You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Cationic polyelectrolyte-mediated delivery of antisense morpholino oligonucleotides for exon-skipping in vitro and in mdx mice

Authors:
Wang M, Wu B, Tucker JD, Lu P, Lu Q
Citation:
Int J Nanomedicine. 2015 Sep 3;10:5635-46. doi: 10.2147/IJN.S89910. eCollection 2015
Epub:
Not Epub
Abstract:
In this study, we investigated a series of cationic polyelectrolytes (PEs) with different size and composition for their...
Delivery Method:
polyelectrolyte
Organism or Cell Type:
mice, mdx
Citation Extract:
Wang M, Wu B, Tucker JD, Lu P, Lu Q. Cationic polyelectrolyte-mediated delivery of antisense morpholino oligonucleotides for exon-skipping in vitro and in mdx mice. Int J Nanomedicine. 2015 Sep 3;10:5635-46. doi: 10.2147/IJN.S89910. eCollection 2015.

Molecular Physiology of an Extra-renal Cl(-) Uptake Mechanism for Body Fluid Cl(-) Homeostasis

Authors:
Wang YF, Yan JJ, Tseng YC, Chen RD, Hwang PP
Citation:
Int J Biol Sci. 2015 Aug 15;11(10):1190-203. doi: 10.7150/ijbs.11737. eCollection 2015
Epub:
Not Epub
Abstract:
The development of an ion regulatory mechanism for body fluid homeostasis was an important trait for vertebrates during the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang YF, Yan JJ, Tseng YC, Chen RD, Hwang PP. Molecular Physiology of an Extra-renal Cl(-) Uptake Mechanism for Body Fluid Cl(-) Homeostasis. Int J Biol Sci. 2015 Aug 15;11(10):1190-203. doi: 10.7150/ijbs.11737. eCollection 2015.

Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor

Authors:
Mirando AC, Fang P, Williams TF, Baldor LC, Howe AK, Ebert AM, Wilkinson B, Lounsbury KM, Guo M, Francklyn CS
Citation:
Sci Rep. 2015 Aug 14;5:13160. doi: 10.1038/srep13160
Epub:
Not Epub
Abstract:
Aminoacyl-tRNA synthetases (AARSs) catalyze an early step in protein synthesis, but also regulate diverse physiological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mirando AC, Fang P, Williams TF, Baldor LC, Howe AK, Ebert AM, Wilkinson B, Lounsbury KM, Guo M, Francklyn CS. Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor. Sci Rep. 2015 Aug 14;5:13160. doi: 10.1038/srep13160.

RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1

Authors:
Ear J, Huang H, Wilson T, Tehrani Z, Lindgren A, Sung V, Laadem A, Daniel TO, Chopra R, Lin S
Citation:
Blood. 2015 Aug 13;126(7):880-90. doi: 10.1182/blood-2015-01-622522. Epub 2015 Jun 24
Epub:
Not Epub
Abstract:
Diamond-Blackfan Anemia (DBA) is a bone marrow failure disorder characterized by low red blood cell count. Mutations in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ear J, Huang H, Wilson T, Tehrani Z, Lindgren A, Sung V, Laadem A, Daniel TO, Chopra R, Lin S. RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood. 2015 Aug 13;126(7):880-90. doi: 10.1182/blood-2015-01-622522. Epub 2015 Jun 24.

RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish

Authors:
Frese KS, Meder B, Keller A, Just S, Haas J, Vogel B, Fischer S, Backes C, Matzas M, Köhler D, Benes V, Katus HA, Rottbauer W
Citation:
J Cell Sci. 2015 Aug 15;128(16):3030-40. doi: 10.1242/jcs.166850. Epub 2015 Jun 26
Epub:
Not Epub
Abstract:
Alternative splicing is one of the major mechanisms through which the proteomic and functional diversity of eukaryotes is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Frese KS, Meder B, Keller A, Just S, Haas J, Vogel B, Fischer S, Backes C, Matzas M, Köhler D, Benes V, Katus HA, Rottbauer W. RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish. J Cell Sci. 2015 Aug 15;128(16):3030-40. doi: 10.1242/jcs.166850. Epub 2015 Jun 26.

β-Arrestin1 Regulates Morphology and Dynamics of Microglia in Zebrafish in Vivo

Authors:
Li Y, Du X, Pei G, Du J, Zhao J
Citation:
Eur J Neurosci. 2015 Sep 10. doi: 10.1111/ejn.13065. [Epub ahead of print]
Epub:
Yes
Abstract:
Microglia are the primary immune cells in the central nervous system. Microglia typically exist in a "resting" state...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Du X, Pei G, Du J, Zhao J. β-Arrestin1 Regulates Morphology and Dynamics of Microglia in Zebrafish in Vivo. Eur J Neurosci. 2015 Sep 10. doi: 10.1111/ejn.13065. [Epub ahead of print].

Two novel COLVI long chains in zebrafish that are essential for muscle development

Authors:
Ramanoudjame L, Rocancourt C, Lainé J, Klein A, Joassard L, Gartioux C, Fleury M, Lyphout L, Kabashi E, Ciura S, Cousin X, Allamand V
Citation:
Hum Mol Genet. 2015 Sep 11. pii: ddv368. [Epub ahead of print]
Epub:
Yes
Abstract:
Collagen VI (COLVI), a protein ubiquitously expressed in connective tissues, is crucial for structural integrity, cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ramanoudjame L, Rocancourt C, Lainé J, Klein A, Joassard L, Gartioux C, Fleury M, Lyphout L, Kabashi E, Ciura S, Cousin X, Allamand V. Two novel COLVI long chains in zebrafish that are essential for muscle development. Hum Mol Genet. 2015 Sep 11. pii: ddv368. [Epub ahead of print].

ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning

Authors:
Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV
Citation:
Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023
Epub:
Not Epub
Abstract:
The ciliary kinase NEK8 plays a critical role in situs determination and cystic kidney disease, yet its exact function remains...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV. ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023.

TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells

Authors:
Yarosh CA, Tapescu I, Thompson MG, Qiu J, Mallory MJ, Fu XD, Lynch KW
Citation:
Nucleic Acids Res. 2015 Aug 10. pii: gkv816. [Epub ahead of print]
Epub:
Yes
Abstract:
PSF (a.k.a. SFPQ) is a ubiquitously expressed, essential nuclear protein with important roles in DNA damage repair and RNA...
Organism or Cell Type:
cell culture: JSL1 cells
Citation Extract:
Yarosh CA, Tapescu I, Thompson MG, Qiu J, Mallory MJ, Fu XD, Lynch KW. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Res. 2015 Aug 10. pii: gkv816. [Epub ahead of print].

Luminal signalling links cell communication to tissue architecture during organogenesis

Authors:
Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, Schwab Y, Gilmour D
Citation:
Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22
Epub:
Not Epub
Abstract:
Morphogenesis is the process whereby cell collectives are shaped into differentiated tissues and organs. The self-organizing...
Citation Extract:
Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, Schwab Y, Gilmour D. Luminal signalling links cell communication to tissue architecture during organogenesis. Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22.

Pages