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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration and angiogenesis

Authors:
Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B
Citation:
J Biol Chem. 2013 Oct 8. [Epub ahead of print]
Epub:
Yes
Abstract:
The Hippo tumor suppressor pathway plays important roles in organ size control through Lats1/2 mediated phosphorylation of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B. Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration and angiogenesis. J Biol Chem. 2013 Oct 8. [Epub ahead of print].

The role of cAMP-mediated intracellular signaling in regulating Na+ uptake in zebrafish larvae

Authors:
Kumai Y, Kwong RW, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2014 Jan 1;306(1):R51-60. doi: 10.1152/ajpregu.00317.2013. Epub 2013 Nov 20
Epub:
Not Epub
Abstract:
In the current study, the role of cAMP in stimulating Na+ uptake in larval zebrafish was investigated. Treating larvae at 4...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumai Y, Kwong RW, Perry SF . The role of cAMP-mediated intracellular signaling in regulating Na+ uptake in zebrafish larvae. Am J Physiol Regul Integr Comp Physiol. 2014 Jan 1;306(1):R51-60. doi: 10.1152/ajpregu.00317.2013. Epub 2013 Nov 20.

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling

Authors:
Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W
Citation:
Blood. 2013 Jul 25. [Epub ahead of print]
Epub:
Yes
Abstract:
Establishment and stabilization of endothelial tubes with patent lumens is vital during vertebrate development. Ras-interacting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W. Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood. 2013 Jul 25. [Epub ahead of print].

Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-γ2 (sncgb) expression in the developing notochord of zebrafish

Authors:
Lien H-W, Yang C-H, Cheng C-H, Liao Y-F, Han Y-S, Huang C-J
Citation:
Biochem Biophys Res Comm. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbrc.2013.11.042
Epub:
Yes
Abstract:
Zebrafish synuclein-γ2 (sncgb) has been reported to be expressed specifically in the notochord. However, the mechanism by which...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lien H-W, Yang C-H, Cheng C-H, Liao Y-F, Han Y-S, Huang C-J. Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-γ2 (sncgb) expression in the developing notochord of zebrafish. Biochem Biophys Res Comm. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbrc.2013.11.042.

Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration

Authors:
Ton QV, Iovine MK
Citation:
PLoS ONE. 2013;8(11):e81240. doi:10.1371/journal.pone.0081240
Epub:
Not Epub
Abstract:
Joints are essential for skeletal flexibly and form, yet the process underlying joint morphogenesis is poorly understood....
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Ton QV, Iovine MK. Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration. PLoS ONE. 2013;8(11):e81240. doi:10.1371/journal.pone.0081240.

Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice

Authors:
Shimada Y, Kuroyanagi J, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T
Citation:
Int J Obes (Lond). 2013 Nov 20. doi: 10.1038/ijo.2013.217. [Epub ahead of print]
Epub:
Yes
Abstract:
Background:The diet-induced obesity model of zebrafish (DIO-zebrafish) shares a common pathophysiological pathway with...
Delivery Method:
i.p. injection
Organism or Cell Type:
zebrafish
Citation Extract:
Shimada Y, Kuroyanagi J, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T. Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice. Int J Obes (Lond). 2013 Nov 20. doi: 10.1038/ijo.2013.217. [Epub ahead of print].

A time delay gene circuit is required for palp formation in the ascidian embryo

Authors:
Ikeda T, Matsuoka T, Satou Y
Citation:
Development. 2013;140:4703-8. doi:10.1242/dev.100339
Epub:
Not Epub
Abstract:
The ascidian larval brain and palps (a putative rudimentary placode) are specified by two transcription factor genes, ZicL and...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Ikeda T, Matsuoka T, Satou Y. A time delay gene circuit is required for palp formation in the ascidian embryo. Development. 2013;140:4703-8. doi:10.1242/dev.100339.

A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling

Authors:
Gorny A-K, Kaufmann LT, Swain RK, Steinbeisser H
Citation:
Cell Comm Signaling. 2013;11:89 doi:10.1186/1478-811X-11-89
Epub:
Not Epub
Abstract:
Background: Activation of the Wnt signalling cascade is primarily based on the interplay between Wnt ligands, their receptors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Gorny A-K, Kaufmann LT, Swain RK, Steinbeisser H. A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling. Cell Comm Signaling. 2013;11:89 doi:10.1186/1478-811X-11-89.

The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitivity, is Crucial for Vascular Development

Authors:
Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML
Citation:
Cancer Res. 2013;[Epub ahead of print]. doi:10.1158/0008-5472.CAN-13-1981
Epub:
Yes
Abstract:
ENOX1 is a highly conserved NADH oxidase that helps to regulate intracellular nicotinamide adenine dinucleotide levels in many...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML. The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitivity, is Crucial for Vascular Development. Cancer Res. 2013;[Epub ahead of print]. doi:10.1158/0008-5472.CAN-13-1981.

Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing

Authors:
Obholzer N, Swinburne IA, Schwab E, Nechiporuk AV, Nicolson T, Megason SG
Citation:
Development. 2012 Nov;139(22):4280-90. doi: 10.1242/dev.083931. Epub 2012 Oct 10
Epub:
Not Epub
Abstract:
Forward genetic screens in zebrafish have identified >9000 mutants, many of which are potential disease models. Most mutants...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Obholzer N, Swinburne IA, Schwab E, Nechiporuk AV, Nicolson T, Megason SG. Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing. Development. 2012 Nov;139(22):4280-90. doi: 10.1242/dev.083931. Epub 2012 Oct 10.

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