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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

A Missense Change in the ATG4D Gene Links Aberrant Autophagy to a Neurodegenerative Vacuolar Storage Disease

Authors:
Kyöstilä K, Syrjä P, Jagannathan V, Chandrasekar G, Jokinen TS, Seppälä EH, Becker D, Drögemüller M, Dietschi E, Drögemüller C, Lang J, Steffen F, Rohdin C, Jäderlund KH, Lappalainen AK, Hahn K, Wohlsein P, Baumgärtner W, Henke D, Oevermann A, Kere J, Lohi H, Leeb T
Citation:
PLoS Genet. 2015 Apr 15;11(4):e1005169. doi: 10.1371/journal.pgen.1005169. eCollection 2015 Apr
Epub:
Not Epub
Abstract:
Inherited neurodegenerative disorders are debilitating diseases that occur across different species. We have performed clinical...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kyöstilä K, Syrjä P, Jagannathan V, Chandrasekar G, Jokinen TS, Seppälä EH, Becker D, Drögemüller M, Dietschi E, Drögemüller C, Lang J, Steffen F, Rohdin C, Jäderlund KH, Lappalainen AK, Hahn K, Wohlsein P, Baumgärtner W, Henke D, Oevermann A, Kere J, Lohi H, Leeb T. A Missense Change in the ATG4D Gene Links Aberrant Autophagy to a Neurodegenerative Vacuolar Storage Disease. PLoS Genet. 2015 Apr 15;11(4):e1005169. doi: 10.1371/journal.pgen.1005169. eCollection 2015 Apr.

Quantitative Analysis of PMLA Nanoconjugate Components after Backbone Cleavage

Authors:
Ding H, Patil R, Portilla-Arias J, Black KL, Ljubimova JY, Eggehard Holler E
Citation:
Int J Mol Sci. 2015;16(4):8607-20. doi:10.3390/ijms16048607
Epub:
Not Epub
Abstract:
Multifunctional polymer nanoconjugates containing multiple components show great promise in cancer therapy, but in most cases...
Delivery Method:
nanoparticle
Citation Extract:
Ding H, Patil R, Portilla-Arias J, Black KL, Ljubimova JY, Eggehard Holler E. Quantitative Analysis of PMLA Nanoconjugate Components after Backbone Cleavage. Int J Mol Sci. 2015;16(4):8607-20. doi:10.3390/ijms16048607.

Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo

Authors:
Meyen D, Tarbashevich K, Banisch TU, Wittwer C, Reichman-Fried M, Maugis B, Grimaldi C, Messerschmidt EM, Raz E
Citation:
Elife. 2015 Apr 15;4. doi: 10.7554/eLife.05279
Epub:
Not Epub
Abstract:
Cell migration and polarization is controlled by signals in the environment. Migrating cells typically form filopodia that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Meyen D, Tarbashevich K, Banisch TU, Wittwer C, Reichman-Fried M, Maugis B, Grimaldi C, Messerschmidt EM, Raz E. Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo. Elife. 2015 Apr 15;4. doi: 10.7554/eLife.05279.

Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity

Authors:
Coffman JA, Wessels A, DeSchiffart C, Rydlizky K
Citation:
Dev Biol. 2014 Feb 15;386(2):302-7. doi: 10.1016/j.ydbio.2013.12.035. Epub 2013 Dec 31
Epub:
Not Epub
Abstract:
The oral-aboral axis of the sea urchin embryo is specified conditionally via a regulated feedback circuit involving the...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Coffman JA, Wessels A, DeSchiffart C, Rydlizky K. Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity. Dev Biol. 2014 Feb 15;386(2):302-7. doi: 10.1016/j.ydbio.2013.12.035. Epub 2013 Dec 31.

Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers

Authors:
Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH
Citation:
Dev Biol. 2014 Feb 15;386(2):461-72. doi: 10.1016/j.ydbio.2013.12.010. Epub 2013 Dec 17
Epub:
Not Epub
Abstract:
Neural crest development is orchestrated by a complex and still poorly understood gene regulatory network. Premigratory neural...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH. Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers. Dev Biol. 2014 Feb 15;386(2):461-72. doi: 10.1016/j.ydbio.2013.12.010. Epub 2013 Dec 17.

Nanoscale imaging of caveolin-1 membrane domains in vivo

Authors:
Gabor KA, Kim D, Kim CH, Hess ST
Citation:
PLoS One. 2015 Feb 3;10(2):e0117225. doi: 10.1371/journal.pone.0117225. eCollection 2015
Epub:
Not Epub
Abstract:
Light microscopy enables noninvasive imaging of fluorescent species in biological specimens, but resolution is generally...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gabor KA, Kim D, Kim CH, Hess ST. Nanoscale imaging of caveolin-1 membrane domains in vivo. PLoS One. 2015 Feb 3;10(2):e0117225. doi: 10.1371/journal.pone.0117225. eCollection 2015.

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

Authors:
Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E420-9. doi: 10.1073/pnas.1424576112. Epub 2015 Jan 20
Epub:
Not Epub
Abstract:
Canonical Wnt signaling plays an important role in development and disease, regulating transcription of target genes and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E420-9. doi: 10.1073/pnas.1424576112. Epub 2015 Jan 20.

The medaka dhc2 mutant reveals conserved and distinct mechanisms of Hedgehog signaling in teleosts

Authors:
Yamamoto T, Tsukahara T, Ishiguro T, Hagiwara H, Taira M, Takeda H
Citation:
BMC Dev Biol. 2015 Feb 3;15(1):9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background: Primary cilia are essential for Hedgehog (Hh) signal transduction in vertebrates. Although the core components of...
Delivery Method:
microinjection
Organism or Cell Type:
Medaka
Citation Extract:
Yamamoto T, Tsukahara T, Ishiguro T, Hagiwara H, Taira M, Takeda H. The medaka dhc2 mutant reveals conserved and distinct mechanisms of Hedgehog signaling in teleosts. BMC Dev Biol. 2015 Feb 3;15(1):9. [Epub ahead of print].

MiR-142-3p controls the specification of definitive hemangioblasts during ontogeny

Authors:
Nimmo R, Ciau-Uitz A, Ruiz-Herguido C, Soneji S, Bigas A, Patient R, Enver T
Citation:
Dev Cell. 2013 Aug 12;26(3):237-49. doi: 10.1016/j.devcel.2013.06.023. Epub 2013 Aug 1
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) emerge during embryogenesis from hemogenic endothelium, but it remains unclear how the HSC...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nimmo R, Ciau-Uitz A, Ruiz-Herguido C, Soneji S, Bigas A, Patient R, Enver T. MiR-142-3p controls the specification of definitive hemangioblasts during ontogeny. Dev Cell. 2013 Aug 12;26(3):237-49. doi: 10.1016/j.devcel.2013.06.023. Epub 2013 Aug 1.

Essential role of Apelin signaling during lymphatic development in zebrafish

Authors:
Kim JD, Kang Y, Kim J, Papangeli I, Kang H, Wu J, Park H, Nadelmann E, Rockson SG, Chun HJ, Jin SW
Citation:
Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):338-45. doi: 10.1161/ATVBAHA.113.302785. Epub 2013 Dec 5
Epub:
Not Epub
Abstract:
OBJECTIVE: Apelin and its cognate receptor Aplnr/Apj are essential for diverse biological processes. However, the function of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JD, Kang Y, Kim J, Papangeli I, Kang H, Wu J, Park H, Nadelmann E, Rockson SG, Chun HJ, Jin SW. Essential role of Apelin signaling during lymphatic development in zebrafish. Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):338-45. doi: 10.1161/ATVBAHA.113.302785. Epub 2013 Dec 5.

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