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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish

Authors:
Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF
Citation:
PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (ASOs) are synthetic, single-strand RNA-DNA hybrids that induce catalytic degradation of...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139504
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF. Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015.

Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?

Authors:
Kruszka P, Uwineza A, Mutesa L, Martinez AF, Abe Y, Zackai EH, Ganetzky R, Chung B, Stevenson RE, Adelstein RS, Ma X, Mullikin JC, Hong SK, Muenke M
Citation:
Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6
Epub:
Not Epub
Abstract:
Limb body wall complex (LBWC) and amniotic band sequence (ABS) are multiple congenital anomaly conditions with craniofacial,...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/mgg3.153/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Kruszka P, Uwineza A, Mutesa L, Martinez AF, Abe Y, Zackai EH, Ganetzky R, Chung B, Stevenson RE, Adelstein RS, Ma X, Mullikin JC, Hong SK, Muenke M. Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?. Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6.

Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β

Authors:
Macaulay LJ, Chen A, Rock KD, Dishaw LV, Dong W, Hinton DE, Stapleton HM
Citation:
Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print]
Epub:
Not Epub
Abstract:
6-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) is both a polybrominated diphenyl ether (PBDE) flame...
Link:
http://www.sciencedirect.com/science/article/pii/S0166445X15300473
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Macaulay LJ, Chen A, Rock KD, Dishaw LV, Dong W, Hinton DE, Stapleton HM. Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β. Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print].

Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish

Authors:
Hung FC, Shih HY, Cheng YC, Chao C
Citation:
Stem Cells Dev. 2015 Sep 28. [Epub ahead of print]
Epub:
Yes
Abstract:
Growth-arrest-specific 7 (Gas7) is preferentially expressed in the nervous system and plays an important role during...
Link:
http://online.liebertpub.com/doi/10.1089/scd.2015.0146
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung FC, Shih HY, Cheng YC, Chao C. Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish. Stem Cells Dev. 2015 Sep 28. [Epub ahead of print].

Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome

Authors:
Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N
Citation:
Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print]
Epub:
Yes
Abstract:
The nuclear pore complex (NPC) is a huge protein complex embedded in the nuclear envelope. It has central functions in...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2815%2900363-8
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N. Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome. Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print].

Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II

Authors:
Matos L, Gonçalves V, Pinto E, Laranjeira F, Prata MJ, Jordan P, Desviat LR, Pérez B, Alves S
Citation:
Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print]
Epub:
Yes
Abstract:
Mucopolysaccharidosis II is a lysosomal storage disorder caused by mutations in the IDS gene, including exonic alterations...
Link:
http://www.sciencedirect.com/science/article/pii/S0925443915002835
Organism or Cell Type:
cell culture: human primary cells
Citation Extract:
Matos L, Gonçalves V, Pinto E, Laranjeira F, Prata MJ, Jordan P, Desviat LR, Pérez B, Alves S. Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II. Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print].

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

Authors:
Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO
Citation:
Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391
Epub:
Not Epub
Abstract:
Membrane proteins are crucial to heart function and development. Here we combine cationic silica-bead coating with shotgun...
Link:
http://www.nature.com/ncomms/2015/150925/ncomms9391/full/ncomms9391.html
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391.

HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish

Authors:
He Y, Wang Z, Sun S, Tang D, Li W, Chai R, Li H
Citation:
Mol Neurobiol. 2015 Sep 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Histone deacetylases (HDACs) are involved in multiple developmental processes, but their functions in the development of...
Link:
http://link.springer.com/article/10.1007%2Fs12035-015-9433-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He Y, Wang Z, Sun S, Tang D, Li W, Chai R, Li H. HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish. Mol Neurobiol. 2015 Sep 22. [Epub ahead of print].

Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas

Authors:
Won M, Ro H, Dawid IB
Citation:
Proc Natl Acad Sci U S A. 2015 Sep 21. pii: 201517033. [Epub ahead of print]
Epub:
Yes
Abstract:
The gene encoding the E3 ubiquitin ligase Ligand of Numb protein-X (Lnx)2a is expressed in the ventral-anterior pancreatic bud...
Link:
http://www.pnas.org/content/early/2015/09/17/1517033112.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Won M, Ro H, Dawid IB. Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas. Proc Natl Acad Sci U S A. 2015 Sep 21. pii: 201517033. [Epub ahead of print].

The Role of ARF6 in Biliary Atresia

Authors:
Ningappa M, So J, Glessner J, Ashokkumar C, Ranganathan S, Min J, Higgs BW, Sun Q, Haberman K, Schmitt L, Vilarinho S, Mistry PK, Vockley G, Dhawan A, Gittes GK, Hakonarson H, Jaffe R, Subramaniam S, Shin D, Sindhi R
Citation:
PLoS One. 2015 Sep 17;10(9):e0138381. doi: 10.1371/journal.pone.0138381. eCollection 2015
Epub:
Not Epub
Abstract:
BACKGROUND & AIMS: Altered extrahepatic bile ducts, gut, and cardiovascular anomalies constitute the variable phenotype of...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138381
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ningappa M, So J, Glessner J, Ashokkumar C, Ranganathan S, Min J, Higgs BW, Sun Q, Haberman K, Schmitt L, Vilarinho S, Mistry PK, Vockley G, Dhawan A, Gittes GK, Hakonarson H, Jaffe R, Subramaniam S, Shin D, Sindhi R. The Role of ARF6 in Biliary Atresia. PLoS One. 2015 Sep 17;10(9):e0138381. doi: 10.1371/journal.pone.0138381. eCollection 2015.

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