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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Guide for Morpholino Users: Toward Therapeutics

Authors:
Moulton JD
Citation:
J Drug Discov Develop and Deliv. 2016;3(2):1023
Epub:
Not Epub
Abstract:
Morpholino oligos are uncharged molecules for blocking sites on RNA. They are specific, soluble, non-toxic, stable, and...
Citation Extract:
Moulton JD. Guide for Morpholino Users: Toward Therapeutics. J Drug Discov Develop and Deliv. 2016;3(2):1023.

SUMOylation regulates growth factor independence 1 in transcriptional control and hematopoiesis

Authors:
Andrade D, Velinder M, Singer J, Maese L, Bareyan D, Nguyen H, Chandrasekharan MB, Lucente H, McClellan D, Jones D, Sharma S, Liu F, Engel ME
Citation:
Mol Cell Biol. 2016;36:1438–1450. doi:10.1128/MCB.01001-15
Epub:
Not Epub
Abstract:
Cell fate specification requires precise coordination of transcription factors and their regulators to achieve fidelity and...
Organism or Cell Type:
zebrafish
Citation Extract:
Andrade D, Velinder M, Singer J, Maese L, Bareyan D, Nguyen H, Chandrasekharan MB, Lucente H, McClellan D, Jones D, Sharma S, Liu F, Engel ME. SUMOylation regulates growth factor independence 1 in transcriptional control and hematopoiesis. Mol Cell Biol. 2016;36:1438–1450. doi:10.1128/MCB.01001-15.

Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes

Authors:
Hostelley TL, Sukanya Lodh S, Zaghloul NA
Citation:
BMC Genomics. 2016;17:318. doi:10.1186/s12864-016-2679-1
Epub:
Not Epub
Abstract:
Background: Bardet-Biedl Syndrome (BBS) and Alström Syndrome are two pleiotropic ciliopathies with significant phenotypic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hostelley TL, Sukanya Lodh S, Zaghloul NA. Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes. BMC Genomics. 2016;17:318. doi:10.1186/s12864-016-2679-1.

Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21)

Authors:
Heon E, Kim G, Qin S, Garrison JE, Tavares E, Vincent A, Nuangchamnong N, Scott CA, Slusarski DC, Sheffield VC
Citation:
Hum Mol Genet. 2016 Mar 22. pii: ddw096. [Epub ahead of print]
Epub:
Yes
Abstract:
Bardet Biedl syndrome (BBS) is a multisystem genetically heterogeneous ciliopathy that most commonly leads to obesity,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heon E, Kim G, Qin S, Garrison JE, Tavares E, Vincent A, Nuangchamnong N, Scott CA, Slusarski DC, Sheffield VC. Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21). Hum Mol Genet. 2016 Mar 22. pii: ddw096. [Epub ahead of print].

An anterior signaling center patterns and sizes the anterior neuroectoderm of the sea urchin embryo

Authors:
Range RC, Wei Z
Citation:
Development. 2016 Mar 7. pii: dev.128165. [Epub ahead of print]
Epub:
Yes
Abstract:
Anterior signaling centers are essential to specify and pattern the early anterior neuroectoderm (ANE) of many deuterostome...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Range RC, Wei Z. An anterior signaling center patterns and sizes the anterior neuroectoderm of the sea urchin embryo. Development. 2016 Mar 7. pii: dev.128165. [Epub ahead of print].

An essential role for Grk2 in Hedgehog signalling downstream of Smoothened

Authors:
Zhao Z, Lee RT, Pusapati GV, Iyu A, Rohatgi R, Ingham PW
Citation:
EMBO Rep. 2016 Apr 4. pii: e201541532. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The G-protein-coupled receptor kinase 2 (adrbk2/GRK2) has been implicated in vertebrate Hedgehog (Hh) signalling based on the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Z, Lee RT, Pusapati GV, Iyu A, Rohatgi R, Ingham PW. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. EMBO Rep. 2016 Apr 4. pii: e201541532. [Epub ahead of print].

Different Modulatory Mechanisms of Renal FXYD12 for Na+-K+-ATPase between Two Closely Related Medakas upon Salinity Challenge

Authors:
Yang W-K, Kang C-K, Hsu A-D, Lin C-H, Lee T-H
Citation:
Int J Biol Sci. 2016;12(6):730-745. doi:10.7150/ijbs.15066
Epub:
Not Epub
Abstract:
Upon salinity challenge, the Na+-K+-ATPase (NKA) of fish kidney plays a crucial role in maintaining ion and water balance....
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Yang W-K, Kang C-K, Hsu A-D, Lin C-H, Lee T-H. Different Modulatory Mechanisms of Renal FXYD12 for Na+-K+-ATPase between Two Closely Related Medakas upon Salinity Challenge. Int J Biol Sci. 2016;12(6):730-745. doi:10.7150/ijbs.15066.

Laminin and Matrix metalloproteinase 11 regulate Fibronectin levels in the zebrafish myotendinous junction

Authors:
Jenkins MH, Alrowaished SS, Goody MF, Crawford BD, Henry CA
Citation:
Skeletal Muscle. 2016;6:18. doi:10.1186/s13395-016-0089-3
Epub:
Not Epub
Abstract:
Background: Remodeling of the extracellular matrix (ECM) regulates cell adhesion as well as signaling between cells and their...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jenkins MH, Alrowaished SS, Goody MF, Crawford BD, Henry CA. Laminin and Matrix metalloproteinase 11 regulate Fibronectin levels in the zebrafish myotendinous junction. Skeletal Muscle. 2016;6:18. doi:10.1186/s13395-016-0089-3.

Analyzing In Vivo Cell Migration using Cell Transplantations and Time-lapse Imaging in Zebrafish Embryos

Authors:
Giger FA, Dumortier JG, David NB
Citation:
J Vis Exp. 2016;110):e53792. doi:10.3791/53792
Epub:
Not Epub
Abstract:
Cell migration is key to many physiological and pathological conditions, including cancer metastasis. The cellular and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giger FA, Dumortier JG, David NB. Analyzing In Vivo Cell Migration using Cell Transplantations and Time-lapse Imaging in Zebrafish Embryos. J Vis Exp. 2016;110):e53792. doi:10.3791/53792.

The LIM-homeodomain transcription factor Islet2a promotes angioblast migration

Authors:
Lamont RE, Wu CY, Ryu JR, Vu W, Davari P, Sobering RE, Kennedy RM, Munsie NM, Childs SJ
Citation:
Dev Biol. 2016 Apr 25. pii: S0012-1606(16)30237-8. doi: 10.1016/j.ydbio.2016.04.019. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Angioblasts of the developing vascular system require many signaling inputs to initiate their migration, proliferation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lamont RE, Wu CY, Ryu JR, Vu W, Davari P, Sobering RE, Kennedy RM, Munsie NM, Childs SJ. The LIM-homeodomain transcription factor Islet2a promotes angioblast migration. Dev Biol. 2016 Apr 25. pii: S0012-1606(16)30237-8. doi: 10.1016/j.ydbio.2016.04.019. [Epub ahead of print].

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