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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A cationic morpholino antisense oligomer conjugate: synthesis, cellular uptake and inhibition of Gli1 in the hedgehog signalling pathway
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Citation:
RSC Adv. 2014. 4:1951-1954. doi:10.1039/C3RA45257C Epub:
Not Epub Abstract:
A guanidinium-linked morpholino pentamer is synthesized and evaluated for cellular penetration properties. A regular morpholino... Organism or Cell Type:
cell culture Citation Extract: Pattanayak S, Khatra H, Sahab S, Sinha S. A cationic morpholino antisense oligomer conjugate: synthesis, cellular uptake and inhibition of Gli1 in the hedgehog signalling pathway. RSC Adv. 2014. 4:1951-1954. doi:10.1039/C3RA45257C . |
Synthesis of morpholino monomers, chlorophosphoramidate monomers, and solid-phase synthesis of short morpholino oligomers
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Citation:
Curr Protoc Nucleic Acid Chem. 2015;62:4.65.1-4.65.26. doi: 10.1002/0471142700.nc0465s62 Epub:
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Phosphorodiamidate morpholino oligomers (PMOs) are a highly capable class of synthetic antisense oligonucleotides that are used... Citation Extract: Bhadra J, Pattanayak S, Sinha S. Synthesis of morpholino monomers, chlorophosphoramidate monomers, and solid-phase synthesis of short morpholino oligomers. Curr Protoc Nucleic Acid Chem. 2015;62:4.65.1-4.65.26. doi: 10.1002/0471142700.nc0465s62. |
DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome
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Citation:
J Clin Invest. 2015 Sep 1;125(9):3657-66. doi: 10.1172/JCI80657. Epub 2015 Aug 24 Epub:
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Juvenile ciliopathy syndromes that are associated with renal cysts and premature renal failure are commonly the result of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Slaats GG, Saldivar JC, Bacal J, Zeman MK, Kile AC, Hynes AM, Srivastava S, Nazmutdinova J, Ouden Kd, Zagers MS, Foletto V, Verhaar MC, Miles C, Sayer JA, Cimprich KA, Giles RH. DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome. J Clin Invest. 2015 Sep 1;125(9):3657-66. doi: 10.1172/JCI80657. Epub 2015 Aug 24. |
TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy
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Citation:
Cell Rep. 2015 Sep 8;12(10):1678-90. doi: 10.1016/j.celrep.2015.07.066. Epub 2015 Aug 28 Epub:
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The amount and distribution of dystrophin protein in myofibers and muscle is highly variable in Becker muscular dystrophy and... Delivery Method:
injection Organism or Cell Type:
mice, mdx Citation Extract: Fiorillo AA, Heier CR, Novak JS, Tully CB, Brown KJ, Uaesoontrachoon K, Vila MC, Ngheim PP, Bello L, Kornegay JN, Angelini C, Partridge TA, Nagaraju K, Hoffman EP. TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy. Cell Rep. 2015 Sep 8;12(10):1678-90. doi: 10.1016/j.celrep.2015.07.066. Epub 2015 Aug 28. |
An equation to estimate the difference between theoretically predicted and SDS PAGE-displayed molecular weights for an acidic peptide
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Citation:
Sci Rep. 2015 Aug 27;5:13370. doi: 10.1038/srep13370 Epub:
Not Epub Abstract:
The molecular weight (MW) of a protein can be predicted based on its amino acids (AA) composition. However, in many cases a non... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guan Y, Zhu Q, Huang D, Zhao S, Jan Lo L, Peng J. An equation to estimate the difference between theoretically predicted and SDS PAGE-displayed molecular weights for an acidic peptide. Sci Rep. 2015 Aug 27;5:13370. doi: 10.1038/srep13370. |
Telomerase Is Essential for Zebrafish Heart Regeneration
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Citation:
Cell Rep. 2015 Sep 8;12(10):1691-703. doi: 10.1016/j.celrep.2015.07.064. Epub 2015 Aug 28 Epub:
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After myocardial infarction in humans, lost cardiomyocytes are replaced by an irreversible fibrotic scar. In contrast,... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Bednarek D, González-Rosa JM, Guzmán-Martínez G, Gutiérrez-Gutiérrez Ó, Aguado T, Sánchez-Ferrer C, Marques IJ, Galardi-Castilla M, de Diego I, Gómez MJ, Cortés A, Zapata A, Jiménez-Borreguero LJ, Mercader N, Flores I. Telomerase Is Essential for Zebrafish Heart Regeneration. Cell Rep. 2015 Sep 8;12(10):1691-703. doi: 10.1016/j.celrep.2015.07.064. Epub 2015 Aug 28. |
Transcriptome analysis of severe hypoxic stress during development in zebrafish
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Citation:
Genomics Data. 2015;6:83-88. doi:10.1016/j.gdata.2015.07.025 Epub:
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Hypoxia causes critical cellular injury both in early human development and in adulthood, leading to cerebral palsy, stroke,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Woods IG, Imam FB. Transcriptome analysis of severe hypoxic stress during development in zebrafish. Genomics Data. 2015;6:83-88. doi:10.1016/j.gdata.2015.07.025. |
Polyamine biosynthesis is critical for growth and differentiation of the pancreas
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Citation:
Sci Rep. 2015 Aug 24;5:13269. doi: 10.1038/srep13269 Epub:
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The pancreas, in most studied vertebrates, is a compound organ with both exocrine and endocrine functions. The exocrine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mastracci TL, Robertson MA, Mirmira RG, Anderson RM. Polyamine biosynthesis is critical for growth and differentiation of the pancreas. Sci Rep. 2015 Aug 24;5:13269. doi: 10.1038/srep13269. |
Chamber identity programs drive early functional partitioning of the heart
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Citation:
Nat Commun. 2015 Aug 26;6:8146. doi: 10.1038/ncomms9146 Epub:
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The vertebrate heart muscle (myocardium) develops from the first heart field (FHF) and expands by adding second heart field (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mosimann C, Panáková D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, Zon LI. Chamber identity programs drive early functional partitioning of the heart. Nat Commun. 2015 Aug 26;6:8146. doi: 10.1038/ncomms9146. |
Antisense Morpholino Oligonucleotides Reduce Neurofilament Synthesis and Inhibit Axon Regeneration in Lamprey Reticulospinal Neurons
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Citation:
PLoS One. 2015 Sep 14;10(9):e0137670. doi: 10.1371/journal.pone.0137670. eCollection 2015 Epub:
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The sea lamprey has been used as a model for the study of axonal regeneration after spinal cord injury. Previous studies have... Delivery Method:
gelfoam at lesion Organism or Cell Type:
Petromyzon marinus (sea lamprey) Citation Extract: Zhang G, Jin LQ, Hu J, Rodemer W, Selzer ME. Antisense Morpholino Oligonucleotides Reduce Neurofilament Synthesis and Inhibit Axon Regeneration in Lamprey Reticulospinal Neurons. PLoS One. 2015 Sep 14;10(9):e0137670. doi: 10.1371/journal.pone.0137670. eCollection 2015. |