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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts

Authors:
Toosaranont J, Ruschadaariyachat S, Mujchariyakul W, Arora JK, Charoensawan V, Suktitipat B, Palmer TN, Fletcher S, Wilton SD, Mitrpant C
Citation:
Int J Mol Sci. 2022 Apr 1;23(7):3937. doi: 10.3390/ijms23073937
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is a severe, debilitating neuromuscular condition characterised by loss of motor neurons and...
Link:
https://www.mdpi.com/1422-0067/23/7/3937/htm
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: human SMA fibroblasts
Citation Extract:
Toosaranont J, Ruschadaariyachat S, Mujchariyakul W, Arora JK, Charoensawan V, Suktitipat B, Palmer TN, Fletcher S, Wilton SD, Mitrpant C. Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts. Int J Mol Sci. 2022 Apr 1;23(7):3937. doi: 10.3390/ijms23073937.

MicroRNA-22 coordinates vascular and motor neuronal pathfinding via sema4 during zebrafish development

Authors:
Sheng J, Gong J, Shi Y, Wang X, Liu D
Citation:
Open Biol. 2022 Apr;12(4):210315. doi: 10.1098/rsob.210315. Epub 2022 Apr 6
Epub:
Not Epub
Abstract:
A precise guiding signal is crucial to orchestrate directional migration and patterning of the complex vascular network and...
Link:
https://royalsocietypublishing.org/doi/10.1098/rsob.210315
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sheng J, Gong J, Shi Y, Wang X, Liu D. MicroRNA-22 coordinates vascular and motor neuronal pathfinding via sema4 during zebrafish development. Open Biol. 2022 Apr;12(4):210315. doi: 10.1098/rsob.210315. Epub 2022 Apr 6.

Cardio-respiratory and phenotypic rescue of dystrophin/utrophin-deficient mice by combination therapy

Authors:
Lin C, Han G, Jia L, Zhao Y, Song J, Ran N, Yokota T, Seow Y, Yin H
Citation:
EMBO Rep. 2022 Apr 8:e53955. doi: 10.15252/embr.202153955. Online ahead of print
Epub:
Yes
Abstract:
Duchenne muscular dystrophy (DMD) is a systemic progressive muscular disease caused by frame-disrupting mutations in the DMD...
Link:
https://www.embopress.org/doi/abs/10.15252/embr.202153955
Delivery Method:
i.v. injection
Organism or Cell Type:
dystrophin/utrophin double knock-out (DKO) mice
Citation Extract:
Lin C, Han G, Jia L, Zhao Y, Song J, Ran N, Yokota T, Seow Y, Yin H. Cardio-respiratory and phenotypic rescue of dystrophin/utrophin-deficient mice by combination therapy. EMBO Rep. 2022 Apr 8:e53955. doi: 10.15252/embr.202153955. Online ahead of print.

Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development in zebrafish

Authors:
Rice KL, Webb SE, Miller AL
Citation:
J Cell Sci. 2022 Apr 8:jcs.259564. doi: 10.1242/jcs.259564. Online ahead of print
Epub:
Yes
Abstract:
In the trunk of developing zebrafish embryos, adjacent myotome blocks transmit contractile force via myoseptal junctions (MJs...
Link:
https://journals.biologists.com/jcs/article-abstract/doi/10.1242/jcs.259564/274996/Localized-TPC1-mediated-Ca2-release-from
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rice KL, Webb SE, Miller AL. Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development in zebrafish. J Cell Sci. 2022 Apr 8:jcs.259564. doi: 10.1242/jcs.259564. Online ahead of print.

Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia

Authors:
Park K, Yoo HS, Oh CK, Lee JR, Chung HJ, Kim HN, Kim SH, Kee KM, Kim TY, Kim M, Kim BG, Ra JS, Myung K, Kim H, Han SH, Seo MD, Lee Y, Kim DW
Citation:
Cancer Med. 2022 Mar 30. doi: 10.1002/cam4.4727. Online ahead of print
Epub:
Yes
Abstract:
Cobll1 affects blast crisis (BC) progression and tyrosine kinase inhibitor (TKI) resistance in chronic myeloid leukemia (CML)....
Link:
https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.4727
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Park K, Yoo HS, Oh CK, Lee JR, Chung HJ, Kim HN, Kim SH, Kee KM, Kim TY, Kim M, Kim BG, Ra JS, Myung K, Kim H, Han SH, Seo MD, Lee Y, Kim DW. Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia. Cancer Med. 2022 Mar 30. doi: 10.1002/cam4.4727. Online ahead of print.

