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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

A peptide-morpholino oligomer conjugate targeting Staphylococcus aureus gyrA mRNA improves healing in an infected mouse cutaneous wound model

Authors:
Sawyer AJ, Wesolowski D, Gandotra N, Stojadinovic A, Izadjoo M, Altman S, Kyriakides TR
Citation:
Int J Pharmaceutics. 2013;[Epub ahead of print] doi:10.1016/j.ijpharm.2013.05.041
Epub:
Not Epub
Abstract:
Management of skin wound infections presents a serious problem in the clinic, in the community, and in both civilian and...
Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756894/
Delivery Method:
peptide-coupled
Organism or Cell Type:
Bacteria: Staphylococcus aureus in mouse
Citation Extract:
Sawyer AJ, Wesolowski D, Gandotra N, Stojadinovic A, Izadjoo M, Altman S, Kyriakides TR. A peptide-morpholino oligomer conjugate targeting Staphylococcus aureus gyrA mRNA improves healing in an infected mouse cutaneous wound model. Int J Pharmaceutics. 2013;[Epub ahead of print] doi:10.1016/j.ijpharm.2013.05.041.

A role for FoxN3 in the development of cranial cartilages and muscles in Xenopus laevis (Amphibia: Anura: Pipidae) with special emphasis on the novel rostral cartilages

Authors:
Schmidt J, Schuff M, Olsson, L
Citation:
J Anat. 2011 Feb;218(2):226-42. doi: 10.1111/j.1469-7580.2010.01315.x. Epub 2010 Nov 3.
Epub:
Not Epub
Abstract:
The origin of morphological novelties is a controversial topic in evolutionary developmental biology. The heads of anuran...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Schmidt J, Schuff M, Olsson, L. A role for FoxN3 in the development of cranial cartilages and muscles in Xenopus laevis (Amphibia: Anura: Pipidae) with special emphasis on the novel rostral cartilages. J Anat. 2011 Feb;218(2):226-42. doi: 10.1111/j.1469-7580.2010.01315.x. Epub 2010 Nov 3..

A role for Myosin 1e in cortical granule exocytosis in Xenopus oocytes

Authors:
Schietroma C, Yu HY, Wagner MC, Umbach JA, Bement WM, Gundersen CB
Citation:
J Biol Chem. 2007 Oct 5;282(40):29504-13. Epub 2007 Aug 16
Epub:
Not Epub
Abstract:
Xenopus oocytes undergo dynamic structural changes during maturation and fertilization. Among these, cortical granule...
Organism or Cell Type:
Xenopus
Citation Extract:
Schietroma C, Yu HY, Wagner MC, Umbach JA, Bement WM, Gundersen CB. A role for Myosin 1e in cortical granule exocytosis in Xenopus oocytes. J Biol Chem. 2007 Oct 5;282(40):29504-13. Epub 2007 Aug 16.

Ancient Evolutionary Origin of the Neural Crest Gene Regulatory Network

Authors:
Sauka-Spengler T, Meulemans D, Jones M, Bronner-Fraser M
Citation:
Dev Cell. 2007 Sep 4;13(3):405-420
Epub:
Not Epub
Abstract:
The vertebrate neural crest migrates from its origin, the neural plate border, to form diverse derivatives. We previously...
Organism or Cell Type:
Lamprey
Citation Extract:
Sauka-Spengler T, Meulemans D, Jones M, Bronner-Fraser M. Ancient Evolutionary Origin of the Neural Crest Gene Regulatory Network. Dev Cell. 2007 Sep 4;13(3):405-420.

Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake

Authors:
Schmajuk G, Sierakowska H, Kole R
Citation:
J Biol Chem 1999 Jul 30;274(31):21783-9
Epub:
Not Epub
Abstract:
A novel, positive read-out assay that quantifies only sequence-specific nuclear activity of antisense oligonucleotides was used...
Delivery Method:
scrape loading and free uptake
Organism or Cell Type:
cell culture: Hela and K562 cells
Citation Extract:
Schmajuk G, Sierakowska H, Kole R. Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake. J Biol Chem 1999 Jul 30;274(31):21783-9.

Axis formation and patterning in zebrafish

Authors:
Schier AF
Citation:
Curr Opin Genet Dev. 2001 Aug;11(4):393-404. Review.
Epub:
Not Epub
Abstract:
A large collection of mutations affecting zebrafish embryogenesis was described in 1996. The cloning of the affected genes has...
Delivery Method:
not applicable
Organism or Cell Type:
zebrafish
Citation Extract:
Schier AF. Axis formation and patterning in zebrafish. Curr Opin Genet Dev. 2001 Aug;11(4):393-404. Review..

Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules

Authors:
Scardigli R, Gargioli C, Tosoni D, Borello U, Sampaolesi M, Sciorati C, Cannata S, Clementi E, Brunelli S, Cossu G
Citation:
PLoS ONE. 2008 Jun 18;3(6):e2471
Epub:
Not Epub
Abstract:
BACKGROUND: sFRP-3 is a soluble antagonist of Wnts, widely expressed in developing embryos. The Wnt gene family comprises...
Organism or Cell Type:
Xenopus
Citation Extract:
Scardigli R, Gargioli C, Tosoni D, Borello U, Sampaolesi M, Sciorati C, Cannata S, Clementi E, Brunelli S, Cossu G. Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules. PLoS ONE. 2008 Jun 18;3(6):e2471.

Calcium fluxes in dorsal forerunner cells antagonize -catenin and alter left-right patterning

Authors:
Schneider I, Houston DW, Rebagliati MR, Slusarski DC
Citation:
Development. 2008 Jan;135(1):75-84. Epub 2007 Nov 28
Epub:
Not Epub
Abstract:
Establishment of the left-right axis is essential for normal organ morphogenesis and function. Ca(2+) signaling and cilia...
Organism or Cell Type:
zebrafish
Citation Extract:
Schneider I, Houston DW, Rebagliati MR, Slusarski DC. Calcium fluxes in dorsal forerunner cells antagonize -catenin and alter left-right patterning. Development. 2008 Jan;135(1):75-84. Epub 2007 Nov 28.

CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes

Authors:
Schindler K, Schultz RM
Citation:
Biol Reprod. 2009 Apr;80(4):795-803. Epub 2009 Jan 7
Epub:
Not Epub
Abstract:
Meiotic maturation in oocytes is a prolonged process that is unique because of cell cycle arrests at prophase of meiosis I (MI...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Schindler K, Schultz RM. CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes. Biol Reprod. 2009 Apr;80(4):795-803. Epub 2009 Jan 7.

Chemical and Mechanistic Toxicology Evaluation of Exon Skipping Phosphorodiamidate Morpholino Oligomers in mdx Mice

Authors:
Sazani P, Van Ness KP, Weller DL, Poage D, Nelson K, Shrewsbury SB
Citation:
Int J Toxicol. 2011 May;30(3):322-33. Epub 2011 May 3.
Epub:
Not Epub
Abstract:
AVI-4658 is a phosphorodiamidate morpholino oligomer (PMO) designed to induce skipping of dystrophin exon 51 and restore its...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx and normal
Citation Extract:
Sazani P, Van Ness KP, Weller DL, Poage D, Nelson K, Shrewsbury SB. Chemical and Mechanistic Toxicology Evaluation of Exon Skipping Phosphorodiamidate Morpholino Oligomers in mdx Mice. Int J Toxicol. 2011 May;30(3):322-33. Epub 2011 May 3..

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