm.4128. [Epub ahead of print].

Epigenetic activation of Sox2 gene in the developing vertebrate neural plate

Authors:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH
Citation:
Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20
Epub:
Not Epub
Abstract:
One of the earliest manifestations of neural induction is onset of expression of the neural marker Sox2, mediated by the...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH. Epigenetic activation of Sox2 gene in the developing vertebrate neural plate. Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20.

Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells

Authors:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T
Citation:
Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595
Epub:
Yes
Abstract:
Purpose: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive human T-cell malignancy induced by human T-lymphotrophic virus-...
Organism or Cell Type:
cell culture: adult T-cell leukemia/lymphoma cells
Citation Extract:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T. Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells. Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595.

A novel function of calcitonin gene-related peptide in body fluid Cl− homeostasis

Authors:
Wang Y-F, Lafont A-G, Lee Y-C, Hwang P-P
Citation:
Proc Royal Soc B Biol. 2016;[Epub ahead of print] doi:10.1098/rspb.2016.0684
Epub:
Yes
Abstract:
Vertebrates need to maintain extracellular chloride (Cl−) concentrations to ensure the normal operation of physiological...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y-F, Lafont A-G, Lee Y-C, Hwang P-P. A novel function of calcitonin gene-related peptide in body fluid Cl− homeostasis. Proc Royal Soc B Biol. 2016;[Epub ahead of print] doi:10.1098/rspb.2016.0684.

Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos

Authors:
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM
Citation:
Environ Health Perspect. 2016 Nov;124(11):1766-1775. doi:10.1289/EHP141
Epub:
Yes
Abstract:
Exposure to the commonly used dithiocarbamate (DTC) pesticide ziram is associated with an increased risk of developing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM. Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos. Environ Health Perspect. 2016 Nov;124(11):1766-1775. doi:10.1289/EHP141.

Dolichol-phosphate mannose synthase depletion in zebrafish leads to dystrophic muscle with hypoglycosylated α-dystroglycan

Authors:
Marchese M, Pappalardo A, Baldacci J, Verri T, Doccini S, Cassandrini D, Bruno C, Fiorillo C, Garcia-Gil M, Bertini E, Pitto L, Santorelli FM
Citation:
Biochem Biophys Res Commun. 2016 Jun 9. pii: S0006-291X(16)30951-2. doi: 10.1016/j.bbrc.2016.06.033. [Epub ahead of print]
Epub:
Yes
Abstract:
Defective dolichol-phosphate mannose synthase (DPMS) complex is a rare cause of congenital muscular dystrophy associated with...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marchese M, Pappalardo A, Baldacci J, Verri T, Doccini S, Cassandrini D, Bruno C, Fiorillo C, Garcia-Gil M, Bertini E, Pitto L, Santorelli FM. Dolichol-phosphate mannose synthase depletion in zebrafish leads to dystrophic muscle with hypoglycosylated α-dystroglycan. Biochem Biophys Res Commun. 2016 Jun 9. pii: S0006-291X(16)30951-2. doi: 10.1016/j.bbrc.2016.06.033. [Epub ahead of print].

Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation

Authors:
Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J, Jho EH
Citation:
Cell Death Differ. 2016 Jun 10. doi: 10.1038/cdd.2016.54. [Epub ahead of print]
Epub:
Yes
Abstract:
Merlin, encoded by the NF2 gene, is a tumor suppressor that acts by inhibiting mitogenic signaling and is mutated in...
Citation Extract:
Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J, Jho EH. Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation. Cell Death Differ. 2016 Jun 10. doi: 10.1038/cdd.2016.54. [Epub ahead of print].

Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer

Authors:
Zhang JF, Jiang Z, Liu X, Meng A
Citation:
Development. 2016 Jun 10. pii: dev.132969. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The kupffer's vesicle (KV) is the so-called left-right organizer in teleost fishes. KV is formed from dorsal forerunner...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang JF, Jiang Z, Liu X, Meng A. Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016 Jun 10. pii: dev.132969. [Epub ahead of print].

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