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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy
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Citation:
PLoS ONE. 2013;8(11):e80263. doi:10.1371/journal.pone.0080263 Epub:
Not Epub Abstract:
Duchenne muscular Dystrophy (DMD) is an inherited disease caused by mutations in the dystrophin gene that disrupt the open... Delivery Method:
i.v. infusion Organism or Cell Type:
Human - clinical trials Citation Extract: Zaharieva IT, Calissano M, Scoto M, Preston M, Cirak S, Feng L, Collins J, Kole R, Guglieri M, Straub V, Bushby K, Ferlini A, Morgan JE, Muntoni F. Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy. PLoS ONE. 2013;8(11):e80263. doi:10.1371/journal.pone.0080263. |
A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis
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Citation:
PLoS ONE. 2013;8(11):e80823. doi:10.1371/journal.pone.0080823 Epub:
Not Epub Abstract:
Albinism, the loss of melanin pigmentation, has evolved in a diverse variety of cave animals but the responsible evolutionary... Delivery Method:
microinjection Organism or Cell Type:
Astyanax mexicanus Citation Extract: Bilandžija H, Ma L, Parkhurst A, Jeffery WR. A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis. PLoS ONE. 2013;8(11):e80823. doi:10.1371/journal.pone.0080823. |
Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure
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Citation:
PLoS ONE. 2013;8(11):e81854. doi:10.1371/journal.pone.0081854 Epub:
Not Epub Abstract:
Apical constriction is an essential cell behavior during neural tube closure, but its underlying mechanisms are not fully... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Chu C-W, Gerstenzang E, Ossipova O, Sokol SY. Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure. PLoS ONE. 2013;8(11):e81854. doi:10.1371/journal.pone.0081854. |
ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption
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Citation:
J Clin Invest. 2013 Nov 25. doi:pii: 69000. 10.1172/JCI69000. [Epub ahead of print] Epub:
Yes Abstract:
Identification of single-gene causes of steroid-resistant nephrotic syndrome (SRNS) has furthered the understanding of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ashraf S, Gee HY, Woerner S, Xie LX, Vega-Warner V, Lovric S, Fang H, Song X, Cattran DC, Avila-Casado C, Paterson AD, Nitschké P, Bole-Feysot C, Cochat P, Esteve-Rudd J, Haberberger B, Allen SJ, Zhou W, Airik R, Otto EA, Barua M, Al-Hamed MH, Kari JA, Evans J, Bierzynska A, Saleem MA, Böckenhauer D, Kleta R, El Desoky S, Hacihamdioglu DO, Gok F, Washburn J, Wiggins RC, Choi M, Lifton RP, Levy S, Han Z, Salviati L, Prokisch H, Williams DS, Pollak M, Clarke CF, Pei Y, Antignac C, Hildebrandt F. ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J Clin Invest. 2013 Nov 25. doi:pii: 69000. 10.1172/JCI69000. [Epub ahead of print]. |
Calcium binding is essential for plastin3 function in Smn-deficient motor neurons
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Citation:
Hum Mol Genet. 2013 Nov 23. [Epub ahead of print] Epub:
Yes Abstract:
The actin binding and bundling protein, plastin 3 (PLS3), was identified as a protective modifier of spinal muscular atrophy (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lyon AN, Pineda RH, Hao LT, Kudryashova E, Kudryashov DS, Beattie CE. Calcium binding is essential for plastin3 function in Smn-deficient motor neurons. Hum Mol Genet. 2013 Nov 23. [Epub ahead of print]. |
Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation
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Citation:
Int J Dev Neurosci. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.ijdevneu.2013.11.003 Epub:
Not Epub Abstract:
In zebrafish, cranial sensory circuits form by 4 days post-fertilization. We used a forward genetic screen to identify genes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cox JA, LaMora A, Johnson SL, Voigt MA. Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation. Int J Dev Neurosci. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.ijdevneu.2013.11.003. |
Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms
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Citation:
Neurosci Lett. 2013;[Epub ahead of print] doi:10.1016/j.neulet.2013.11.017 Epub:
Yes Abstract:
Pregabalin is widely used as an analgesic for the treatment of neuropathic pain. In the present experiments using mouse spinal... Delivery Method:
intrathecal injection Organism or Cell Type:
mouse Citation Extract: Matsuzawa R, Fujiwara T, Nemoto K, Fukushima T, Yamaguchi S, Akagawa K, Hori Y. Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms. Neurosci Lett. 2013;[Epub ahead of print] doi:10.1016/j.neulet.2013.11.017. |
Gene regulatory network for neurogenesis in a sea star embryo connects broad neural specification and localized patterning
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Citation:
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8591-6. doi: 10.1073/pnas.1220903110. Epub 2013 May 6 Epub:
Not Epub Abstract:
A great challenge in development biology is to understand how interacting networks of regulatory genes can direct the often... Delivery Method:
microinjection Organism or Cell Type:
sea star Patiria miniata Citation Extract: Yankura KA, Koechlein CS, Cryan AF, Cheatle A, Hinman VF. Gene regulatory network for neurogenesis in a sea star embryo connects broad neural specification and localized patterning. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8591-6. doi: 10.1073/pnas.1220903110. Epub 2013 May 6. |
Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish
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Citation:
Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5 Epub:
Not Epub Abstract:
Multiple signaling pathways control the specification of endothelial cells (ECs) to become arteries or veins during vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5. |
miR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos
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Citation:
Nat Commun. 2013 Nov 22;4:2829. doi: 10.1038/ncomms3829 Epub:
Not Epub Abstract:
As miR-1 and miR-206 share identical seed sequences, they are commonly speculated to target the same gene. Here, we identify an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin CY, Lee HC, Fu CY, Ding YY, Chen JS, Lee MH, Huang WJ, Tsai HJ. miR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos. Nat Commun. 2013 Nov 22;4:2829. doi: 10.1038/ncomms3829. |