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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo
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Citation:
J Biochem. 2014 Jan 21. [Epub ahead of print] Epub:
Yes Abstract:
Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are second-generation lysophospholipid mediators that exert... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J. Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. J Biochem. 2014 Jan 21. [Epub ahead of print]. |
The Nogo-C2/Nogo Receptor Complex Regulates the Morphogenesis of Zebrafish Lateral Line Primordium through Modulating the Expression of dkk1b, a Wnt Signal Inhibitor
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Citation:
PLoS ONE. 2014;9(1):e86345. doi:10.1371/journal.pone.0086345 Epub:
Not Epub Abstract:
The fish lateral line (LL) is a mechanosensory system closely related to the hearing system of higher vertebrates, and it is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Han H-W, Chou C-M, Chu C-Y, Cheng C-H, Yang C-H, Hung C-C, Hwang P-P, Lee S-J, Liao Y-F, Huang C-J. The Nogo-C2/Nogo Receptor Complex Regulates the Morphogenesis of Zebrafish Lateral Line Primordium through Modulating the Expression of dkk1b, a Wnt Signal Inhibitor. PLoS ONE. 2014;9(1):e86345. doi:10.1371/journal.pone.0086345. |
Zebrafish eaf1 Suppresses foxo3b Expression to Modulate Transcriptional Activity of gata1 and spi1 in Primitive Hematopoiesis
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Citation:
Dev Biol. 2014 Apr 1;388(1):81-93. doi: 10.1016/j.ydbio.2014.01.005. Epub 2014 Jan 17 Epub:
Not Epub Abstract:
Studies implicate a potential role for EAF1 in MLL-ELL induced leukemogenesis; however the biological function of EAF1 in this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu B, Zhang W, Feng X, Ji W, Xie X, Xiao W. Zebrafish eaf1 Suppresses foxo3b Expression to Modulate Transcriptional Activity of gata1 and spi1 in Primitive Hematopoiesis. Dev Biol. 2014 Apr 1;388(1):81-93. doi: 10.1016/j.ydbio.2014.01.005. Epub 2014 Jan 17. |
Endocytosis of Fgf8 Is a Double-Stage Process and Regulates Spreading and Signaling
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Citation:
PLoS ONE. 2014;9(1):e86373. doi:10.1371/journal.pone.0086373 Epub:
Not Epub Abstract:
Tightly controlled concentration gradients of morphogens provide positional information and thus regulate tissue... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rengarajan C, Matzke A, Reiner L, Orian-Rousseau V, Scholpp S. Endocytosis of Fgf8 Is a Double-Stage Process and Regulates Spreading and Signaling. PLoS ONE. 2014;9(1):e86373. doi:10.1371/journal.pone.0086373. |
Autophagy is essential for cardiac morphogenesis during vertebrate development
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Citation:
Autophagy. 2014 Jan 14;10(4). [Epub ahead of print] Epub:
Not Epub Abstract:
Genetic analyses indicate that autophagy, an evolutionarily conserved lysosomal degradation pathway, is essential for... Organism or Cell Type:
zebrafish Citation Extract: Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF. Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 2014 Jan 14;10(4). [Epub ahead of print]. |
Hoxb1b controls oriented cell division, cell shape and microtubule dynamics in neural tube morphogenesis
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Citation:
Development. 2014;141:639-649. doi:10.1242/dev.098731 Epub:
Not Epub Abstract:
Hox genes are classically ascribed to function in patterning the anterior-posterior axis of bilaterian animals; however, their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Žigman M, Laumann-Lipp N, Titus T, Postlethwait J, Moens CB. Hoxb1b controls oriented cell division, cell shape and microtubule dynamics in neural tube morphogenesis. Development. 2014;141:639-649. doi:10.1242/dev.098731 . |
Transgenic Zebrafish Reveal Tissue-Specific Differences in Estrogen Signaling in Response to Environmental Water Samples
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Citation:
Environ Health Perspect. 2014;122(4):356-62 doi:0.1289/ehp.1307329 Epub:
Not Epub Abstract:
Background: Environmental endocrine disruptors (EED) are exogenous chemicals that mimic endogenous hormones, such as estrogens... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gorelick DA, Iwanowicz LR, Hung AL, Blazer VS, Halpern ME. Transgenic Zebrafish Reveal Tissue-Specific Differences in Estrogen Signaling in Response to Environmental Water Samples. Environ Health Perspect. 2014;122(4):356-62 doi:0.1289/ehp.1307329. |
Bubble Liposomes and Ultrasound Exposure Improve Localized Morpholino Oligomer Delivery into the Skeletal Muscles of Dystrophic mdx Mice
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Citation:
Molec Pharmaceutics. 2014;[epub ahead of print] doi:10.1021/mp4004755 Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a genetic disorder that is caused by mutations in the DMD gene that lead to an absence of... Delivery Method:
bubble liposomes & ultrasound Organism or Cell Type:
mice, mdx Citation Extract: Negishi Y, Ishii Y, Shiono H, Akiyama S, Sekine S, Kojima T, Mayama S, Kikuchi T, Hamano N, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y. Bubble Liposomes and Ultrasound Exposure Improve Localized Morpholino Oligomer Delivery into the Skeletal Muscles of Dystrophic mdx Mice. Molec Pharmaceutics. 2014;[epub ahead of print] doi:10.1021/mp4004755. |
Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish
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Citation:
Nat Commun. 2014 Jan 16;5:3153. doi: 10.1038/ncomms4153 Epub:
Not Epub Abstract:
The T-box transcription factor Tbx5 (Tbx5a in zebrafish) plays a crucial role in the formation of cardiac chambers in a dose-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tong X, Zu Y, Li Z, Li W, Ying L, Yang J, Wang X, He S, Liu D, Zhu Z, Chen J, Lin S, Zhang B. Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish. Nat Commun. 2014 Jan 16;5:3153. doi: 10.1038/ncomms4153. |
Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice and zebrafish
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Citation:
Blood. 2013 Nov 6. [Epub ahead of print] Epub:
Yes Abstract:
Neutrophil (PMN) lifespan and function are regulated by hypoxia, via components of the HIF/VHL/hydroxylase pathway, including... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Thompson AA, Elks PM, Marriott HM, Eamsamarng S, Higgins KR, Lewis A, Williams L, Parmar S, Shaw G, McGrath EE, Formenti F, Van Eeden FJ, Kinnula VL, Pugh CW, Sabroe I, Dockrell DH, Chilvers ER, Robbins PA, Percy MJ, Simon MC, Johnson RS, Renshaw SA, Whyte MK, Walmsley SR. Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice and zebrafish. Blood. 2013 Nov 6. [Epub ahead of print]. |