You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
Specific Activation of Yamanaka Factors via HSF1 Signaling in the Early Stage of Zebrafish Optic Nerve Regeneration
|
Citation:
Int J Mol Sci. 2023;24(4):3253. doi:10.3390/ijms24043253 Epub:
Not Epub Abstract:
In contrast to the case in mammals, the fish optic nerve can spontaneously regenerate and visual function can be fully restored... Delivery Method:
Vivo-Morpholino intraocular injection Organism or Cell Type:
zebrafish Citation Extract: Sugitani K, Mokuya T, Homma S, Maeda M, Konno A, Ogai K. Specific Activation of Yamanaka Factors via HSF1 Signaling in the Early Stage of Zebrafish Optic Nerve Regeneration. Int J Mol Sci. 2023;24(4):3253. doi:10.3390/ijms24043253. |
Cpeb1b-mediated cytoplasmic polyadenylation of shha mRNA modulates zebrafish definitive hematopoiesis
|
Citation:
Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2212212120. doi: 10.1073/pnas.2212212120. Epub 2023 Feb 6 Epub:
Not Epub Abstract:
During vertebrate embryogenesis, hematopoietic stem and progenitor cell (HSPC) production through endothelial-to-hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heng J, Shi B, Zhou JY, Zhang Y, Ma D, Yang YG, Liu F. Cpeb1b-mediated cytoplasmic polyadenylation of shha mRNA modulates zebrafish definitive hematopoiesis. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2212212120. doi: 10.1073/pnas.2212212120. Epub 2023 Feb 6. |
Gaucher disease protects against tuberculosis
|
Citation:
Proc Natl Acad Sci USA. 2023;120(7):e2217673120 doi:10.1073/pnas.2217673120 Epub:
Not Epub Abstract:
Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease, characterized by lysosomal accumulation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fan J, Hale VL, Lelieveld LT, Ramakrishna L. Gaucher disease protects against tuberculosis. Proc Natl Acad Sci USA. 2023;120(7):e2217673120 doi:10.1073/pnas.2217673120. |
Ubiquitylation of BBSome is required for ciliary assembly and signaling
|
Citation:
Ubiquitylation of BBSome is required for ciliary assembly and signaling. EMBO Rep. 2023 Feb 6:e55571. doi:10.15252/embr.202255571. Online ahead of print Epub:
Yes Abstract:
Bardet-Biedl syndrome (BBS) is a ciliopathy characterized by retinal degeneration, obesity, renal abnormalities, postaxial... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka fish) Citation Extract: Chiuso F, Delle Donne R, Giamundo G, Rinaldi L, Borzacchiello D, Moraca F, Intartaglia D, Iannucci R, Senatore E, Lignitto L, Garbi C, Conflitti P, Catalanotti B, Conte I, Feliciello A. Ubiquitylation of BBSome is required for ciliary assembly and signaling. Ubiquitylation of BBSome is required for ciliary assembly and signaling. EMBO Rep. 2023 Feb 6:e55571. doi:10.15252/embr.202255571. Online ahead of print. |
Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the Kidneys and Urinary Tract in Humans, Mice, and Frogs
|
Citation:
J Am Soc Nephrol. 2022 Nov 22:ASN.2022010050. doi: 10.1681/ASN.2022010050. Online ahead of print Epub:
Yes Abstract:
Background About 40 disease genes have been described to date for isolated congenital anomalies of the kidneys and urinary... Organism or Cell Type:
Xenopus Citation Extract: Klämbt V, Buerger F, Wang C, Naert T, Richter K, Nauth T, Weiss AC, Sieckmann T, Lai E, Connaughton D, Seltzsam S, Mann N, Majmundar A, Wu CH, Onuchic-Whitford A, Shril S, Schneider S, Schierbaum L, Dai R, Bekheirnia MR, Joosten M, Shlomovitz O, Vivante A, Banne E, Mane S, Lifton RP, Kirschner K, Kispert A, Rosenberger G, Fischer KD, Lienkamp S, Zegers M, Hildebrandt F . Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the Kidneys and Urinary Tract in Humans, Mice, and Frogs. J Am Soc Nephrol. 2022 Nov 22:ASN.2022010050. doi: 10.1681/ASN.2022010050. Online ahead of print. |
