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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Extraembryonic Signals under the Control of MGA, Max, and Smad4 Are Required for Dorsoventral Patterning

Authors:
Sun Y, Tseng W-C, Fan X, Ball R, Dougan ST
Citation:
Dev Cell. 2014;28(3):322-334
Epub:
Not Epub
Abstract:
In vertebrates, extraembryonic tissues can act as signaling centers that impose a reproducible pattern of cell types upon the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Tseng W-C, Fan X, Ball R, Dougan ST. Extraembryonic Signals under the Control of MGA, Max, and Smad4 Are Required for Dorsoventral Patterning. Dev Cell. 2014;28(3):322-334.

Survivin-Induced Abnormal Ploidy Contributes to Cystic Kidney and Aneurysm Formation

Authors:
Aboualaiwi WA, Muntean BS, Ratnam S, Joe B, Liu L, Booth RL, Rodriguez I, Herbert BS, Bacallao RL, Fruttiger M, Mak TW, Zhou J, Nauli SM
Citation:
Circulation. 2014;129:660-672
Epub:
Not Epub
Abstract:
BACKGROUND: Cystic kidneys and vascular aneurysms are clinical manifestations seen in patients with polycystic kidney disease (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aboualaiwi WA, Muntean BS, Ratnam S, Joe B, Liu L, Booth RL, Rodriguez I, Herbert BS, Bacallao RL, Fruttiger M, Mak TW, Zhou J, Nauli SM. Survivin-Induced Abnormal Ploidy Contributes to Cystic Kidney and Aneurysm Formation. Circulation. 2014;129:660-672 .

Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia

Authors:
Khandanpour C, Phelan JD, Vassen L, Schütte J, Chen R, Horman SR, Gaudreau MC, Krongold J, Zhu J, Paul WE, Dührsen U, Göttgens B, Grimes HL, Möröy T
Citation:
Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011
Epub:
Not Epub
Abstract:
Most patients with acute lymphoblastic leukemia (ALL) fail current treatments highlighting the need for better therapies....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Khandanpour C, Phelan JD, Vassen L, Schütte J, Chen R, Horman SR, Gaudreau MC, Krongold J, Zhu J, Paul WE, Dührsen U, Göttgens B, Grimes HL, Möröy T. Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia. Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011.

Electrophysiological Biomarkers in Spinal Muscular Atrophy: Preclinical Proof of Concept

Authors:
Arnold WD, Porensky PN, McGovern VL, Iyer CC, Duque S, Li X, Meyer K, Schmelzer L, Kaspar BK, Kolb SJ, Kissel JT, Burghes AH
Citation:
Ann Clin Transl Neurol. 2014 Jan 1;1(1):34-44
Epub:
Not Epub
Abstract:
Objective: Preclinical therapies that restore survival motor neuron (SMN) protein levels can dramatically extend survival in...
Delivery Method:
intracerebroventricular injection
Organism or Cell Type:
mouse
Citation Extract:
Arnold WD, Porensky PN, McGovern VL, Iyer CC, Duque S, Li X, Meyer K, Schmelzer L, Kaspar BK, Kolb SJ, Kissel JT, Burghes AH. Electrophysiological Biomarkers in Spinal Muscular Atrophy: Preclinical Proof of Concept. Ann Clin Transl Neurol. 2014 Jan 1;1(1):34-44.

A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish

Authors:
Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML
Citation:
Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228
Epub:
Not Epub
Abstract:
Dyskeratosis congenita (DC) is an inherited disorder with mutations affecting telomerase or telomeric proteins. DC patients...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML. A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228.

PCP and septins compartmentalize cortical actomyosin to direct collective cell movement

Authors:
Shindo A, Wallingford JB
Citation:
Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126
Epub:
Not Epub
Abstract:
Despite our understanding of actomyosin function in individual migrating cells, we know little about the mechanisms by which...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shindo A, Wallingford JB. PCP and septins compartmentalize cortical actomyosin to direct collective cell movement. Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126.

An essential role for LPA signalling in telencephalon development

Authors:
Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L
Citation:
Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901
Epub:
Not Epub
Abstract:
Lysophosphatidic acid (LPA) has wide-ranging effects on many different cell types, acting through G-protein-coupled receptors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L. An essential role for LPA signalling in telencephalon development. Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901.

Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure

Authors:
Fero K, Bergeron SA, Horstick EJ, Codore H, Li GH, Ono F, Dowling JJ, Burgess HA
Citation:
Dis Model Mech. 2013 Nov 7. [Epub ahead of print]
Epub:
Yes
Abstract:
An essential step in muscle fiber maturation is the assembly of highly ordered myofibrils that are required for contraction....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fero K, Bergeron SA, Horstick EJ, Codore H, Li GH, Ono F, Dowling JJ, Burgess HA. Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure. Dis Model Mech. 2013 Nov 7. [Epub ahead of print].

PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos

Authors:
Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J
Citation:
BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print]
Epub:
Yes
Abstract:
During Xenopus early development, FGF signaling is involved in mesoderm formation and neurogenesis by modulating various...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J. PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos. BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print].

Differential Skeletal Muscle Proteome of High and Low Active mice

Authors:
Ferguson DP, Dangott LJ, Schmitt EE, Vellers HL, Lightfoot JT
Citation:
J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print]
Epub:
Yes
Abstract:
Physical inactivity contributes to cardiovascular disease, type II diabetes, obesity and some types of cancer. While the...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Ferguson DP, Dangott LJ, Schmitt EE, Vellers HL, Lightfoot JT. Differential Skeletal Muscle Proteome of High and Low Active mice. J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print].

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