Negative Elongation Factor (NELF) Inhibits Premature Granulocytic Development in Zebrafish

Authors:
Huang M, Ahmed A, Wang W, Wang X, Ma C, Jiang H, Li W, Jing L
Citation:
Int J Mol Sci. 2022;23(7):3833. doi:10.3390/ijms23073833
Epub:
Not Epub
Abstract:
Gene expression is tightly regulated during hematopoiesis. Recent studies have suggested that RNA polymerase II (Pol II)...
Link:
https://www.mdpi.com/1422-0067/23/7/3833
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang M, Ahmed A, Wang W, Wang X, Ma C, Jiang H, Li W, Jing L . Negative Elongation Factor (NELF) Inhibits Premature Granulocytic Development in Zebrafish. Int J Mol Sci. 2022;23(7):3833. doi:10.3390/ijms23073833 .

Notch1 is asymmetrically distributed from the beginning of embryogenesis and controls the ventral center

Authors:
Castro Colabianchi AM, Revinski DR, Encinas PI, Baez MV, Monti RJ, Rodríguez Abinal M, Kodjabachian L, Franchini LF, López SL
Citation:
Development. 2018 Jul 17;145(14):dev159368. doi:10.1242/dev.159368
Epub:
Not Epub
Abstract:
Based on functional evidence, we have previously demonstrated that early ventral Notch1 activity restricts dorsoanterior...
Link:
https://journals.biologists.com/dev/article/145/14/dev159368/48628/Notch1-is-asymmetrically-distributed-from-the
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Castro Colabianchi AM, Revinski DR, Encinas PI, Baez MV, Monti RJ, Rodríguez Abinal M, Kodjabachian L, Franchini LF, López SL. Notch1 is asymmetrically distributed from the beginning of embryogenesis and controls the ventral center. Development. 2018 Jul 17;145(14):dev159368. doi:10.1242/dev.159368.

Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma

Authors:
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O’Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C
Citation:
Nat Commun. 2022;13(1):1677. doi:10.1038/s41467-022-29311-7
Epub:
Not Epub
Abstract:
The mesothelium lines body cavities and surrounds internal organs, widely contributing to homeostasis and regeneration....
Link:
https://www.nature.com/articles/s41467-022-29311-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O’Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C. Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma. Nat Commun. 2022;13(1):1677. doi:10.1038/s41467-022-29311-7.

Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling

Authors:
Tang D, Zheng S, Zheng Z, Liu C, Zhang J, Yan R, Wu C, Zuo N, Wu L, Xu H, Liu S, He Y
Citation:
Cell Prolif. 2022 Mar 29:e13225. doi: 10.1111/cpr.13225. Online ahead of print
Epub:
Yes
Abstract:
Objectives: To explore the role of DNA methyltransferase 1 (DNMT1) in the development of auditory system using zebrafish as...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/cpr.13225
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tang D, Zheng S, Zheng Z, Liu C, Zhang J, Yan R, Wu C, Zuo N, Wu L, Xu H, Liu S, He Y. Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling. Cell Prolif. 2022 Mar 29:e13225. doi: 10.1111/cpr.13225. Online ahead of print.

Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs

Authors:
Jiang YJ, Fann CS, Fuh JL, Chung MY, Huang HY, Chu KC, Wang YF, Hsu CL, Kao LS, Chen SP, Wang SJ
Citation:
J Headache Pain. 2022 Mar 29;23(1):39. doi: 10.1186/s10194-022-01409-9
Epub:
Not Epub
Abstract:
Background: Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contributions remain...
Link:
https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-022-01409-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang YJ, Fann CS, Fuh JL, Chung MY, Huang HY, Chu KC, Wang YF, Hsu CL, Kao LS, Chen SP, Wang SJ. Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs. J Headache Pain. 2022 Mar 29;23(1):39. doi: 10.1186/s10194-022-01409-9.

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