Confined environments induce polarized paraspeckle condensates
|
Citation:
Commun Biol 6, 145 (2023). doi:10.1038/s42003-023-04528-4 Epub:
Not Epub Abstract:
Cancer cells experience confinement as they navigate the tumour microenvironment during metastasis. Recent studies have... Delivery Method:
electroporation Organism or Cell Type:
cell culture: MDA-MB-231 human breast cancer cells Citation Extract: Todorovski V, McCluggage F, Li Y, Meid A, Spatz JP, Holle AW, Fox AH, Choi Y. Confined environments induce polarized paraspeckle condensates. Commun Biol 6, 145 (2023). doi:10.1038/s42003-023-04528-4. |
Tmem88 confines ectodermal Wnt2bb signaling in pharyngeal arch artery progenitors for balancing cell cycle progression and cell fate decision
|
Citation:
Nat Cardiovasc Res. 2023;[epub] doi:10.1038/s44161-023-00215-z Epub:
Not Epub Abstract:
Pharyngeal arch artery (PAA) progenitors undergo proliferative expansion and angioblast differentiation to build vessels... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang M, Liu J, Mao A, Ning G, Cao Y, Zhang W, Wang Q. Tmem88 confines ectodermal Wnt2bb signaling in pharyngeal arch artery progenitors for balancing cell cycle progression and cell fate decision. Nat Cardiovasc Res. 2023;[epub] doi:10.1038/s44161-023-00215-z. |
DG9-conjugated morpholino rescues phenotype in SMA mice by reaching the CNS via a subcutaneous administration
|
Citation:
JCI Insight. 2023;8(5):e160516. doi: 10.1172/jci.insight.160516. Online ahead of print Epub:
Not Epub Abstract:
Antisense oligonucleotide (AO)-mediated therapy is a promising strategy to treat several neurological diseases including spinal... Delivery Method:
peptide-linked; subcutaneous (s.c.) Organism or Cell Type:
SMA mice Citation Extract: Aslesh T, Erkut E, Ren J, Lim KRQ, Woo S, Hatlevig S, Moulton HM, Gosgnach S, Greer J, Maruyama R, Yokota T. DG9-conjugated morpholino rescues phenotype in SMA mice by reaching the CNS via a subcutaneous administration. JCI Insight. 2023;8(5):e160516. doi: 10.1172/jci.insight.160516. Online ahead of print. |
RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation
|
Citation:
Cell Rep. 2023;42(2):112407. doi:10.1016/j.celrep.2023.112047 Epub:
Not Epub Abstract:
Mammalian development is precisely controlled by cell differentiation. Identifying new regulators and investigating their... Delivery Method:
microinjection Organism or Cell Type:
mouse embryo Citation Extract: Wu D, Dean J. RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation. Cell Rep. 2023;42(2):112407. doi:10.1016/j.celrep.2023.112047. |
The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs
|
Citation:
Nat Commun. 2023 Jan 28;14(1):472. doi: 10.1038/s41467-023-36114-x Epub:
Not Epub Abstract:
Specialized chromatin-binding proteins are required for DNA-based processes during development. We recently established PWWP2A... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Herchenröther A, Gossen S, Friedrich T, Reim A, Daus N, Diegmüller F, Leers J, Sani HM, Gerstner S, Schwarz L, Stellmacher I, Szymkowiak LV, Nist A, Stiewe T, Borggrefe T, Mann M, Mackay JP, Bartkuhn M, Borchers A, Lan J, Hake SB. The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs. Nat Commun. 2023 Jan 28;14(1):472. doi: 10.1038/s41467-023-36114-x. |