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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Knockdown of Tmem234 in zebrafish results in proteinuria

Authors:
Rodriguez PQ, Oddsson A, Ebarasi L, He B, Hultenby K, Wernerson A, Betsholtz C, Tryggvason K, Patrakka J
Citation:
Am J Physiol Renal Physiol. 2015 Sep 16:ajprenal.00525.2014. doi: 10.1152/ajprenal.00525.2014. [Epub ahead of print]
Epub:
Yes
Abstract:
Podocytes are highly specialized epithelial cells located at the outer aspects of the glomerular capillary tuft and critical...
Link:
http://ajprenal.physiology.org/content/early/2015/09/10/ajprenal.00525.2014
Organism or Cell Type:
zebrafish
Citation Extract:
Rodriguez PQ, Oddsson A, Ebarasi L, He B, Hultenby K, Wernerson A, Betsholtz C, Tryggvason K, Patrakka J. Knockdown of Tmem234 in zebrafish results in proteinuria. Am J Physiol Renal Physiol. 2015 Sep 16:ajprenal.00525.2014. doi: 10.1152/ajprenal.00525.2014. [Epub ahead of print].

Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish

Authors:
Liu F, Xia W, Hu J, Wang Y, Yang F, Sun S, Zhang J, Jiang N, Wang H, Tian W, Wang X, Ma D
Citation:
PLoS One. 2015 Sep 16;10(9):e0136832. doi: 10.1371/journal.pone.0136832. eCollection 2015
Epub:
Not Epub
Abstract:
Hearing loss is one of the most prevalent human birth defects. Genetic factors contribute to the pathogenesis of deafness. It...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136832
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu F, Xia W, Hu J, Wang Y, Yang F, Sun S, Zhang J, Jiang N, Wang H, Tian W, Wang X, Ma D. Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish. PLoS One. 2015 Sep 16;10(9):e0136832. doi: 10.1371/journal.pone.0136832. eCollection 2015.

Spiroindolone That Inhibits PfATPase4 Is a Potent, Cidal Inhibitor of Toxoplasma gondii Tachyzoites In Vitro and In Vivo

Authors:
Zhou Y, Fomovska A, Muench S, Lai BS, Mui E, McLeod R
Citation:
Antimicrob Agents Chemother. 2014;58(3):1789-92. doi: 10.1128/AAC.02225-13. Epub 2013 Dec 23. PMID: 24366743
Epub:
Not Epub
Abstract:
Here, we show that spiroindolone, an effective treatment for plasmodia, is also active against Toxoplasma gondii tachyzoites....
Link:
http://aac.asm.org/content/early/2013/12/17/AAC.02225-13.abstract
Delivery Method:
peptide-linked
Organism or Cell Type:
Toxoplasma gondii
Citation Extract:
Zhou Y, Fomovska A, Muench S, Lai BS, Mui E, McLeod R. Spiroindolone That Inhibits PfATPase4 Is a Potent, Cidal Inhibitor of Toxoplasma gondii Tachyzoites In Vitro and In Vivo. Antimicrob Agents Chemother. 2014;58(3):1789-92. doi: 10.1128/AAC.02225-13. Epub 2013 Dec 23. PMID: 24366743 .

Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia

Authors:
Symoens S, Barnes AM, Gistelinck C, Malfait F, Guillemyn B, Steyaert W, Syx D, D'hondt S, Biervliet M, De Backer J, Witten EP, Leikin S, Makareeva E, Gillessen-Kaesbach G, Huysseune A, Vleminckx K, Willaert A, De Paepe A, Marini JC, Coucke PJ
Citation:
Am J Hum Genet. 2015 Sep 9. pii: S0002-9297(15)00331-6. doi: 10.1016/j.ajhg.2015.08.009. [Epub ahead of print]
Epub:
Yes
Abstract:
The evolutionarily conserved transmembrane anterior posterior transformation 1 protein, encoded by TAPT1, is involved in murine...
Link:
http://www.sciencedirect.com/science/article/pii/S0002929715003316
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Symoens S, Barnes AM, Gistelinck C, Malfait F, Guillemyn B, Steyaert W, Syx D, D'hondt S, Biervliet M, De Backer J, Witten EP, Leikin S, Makareeva E, Gillessen-Kaesbach G, Huysseune A, Vleminckx K, Willaert A, De Paepe A, Marini JC, Coucke PJ. Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia. Am J Hum Genet. 2015 Sep 9. pii: S0002-9297(15)00331-6. doi: 10.1016/j.ajhg.2015.08.009. [Epub ahead of print].

Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation

Authors:
Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE
Citation:
Stem Cell Reports. 2015 Sep 9. pii: S2213-6711(15)00244-1. doi: 10.1016/j.stemcr.2015.08.010. [Epub ahead of print]
Epub:
Yes
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) are born from hemogenic endothelium in the dorsal aorta. Specification of this...
Link:
http://www.cell.com/stem-cell-reports/abstract/S2213-6711%2815%2900244-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Stem Cell Reports. 2015 Sep 9. pii: S2213-6711(15)00244-1. doi: 10.1016/j.stemcr.2015.08.010. [Epub ahead of print].

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

Authors:
Lu Q, Insinna C, Ott C, Stauffer J, Pintado PA, Rahajeng J, Baxa U, Walia V, Cuenca A, Hwang YS, Daar IO, Lopes S, Lippincott-Schwartz J, Jackson PK, Caplan S, Westlake CJ
Citation:
Nat Cell Biol. 2015 Mar;17(3):228-40. doi: 10.1038/ncb3109. Epub 2015 Feb 16. Erratum in: Nat Cell Biol. 2015 Apr;17(4):531
Epub:
Not Epub
Abstract:
Membrane association with mother centriole (M-centriole) distal appendages is critical for ciliogenesis initiation. How the Rab...
Link:
http://www.nature.com/ncb/journal/v17/n3/full/ncb3109.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu Q, Insinna C, Ott C, Stauffer J, Pintado PA, Rahajeng J, Baxa U, Walia V, Cuenca A, Hwang YS, Daar IO, Lopes S, Lippincott-Schwartz J, Jackson PK, Caplan S, Westlake CJ. Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation. Nat Cell Biol. 2015 Mar;17(3):228-40. doi: 10.1038/ncb3109. Epub 2015 Feb 16. Erratum in: Nat Cell Biol. 2015 Apr;17(4):531.

Yap and Taz regulate retinal pigment epithelial cell fate

Authors:
Miesfeld JB, Gestri G, Clark BS, Flinn MA, Poole RJ, Bader JR, Besharse JC, Wilson SW, Link BA
Citation:
Development. 2015 Sep 1;142(17):3021-32. doi: 10.1242/dev.119008. Epub 2015 Jul 24
Epub:
Not Epub
Abstract:
The optic vesicle comprises a pool of bi-potential progenitor cells from which the retinal pigment epithelium (RPE) and neural...
Link:
http://dev.biologists.org/content/142/17/3021.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miesfeld JB, Gestri G, Clark BS, Flinn MA, Poole RJ, Bader JR, Besharse JC, Wilson SW, Link BA. Yap and Taz regulate retinal pigment epithelial cell fate. Development. 2015 Sep 1;142(17):3021-32. doi: 10.1242/dev.119008. Epub 2015 Jul 24.

Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

Authors:
Agarwala S, Duquesne S, Liu K, Boehm A, Grimm L, Link S, König S, Eimer S, Ronneberger O, Lecaudey V
Citation:
Elife. 2015 Sep 3;4. doi: 10.7554/eLife.08201. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During development, proliferation must be tightly controlled for organs to reach their appropriate size. While the Hippo...
Link:
http://elifesciences.org/content/elife/early/2015/09/03/eLife.08201.full.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Agarwala S, Duquesne S, Liu K, Boehm A, Grimm L, Link S, König S, Eimer S, Ronneberger O, Lecaudey V. Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish. Elife. 2015 Sep 3;4. doi: 10.7554/eLife.08201. [Epub ahead of print].

The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo

Authors:
Haillot E, Molina MD, Lapraz F, Lepage T
Citation:
PLoS Biol. 2015 Sep 9;13(9):e1002247. doi: 10.1371/journal.pbio.1002247. eCollection 2015 Sep
Epub:
Not Epub
Abstract:
Specification of the dorsal-ventral axis in the highly regulative sea urchin embryo critically relies on the zygotic expression...
Link:
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002247
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Haillot E, Molina MD, Lapraz F, Lepage T. The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo. PLoS Biol. 2015 Sep 9;13(9):e1002247. doi: 10.1371/journal.pbio.1002247. eCollection 2015 Sep.

Panorama of ancient metazoan macromolecular complexes

Authors:
Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, R Tillier E, Wallingford JB, Parkinson J, Marcotte EM, Emili A
Citation:
Nature. 2015 Sep 7. doi: 10.1038/nature14877. [Epub ahead of print]
Epub:
Yes
Abstract:
Macromolecular complexes are essential to conserved biological processes, but their prevalence across animals is unclear. By...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14877.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, R Tillier E, Wallingford JB, Parkinson J, Marcotte EM, Emili A. Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 7. doi: 10.1038/nature14877. [Epub ahead of print].

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