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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1

Authors:
Fior R, Maxwell AA, Ma TP, Vezzaro A, Moens CB, Amacher SL, Lewis J, Saúde L
Citation:
Development. 2012 Dec;139(24):4656-65. doi: 10.1242/dev.078923
Epub:
Not Epub
Abstract:
Somites are formed from the presomitic mesoderm (PSM) and give rise to the axial skeleton and skeletal muscles. The PSM is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fior R, Maxwell AA, Ma TP, Vezzaro A, Moens CB, Amacher SL, Lewis J, Saúde L. The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1. Development. 2012 Dec;139(24):4656-65. doi: 10.1242/dev.078923.

VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus

Authors:
Ciau-Uitz A, Pinheiro P, Kirmizitas A, Zuo J, Patient R
Citation:
Development. 2013 Jun;140(12):2632-42. doi: 10.1242/dev.090829
Epub:
Not Epub
Abstract:
The first haematopoietic stem cells share a common origin with the dorsal aorta and derive from putative adult haemangioblasts...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ciau-Uitz A, Pinheiro P, Kirmizitas A, Zuo J, Patient R. VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus. Development. 2013 Jun;140(12):2632-42. doi: 10.1242/dev.090829.

PTK7 modulates Wnt signaling activity via LRP6

Authors:
Bin-Nun N, Lichtig H, Malyarova A, Levy M, Elias S, Frank D
Citation:
Development. 2013 Dec 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Protein tyrosine kinase 7 (PTK7) is a transmembrane protein expressed in the developing Xenopus neural plate. PTK7 regulates...
Organism or Cell Type:
Xenopus
Citation Extract:
Bin-Nun N, Lichtig H, Malyarova A, Levy M, Elias S, Frank D. PTK7 modulates Wnt signaling activity via LRP6. Development. 2013 Dec 18. [Epub ahead of print].

Analysis of Pseudoxanthoma Elasticum-Causing Missense Mutants of ABCC6 In Vivo; Pharmacological Correction of the Mislocalized Proteins

Authors:
Pomozi V, Brampton C, Fülöp K, Chen LH, Apana A, Li Q, Uitto J, Le Saux O, Váradi A
Citation:
J Invest Dermatol. 2013 Nov 11. doi: 10.1038/jid.2013.482. [Epub ahead of print]
Epub:
Yes
Abstract:
Mutations in the ABCC6 gene cause soft-tissue calcification in pseudoxanthoma elasticum (PXE) and, in some patients,...
Organism or Cell Type:
Zebrafish
Citation Extract:
Pomozi V, Brampton C, Fülöp K, Chen LH, Apana A, Li Q, Uitto J, Le Saux O, Váradi A. Analysis of Pseudoxanthoma Elasticum-Causing Missense Mutants of ABCC6 In Vivo; Pharmacological Correction of the Mislocalized Proteins. J Invest Dermatol. 2013 Nov 11. doi: 10.1038/jid.2013.482. [Epub ahead of print].

Post-transcriptional regulation of wnt8a is essential to zebrafish axis development

Authors:
Wylie AD, Fleming JA, Whitener AE, Lekven AC
Citation:
Dev Biol. 2013 Dec 11. pii: S0012-1606(13)00648-9. doi: 10.1016/j.ydbio.2013.12.003. [Epub ahead of print]
Epub:
Yes
Abstract:
wnt8a is essential for normal patterning during vertebrate embryonic development, and either gain or loss-of-function gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wylie AD, Fleming JA, Whitener AE, Lekven AC. Post-transcriptional regulation of wnt8a is essential to zebrafish axis development. Dev Biol. 2013 Dec 11. pii: S0012-1606(13)00648-9. doi: 10.1016/j.ydbio.2013.12.003. [Epub ahead of print].

A unique covalent bond in basement membrane is a primordial innovation for tissue evolution

Authors:
Fidler AL, Vanacore RM, Chetyrkin SV, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza DB, Steele RE, Ivy MT; The Aspirnauts, Hudson JK, Hudson BG
Citation:
Proc Natl Acad Sci U S A. 2013;111(1):331–6. doi: 10.1073/pnas.1318499111
Epub:
Yes
Abstract:
Basement membrane, a specialized ECM that underlies polarized epithelium of eumetazoans, provides signaling cues that regulate...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Fidler AL, Vanacore RM, Chetyrkin SV, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza DB, Steele RE, Ivy MT; The Aspirnauts, Hudson JK, Hudson BG. A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Proc Natl Acad Sci U S A. 2013;111(1):331–6. doi: 10.1073/pnas.1318499111.

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish

Authors:
Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, Macrae CA
Citation:
Development. 2014 Jan;141(1):224-35. doi: 10.1242/dev.099796
Epub:
Not Epub
Abstract:
Comprehensive functional annotation of vertebrate genomes is fundamental to biological discovery. Reverse genetic screening has...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, Macrae CA. Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development. 2014 Jan;141(1):224-35. doi: 10.1242/dev.099796.

The Transcriptomics of Glucocorticoid Receptor Signaling in Developing Zebrafish

Authors:
Nesan D, Vijayan MM
Citation:
PLoS One. 2013; 8(11): e80726. doi: 10.1371/journal.pone.0080726
Epub:
Yes
Abstract:
Cortisol is the primary corticosteroid in teleosts that is released in response to stressor activation of the hypothalamus-...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Nesan D, Vijayan MM. The Transcriptomics of Glucocorticoid Receptor Signaling in Developing Zebrafish. PLoS One. 2013; 8(11): e80726. doi: 10.1371/journal.pone.0080726.

Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenes

Authors:
Nie L, Guo X, Esmailzadeh L, Zhang J, Asadi A, Collinge M, Li X, Kim J-D, Woolls M, Jin S-W, Dubrac A, Eichmann A, Simons M, Bender JR, Sadeghi1 MM
Citation:
J Clin Invest 2013. 123(12): 5082–5097. doi: 10.1172/JCI67752
Epub:
Not Epub
Abstract:
Aberrant blood vessel formation contributes to a wide variety of pathologies, and factors that regulate angiogenesis are...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Nie L, Guo X, Esmailzadeh L, Zhang J, Asadi A, Collinge M, Li X, Kim J-D, Woolls M, Jin S-W, Dubrac A, Eichmann A, Simons M, Bender JR, Sadeghi1 MM. Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenes. J Clin Invest 2013. 123(12): 5082–5097. doi: 10.1172/JCI67752.

A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling

Authors:
Gebruers E, Cordero-Maldonado ML, Gray AI, Clements C, Harvey AL, Edrada-Ebel R, de Witte PAM, Crawford AD, Esguerra CV
Citation:
PLOS ONE 2013. doi: 10.1371/journal.pone.0083293
Epub:
Yes
Abstract:
Zebrafish have recently emerged as an attractive model for the in vivo bioassay-guided isolation and characterization of...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Gebruers E, Cordero-Maldonado ML, Gray AI, Clements C, Harvey AL, Edrada-Ebel R, de Witte PAM, Crawford AD, Esguerra CV. A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling. PLOS ONE 2013. doi: 10.1371/journal.pone.0083293.

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