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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis
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Citation:
Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4 Epub:
Not Epub Abstract:
Crohn's disease (CD) is associated with delayed neutrophil recruitment and bacterial clearance at sites of acute... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chew TS, O'Shea NR, Sewell GW, Oehlers SH, Mulvey CM, Crosier PS, Godovac-Zimmermann J, Bloom SL, Smith AM, Segal AW. Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis. Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4. |
Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces
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Citation:
Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30 Epub:
Not Epub Abstract:
Contact inhibition of locomotion (CIL) is the process through which cells move away from each other after cell-cell contact,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R. Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces. Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30. |
Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution
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Citation:
BMC Biol. 2015 Aug 1;13:56. doi: 10.1186/s12915-015-0165-x Epub:
Not Epub Abstract:
BACKGROUND: The functional consequences of whole genome duplications in vertebrate evolution are not fully understood. It... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW. Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution. BMC Biol. 2015 Aug 1;13:56. doi: 10.1186/s12915-015-0165-x. |
Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome
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Citation:
Dis Model Mech. 2015 Aug 1;8(8):941-55. doi: 10.1242/dmm.019059. Epub 2015 Jun 4 Epub:
Not Epub Abstract:
Mutations in ESCO2, one of two establishment of cohesion factors necessary for proper sister chromatid cohesion (SCC), cause a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Percival SM, Thomas HR, Amsterdam A, Carroll AJ, Lees JA, Yost HJ, Parant JM. Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome. Dis Model Mech. 2015 Aug 1;8(8):941-55. doi: 10.1242/dmm.019059. Epub 2015 Jun 4. |
Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos
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Citation:
PLoS One. 2015 Jul 30;10(7):e0134299. doi: 10.1371/journal.pone.0134299. eCollection 2015 Epub:
Not Epub Abstract:
DNA damage-binding protein 1 (DDB1) is a large subunit of the heterodimeric DDB complex that recognizes DNA lesions and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu Z, Holzschuh J, Driever W. Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos. PLoS One. 2015 Jul 30;10(7):e0134299. doi: 10.1371/journal.pone.0134299. eCollection 2015. |
Repeated low doses of morpholino antisense oligomer: an intermediate mouse model of spinal muscular atrophy to explore the window of therapeutic response
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Citation:
Hum Mol Genet. 2015 Aug 11. pii: ddv329. [Epub ahead of print] Epub:
Yes Abstract:
The human SMN2 transgenic mice are well-established models of spinal muscular atrophy (SMA). While the severe type I mouse... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Zhou H, Meng J, Marrosu E, Janghra N, Morgan J, Muntoni F. Repeated low doses of morpholino antisense oligomer: an intermediate mouse model of spinal muscular atrophy to explore the window of therapeutic response. Hum Mol Genet. 2015 Aug 11. pii: ddv329. [Epub ahead of print]. |
Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models
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Citation:
Sci Rep. 2015;5:12727 doi:10.1038/srep12727 Epub:
Not Epub Abstract:
Chikungunya virus (CHIKV) infection in human is associated with debilitating and persistent arthralgia and arthritis. Currently... Delivery Method:
Endo-Porter(cultures) and Vivo-Morpholino(mice) Organism or Cell Type:
cell culture: HeLa, BHK, C6/36(mosquito) and mice Citation Extract: Lam S, Chen H, Chen CK, Min N, Chu JJH. Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models. Sci Rep. 2015;5:12727 doi:10.1038/srep12727. |
Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart
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Citation:
Mol Cell Endocrinol. 2015 Jul 25. pii: S0303-7207(15)30032-0. doi: 10.1016/j.mce.2015.07.025. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Transient early-life perturbations in glucocorticoids (GC) are linked with cardiovascular disease risk in later... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wilson KS, Baily J, Tucker CS, Matrone G, Vass S, Moran C, Chapman KE, Mullins JJ, Kenyon C, Hadoke PW, Denvir MA. Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart. Mol Cell Endocrinol. 2015 Jul 25. pii: S0303-7207(15)30032-0. doi: 10.1016/j.mce.2015.07.025. [Epub ahead of print]. |
Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish
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Citation:
PLoS One. 2015 Jul 28;10(7):e0134263. doi: 10.1371/journal.pone.0134263. eCollection 2015 Epub:
Not Epub Abstract:
Carbonic anhydrase related proteins (CARPs) X and XI are highly conserved across species and are predominantly expressed in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Aspatwar A, Tolvanen ME, Ojanen MJ, Barker HR, Saralahti AK, Bäuerlein CA, Ortutay C, Pan P, Kuuslahti M, Parikka M, Rämet M, Parkkila S. Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish. PLoS One. 2015 Jul 28;10(7):e0134263. doi: 10.1371/journal.pone.0134263. eCollection 2015. |
Evolutionary rewiring of gene regulatory network linkages at divergence of the echinoid subclasses
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Citation:
PNAS USA. 2015;112(30):E4075-E4084. doi:10.1073/pnas.1509845112 Epub:
Not Epub Abstract:
This work provides direct evidence of evolutionary rewiring of gene-regulatory circuitry accompanying divergence of two... Delivery Method:
microinjection Organism or Cell Type:
Eucidaris tribuloides (sea urchin) Citation Extract: Erkenbrack EM, Davidson EH. Evolutionary rewiring of gene regulatory network linkages at divergence of the echinoid subclasses. PNAS USA. 2015;112(30):E4075-E4084. doi:10.1073/pnas.1509845112. |