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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle program in zebrafish

Authors:
Yao Z, Farr III GH, Tapscott SJ, Maves L
Citation:
Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133921
Epub:
Not Epub
Abstract:
The basic helix–loop–helix factor Myod initiates skeletal muscle differentiation by directly and sequentially activating sets...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yao Z, Farr III GH, Tapscott SJ, Maves L. Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle program in zebrafish. Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133921 .

Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice

Authors:
Yin H, Saleh AF, Betts C, Camelliti P, Seow Y, Ashraf S, Arzumanov A, Hammond S, Merritt T, Gait MJ, Wood MJA
Citation:
Molecular Therapy. 2011 April 19;[Epub ahead of print] doi:10.1038/mt.2011.79
Epub:
Not Epub
Abstract:
Induced splice modulation of pre-mRNAs shows promise to correct aberrant disease transcripts and restore functional protein and...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Saleh AF, Betts C, Camelliti P, Seow Y, Ashraf S, Arzumanov A, Hammond S, Merritt T, Gait MJ, Wood MJA. Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice. Molecular Therapy. 2011 April 19;[Epub ahead of print] doi:10.1038/mt.2011.79.

Potential of oligonucleotide-mediated exon-skipping therapy for Duchenne muscular dystrophy

Authors:
Yokota T, Pistilli E, Duddy W, Nagaraju K
Citation:
Expert Opin Biol Ther. 2007 Jun;7(6):831-842
Epub:
Not Epub
Abstract:
Many of the mutations associated with Duchenne muscular dystrophy can potentially be rescued by exon-skipping therapy,...
Citation Extract:
Yokota T, Pistilli E, Duddy W, Nagaraju K. Potential of oligonucleotide-mediated exon-skipping therapy for Duchenne muscular dystrophy. Expert Opin Biol Ther. 2007 Jun;7(6):831-842.

Ptenb Mediates Gastrulation Cell Movements via Cdc42/AKT1 in Zebrafish

Authors:
Yeh CM, Liu YC, Chang CJ, Lai SL, Hsiao CD, Lee SJ
Citation:
PLoS ONE. 2011;6(4):e18702. doi:10.1371/journal.pone.0018702
Epub:
Not Epub
Abstract:
Phosphatidylinositol 3-kinase (PI3 kinase) mediates gastrulation cell migration in zebrafish via its regulation of PIP2/PIP3...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yeh CM, Liu YC, Chang CJ, Lai SL, Hsiao CD, Lee SJ. Ptenb Mediates Gastrulation Cell Movements via Cdc42/AKT1 in Zebrafish. PLoS ONE. 2011;6(4):e18702. doi:10.1371/journal.pone.0018702.

Reduced expression of vps11 causes less pigmentation in medaka, Oryzias latipes

Authors:
Yu JF, Fukamachi S, Mitani H, Hori H, Kanamori A
Citation:
Pigment Cell Res. 2006 Dec;19(6):628-34
Epub:
Not Epub
Abstract:
In this article, we describe the medaka mutant pale gray eyes (pge) that shows reduction of black, white, and silver...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Yu JF, Fukamachi S, Mitani H, Hori H, Kanamori A. Reduced expression of vps11 causes less pigmentation in medaka, Oryzias latipes. Pigment Cell Res. 2006 Dec;19(6):628-34.

Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy

Authors:
Ymlahi-Ouazzani Q, J Bronchain O, Paillard E, Ballagny C, Chesneau A, Jadaud A, Mazabraud A, Pollet N
Citation:
Neurogenetics. 2009 Jun 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by motor neuron loss and skeletal muscle atrophy....
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Ymlahi-Ouazzani Q, J Bronchain O, Paillard E, Ballagny C, Chesneau A, Jadaud A, Mazabraud A, Pollet N. Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy. Neurogenetics. 2009 Jun 11. [Epub ahead of print].

Regulation of basal body and ciliary functions by Diversin

Authors:
Yasunaga T, Itoh K, Sokol SY
Citation:
Mech Dev. 2011 Aug 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The centrosome is essential for the formation of the cilia and has been implicated in cell polarization and signaling during...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yasunaga T, Itoh K, Sokol SY. Regulation of basal body and ciliary functions by Diversin. Mech Dev. 2011 Aug 6. [Epub ahead of print].

Requirement for Zebrafish Ataxin-7 in Differentiation of Photoreceptors and Cerebellar Neurons

Authors:
Yanicostas C, Barbieri E, Hibi M, Brice A, Stevanin G, Soussi-Yanicostas N
Citation:
PLoS ONE. 2012;7(11):e50705. doi:10.1371/journal.pone.0050705
Epub:
Not Epub
Abstract:
The expansion of a polyglutamine (polyQ) tract in the N-terminal region of ataxin-7 (atxn7) is the causative event in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yanicostas C, Barbieri E, Hibi M, Brice A, Stevanin G, Soussi-Yanicostas N. Requirement for Zebrafish Ataxin-7 in Differentiation of Photoreceptors and Cerebellar Neurons. PLoS ONE. 2012;7(11):e50705. doi:10.1371/journal.pone.0050705.

Scavenger receptor A1 is required for sensing HCMV by endosomal TLR-3/-9 in monocytic THP-1 cells

Authors:
Yew KH, Carsten B, Harrison C
Citation:
Mol Immunol. 2010 Jan;47(4):883-93. doi: 10.1016/j.molimm.2009.10.009. Epub 2009 Nov 14. PMID: 19914718
Epub:
Not Epub
Abstract:
Monocytes provide initial surveillance for pathogenic glycopeptides via scavenger receptors (SRs) and for viruses via Toll-like...
Link:
https://linkinghub.elsevier.com/retrieve/pii/S0161-5890(09)00765-2
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human cytomegalovirus (HCMV)-exposed monocytes
Citation Extract:
Yew KH, Carsten B, Harrison C. Scavenger receptor A1 is required for sensing HCMV by endosomal TLR-3/-9 in monocytic THP-1 cells. Mol Immunol. 2010 Jan;47(4):883-93. doi: 10.1016/j.molimm.2009.10.009. Epub 2009 Nov 14. PMID: 19914718.

Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung

Authors:
Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH
Citation:
Dev Biol. 2013 Jan 15;373(2):267-80. doi: 10.1016/j.ydbio.2012.11.012. Epub 2012 Nov 27
Epub:
Not Epub
Abstract:
During lung development, proper epithelial cell arrangements are critical for the formation of an arborized network of tubes....
Delivery Method:
oligo bathing
Organism or Cell Type:
mouse lung organotypic culture
Citation Extract:
Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH. Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol. 2013 Jan 15;373(2):267-80. doi: 10.1016/j.ydbio.2012.11.012. Epub 2012 Nov 27.

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