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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
MicroRNA-140-5p impairs zebrafish embryonic bone development via targeting BMP-2
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Citation:
FEBS Lett. 2016 Apr 30. doi: 10.1002/1873-3468.12190. [Epub ahead of print] Epub:
Yes Abstract:
MicroRNA-140-5p (miRNA-140-5p) is important for embryonic bone development. In the present study, we found that miRNA-140-5p... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gan S, Huang Z, Liu N, Su R, Xie G, Zhong B, Zhang K, Wang S, Hu X, Zhang J, Xiang S. MicroRNA-140-5p impairs zebrafish embryonic bone development via targeting BMP-2. FEBS Lett. 2016 Apr 30. doi: 10.1002/1873-3468.12190. [Epub ahead of print]. |
Knockdown of zebrafish Nanog increases proliferation of primordial germ cells during early embryonic development
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Citation:
Dev Growth Differ. 2016 Apr 29. doi: 10.1111/dgd.12279. [Epub ahead of print] Epub:
Yes Abstract:
Nanog is a homeodomain transcription factor that plays a prominent role in maintaining the pluripotency and self-renewal... Organism or Cell Type:
zebrafish Citation Extract: Wang H, Liu Y, Ye D, Li J, Liu J, Deng F. Knockdown of zebrafish Nanog increases proliferation of primordial germ cells during early embryonic development. Dev Growth Differ. 2016 Apr 29. doi: 10.1111/dgd.12279. [Epub ahead of print]. |
Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish
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Citation:
Development. 2016 Apr 15;143(8):1328-39. doi: 10.1242/dev.132654. Epub 2016 Mar 7 Epub:
Not Epub Abstract:
Mural cells (MCs) consisting of vascular smooth muscle cells and pericytes cover the endothelial cells (ECs) to regulate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ando K, Fukuhara S, Izumi N, Nakajima H, Fukui H, Kelsh RN, Mochizuki N. Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish. Development. 2016 Apr 15;143(8):1328-39. doi: 10.1242/dev.132654. Epub 2016 Mar 7. |
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression
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Citation:
Nat Comm. 2016;7:11317. doi:15.13155/ncomms11317 Epub:
Not Epub Abstract:
Calcium signalling plays a critical role in the pathogenesis of heart failure. Here we describe a cardiac protein named... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M, German Mouse Clinic Consortium, de Angelis MH, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N. Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression. Nat Comm. 2016;7:11317. doi:15.13155/ncomms11317. |
Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides
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Citation:
PLoS ONE. 2016;11(4): e0154723. doi:10.1371/journal.pone.0154723 Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease caused by deficiency of the survival of motor... Delivery Method:
subcutaneous (s.c.) injection Organism or Cell Type:
mice Citation Extract: Lin T-L, Chen T-H, Hsu Y-Y, Cheng Y-H, Juang B-T, Jong Y-J. Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides. PLoS ONE. 2016;11(4): e0154723. doi:10.1371/journal.pone.0154723. |
Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA
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Citation:
Bioorg Med Chem Lett. 2016 Apr 11. pii: S0960-894X(16)30386-9. doi: 10.1016/j.bmcl.2016.04.025. [Epub ahead of print] Epub:
Yes Abstract:
Potential RNA targets for chemical probes and therapeutic modalities are pervasive in the transcriptome. Oligonucleotide-based... Delivery Method:
Vivo-Morpholino Citation Extract: Costales MG, Rzuczek SG, Disney MD. Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA. Bioorg Med Chem Lett. 2016 Apr 11. pii: S0960-894X(16)30386-9. doi: 10.1016/j.bmcl.2016.04.025. [Epub ahead of print]. |
The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion
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Citation:
Hepatology. 2016 Apr 26. doi: 10.1002/hep.28622. [Epub ahead of print] Epub:
Yes Abstract:
The secretin/secretin receptor (SR) axis is upregulated by proliferating cholangiocytes during cholestasis. Secretin stimulates... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Wu N, Meng F, Invernizzi P, Bernuzzi F, Venter J, Standeford H, Onori P, Marzioni M, Alvaro D, Franchitto A, Gaudio E, Glaser S, Alpini G. The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion. Hepatology. 2016 Apr 26. doi: 10.1002/hep.28622. [Epub ahead of print]. |
Developmental exposure to acetaminophen does not induce hyperactivity in zebrafish larvae
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Citation:
J Neural Transm (Vienna). 2016 Apr 26. [Epub ahead of print] Epub:
Not Epub Abstract:
First line pain relief medication during pregnancy relies nearly entirely on the over-the-counter analgesic acetaminophen,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reuter I, Knaup S, Romanos M, Lesch KP, Drepper C, Lillesaar C. Developmental exposure to acetaminophen does not induce hyperactivity in zebrafish larvae. J Neural Transm (Vienna). 2016 Apr 26. [Epub ahead of print]. |
Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner
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Citation:
Biochem Pharmacol. 2016 Apr 22. pii: S0006-2952(16)30066-1. doi: 10.1016/j.bcp.2016.04.012. [Epub ahead of print] Epub:
Yes Abstract:
6-Formylindolo[3,2-b]carbazole (FICZ) is a potent aryl hydrocarbon receptor (AHR) agonist that is efficiently metabolized by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wincent E, Kubota A, Timme-Laragy A, Jönsson ME, Hahn ME, Stegeman JJ. Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner. Biochem Pharmacol. 2016 Apr 22. pii: S0006-2952(16)30066-1. doi: 10.1016/j.bcp.2016.04.012. [Epub ahead of print]. |
sept7b is required for the differentiation of pancreatic endocrine progenitors
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Citation:
Sci Rep. 2016;6:27992. doi:10.1038/srep24992 Epub:
Not Epub Abstract:
Protection or restoration of pancreatic β-cell mass as a therapeutic treatment for type 1 diabetes requires understanding of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dash SN, Hakonen E, Ustinov J, Otonkoski T, Andersson O, Lehtonen S. sept7b is required for the differentiation of pancreatic endocrine progenitors. Sci Rep. 2016;6:27992. doi:10.1038/srep24992. |