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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12160 scientific papers returned from the database with the search filters currently being used below.
There are 12160 scientific papers returned from the database with the search filters currently being used below.
Utilizing Zebrafish Embryos to Reveal Disruptions in Dorsoventral Patterning
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Citation:
Curr Protoc. 2021 Jun;1(6):e179. doi: 10.1002/cpz1.179 Epub:
Not Epub Abstract:
Dorsoventral (DV) patterning is a key landmark of embryonic development that is primarily regulated by bone morphogenetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dasgupta S, Cheng V, Volz DC. Utilizing Zebrafish Embryos to Reveal Disruptions in Dorsoventral Patterning. Curr Protoc. 2021 Jun;1(6):e179. doi: 10.1002/cpz1.179. |
Perturbation of astroglial Slc38 glutamine transporters by NH4+ contributes to neurophysiologic manifestations in acute liver failure
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Citation:
FASEB J. 2021;35:e21588. doi:10.1096/fj.202001712RR Epub:
Not Epub Abstract:
Ammonia is considered the main pathogenic toxin in hepatic encephalopathy (HE). However, the molecular mechanisms involved have... Delivery Method:
Vivo-Morpholino osmotic pump to frontal cortex Organism or Cell Type:
C57Bl6 mice Citation Extract: Hamdani EH, Popek M, Frontczak-Baniewicz M, Utheim TP, Albrecht J, Zielińska M, Chaudhry FA. Perturbation of astroglial Slc38 glutamine transporters by NH4+ contributes to neurophysiologic manifestations in acute liver failure. FASEB J. 2021;35:e21588. doi:10.1096/fj.202001712RR. |
Defects of cohesin loader lead to bone dysplasia associated with transcriptional disturbance
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Citation:
J Cell Physiol. 2021;[Epub] doi:doi.org/10.1002/jcp.30491 Epub:
Not Epub Abstract:
Cohesin loader nipped-B-like protein (Nipbl) is increasingly recognized for its important role in development and cancer.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gu W, Wang, Gu R,Ouyang H, Bao B, Zheng L, Xu B. Defects of cohesin loader lead to bone dysplasia associated with transcriptional disturbance. J Cell Physiol. 2021;[Epub] doi:doi.org/10.1002/jcp.30491. |
Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code
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Citation:
Nucl Acids Res. 2021;gkab533[Epub] doi:10.1093/nar/gkab533 Epub:
Yes Abstract:
The specific recognition of splice signals at or near exon-intron junctions is not explained by their weak conservation and... Organism or Cell Type:
cell culture: HeLa Citation Extract: Saha K, Fernandez MM, Biswas T, Joseph S, Ghosh G. Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code. Nucl Acids Res. 2021;gkab533[Epub] doi:10.1093/nar/gkab533. |
The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
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Citation:
Elife. 2021 Jun 21;10:e66143. doi: 10.7554/eLife.66143 Epub:
Not Epub Abstract:
The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gentile A, Bensimon-Brito A, Priya R, Maischein HM, Piesker J, Guenther S, Gunawan F, Stainier DY. The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression. Elife. 2021 Jun 21;10:e66143. doi: 10.7554/eLife.66143. |
Genetic compensation for cilia defects in cep290/NPHP6 mutants by upregulation of cilia-associated small GTPases
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Citation:
J Cell Sci. 2021 Jun 22:jcs.258568. doi: 10.1242/jcs.258568. Online ahead of print Epub:
Yes Abstract:
Mutations in CEP290, a large multidomain coiled coil protein, are associated with multiple cilia-associated syndromes. Over 130... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cardenas-Rodriguez M, Austin-Tse C, Bergboer JGM, Molinari E, Sugano Y, Bachmann-Gagescu R, Sayer JA, Drummond IA. Genetic compensation for cilia defects in cep290/NPHP6 mutants by upregulation of cilia-associated small GTPases. J Cell Sci. 2021 Jun 22:jcs.258568. doi: 10.1242/jcs.258568. Online ahead of print. |
Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity
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Citation:
PLoS Genet. 2021;17(6):e1009641 doi:10.1371/journal.pgen.1009641 Epub:
Not Epub Abstract:
During development, the vertebrate vasculature undergoes major growth and remodeling. While the transcriptional cascade... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Quillien A, Boulet M, Ethuin S, Vandel L. Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity. PLoS Genet. 2021;17(6):e1009641 doi:10.1371/journal.pgen.1009641. |
Light-induced, spatiotemporal control of protein in the developing embryo of the sea urchin
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Citation:
Dev Biol. 2021 Jun 17:S0012-1606(21)00148-2. doi: 10.1016/j.ydbio.2021.06.006. Online ahead of print Epub:
Not Epub Abstract:
Differential protein regulation is a critical biological process that regulates cellular activity and controls cell fate... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Wavreil FDM, Poon J, Wessel GM, Yajima M. Light-induced, spatiotemporal control of protein in the developing embryo of the sea urchin. Dev Biol. 2021 Jun 17:S0012-1606(21)00148-2. doi: 10.1016/j.ydbio.2021.06.006. Online ahead of print. |
The dual-specificity protein kinase Clk3 is essential for Xenopus neural development
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Citation:
Biochem Biophys Res Commun. 2021 Jun 16;567:99-105. doi: 10.1016/j.bbrc.2021.06.005. Online ahead of print Epub:
Not Epub Abstract:
During vertebrate development, the formation of the central nervous system (CNS) is initiated by neural induction and... Organism or Cell Type:
Xenopus Citation Extract: Virgirinia RP, Nakamura M, Takebayashi-Suzuki K, Fatchiyah F, Suzuki A. The dual-specificity protein kinase Clk3 is essential for Xenopus neural development. Biochem Biophys Res Commun. 2021 Jun 16;567:99-105. doi: 10.1016/j.bbrc.2021.06.005. Online ahead of print. |
Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2
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Citation:
Stem Cell Rep. 2021;[Epub] doi:10.1016/j.stemcr.2021.05.014 Epub:
Not Epub Abstract:
Across species, hematopoietic stem and progenitor cells (HSPCs) arise during embryogenesis from a specialized arterial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Soto RA, Najia MAT, Hachimi M, Frame JM, Yette GA, da Rocha EL, Stankunas K, Daley GQ, North TE. Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2. Stem Cell Rep. 2021;[Epub] doi:10.1016/j.stemcr.2021.05.014. |