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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development

Authors:
Sager JJ, Torres GE, Burton EA
Citation:
PLoS ONE. 2012;7(9):e45175. doi:10.1371/journal.pone.0045175
Epub:
Not Epub
Abstract:
DYT1 dystonia is caused by mutation of the TOR1A gene, resulting in the loss of a single glutamic acid residue near the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sager JJ, Torres GE, Burton EA. The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development. PLoS ONE. 2012;7(9):e45175. doi:10.1371/journal.pone.0045175.

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis

Authors:
Rojas-Rivera D, Armisén R, Colombo A, Martínez G, Eguiguren AL, Díaz A, Kiviluoto S, Rodríguez D, Patron M, Rizzuto R, Bultynck G, Concha ML, Sierralta J, Stutzin A, Hetz C
Citation:
Cell Death Differ. 2012 Jun;19(6):1013-26. doi: 10.1038/cdd.2011.189. Epub 2012 Jan 13.
Epub:
Not Epub
Abstract:
Transmembrane BAX inhibitor motif-containing (TMBIM)-6, also known as BAX-inhibitor 1 (BI-1), is an anti-apoptotic protein that...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rojas-Rivera D, Armisén R, Colombo A, Martínez G, Eguiguren AL, Díaz A, Kiviluoto S, Rodríguez D, Patron M, Rizzuto R, Bultynck G, Concha ML, Sierralta J, Stutzin A, Hetz C. TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis. Cell Death Differ. 2012 Jun;19(6):1013-26. doi: 10.1038/cdd.2011.189. Epub 2012 Jan 13..

TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species

Authors:
Roca FJ, Ramakrishnan L
Citation:
Cell. 2013 Apr 25;153(3):521-34. doi: 10.1016/j.cell.2013.03.022. Epub 2013 Apr 11
Epub:
Not Epub
Abstract:
Tumor Necrosis Factor (TNF) constitutes a critical host defense against tuberculosis but its excess is also implicated in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roca FJ, Ramakrishnan L. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Cell. 2013 Apr 25;153(3):521-34. doi: 10.1016/j.cell.2013.03.022. Epub 2013 Apr 11.

Transcriptional control of Rohon-Beard sensory neuron development at the neural plate border

Authors:
Rossi CC, Kaji T, Artinger KB
Citation:
Dev Dyn. 2009 Mar 19;238(4):931-943. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rohon-Beard (RB) mechanosensory neurons are among the first sensory neurons to develop, and the process by which they adopt...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rossi CC, Kaji T, Artinger KB. Transcriptional control of Rohon-Beard sensory neuron development at the neural plate border. Dev Dyn. 2009 Mar 19;238(4):931-943. [Epub ahead of print].

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Authors:
Sajish M, Zhou Q, Kishi S, Valdez DM Jr, Kapoor M, Guo M, Lee S, Kim S, Yang XL, Schimmel P
Citation:
Nat Chem Biol. 2012 Apr 15;8(6):547-54. doi: 10.1038/nchembio.937
Epub:
Not Epub
Abstract:
IFN-γ engenders strong anti-proliferative responses, in part through activation of p53. However, the long-known IFN-γ-dependent...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sajish M, Zhou Q, Kishi S, Valdez DM Jr, Kapoor M, Guo M, Lee S, Kim S, Yang XL, Schimmel P. Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. Nat Chem Biol. 2012 Apr 15;8(6):547-54. doi: 10.1038/nchembio.937.

Twisted gastrulation is a conserved extracellular BMP antagonist

Authors:
Ross JJ, Shimmi O, Vilmos P, Petryk A, Kim H, Gaudenz K, Hermanson S, Ekker SC, O'Connor MB, Marsh JL.
Citation:
Nature 2001 Mar 22;410(6827):479-483
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) signalling regulates embryonic dorsal-ventral cell fate decisions in flies, frogs and fish....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ross JJ, Shimmi O, Vilmos P, Petryk A, Kim H, Gaudenz K, Hermanson S, Ekker SC, O'Connor MB, Marsh JL.. Twisted gastrulation is a conserved extracellular BMP antagonist. Nature 2001 Mar 22;410(6827):479-483.

VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart.

Authors:
Rottbauer W, Just S, Wessels G, Trano N, Most P, Katus HA, Fishman MC.
Citation:
Genes Dev. 2005 Jul 1;19(13):1624-34.
Epub:
Not Epub
Abstract:
The strength of the heart beat can accommodate in seconds to changes in blood pressure or flow. The mechanism for such...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rottbauer W, Just S, Wessels G, Trano N, Most P, Katus HA, Fishman MC.. VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart.. Genes Dev. 2005 Jul 1;19(13):1624-34..

Xenogenesis in Teleost Fish Through Generation of Germ-Line Chimeras by Single Primordial Germ Cell Transplantation

Authors:
Saito T, Goto-Kazeto R, Arai K, Yamaha E
Citation:
Biol Reprod. 2008 Jan;78(1):159-66. Epub 2007 Sep 26
Epub:
Not Epub
Abstract:
Primordial germ cells (PGCs) are the only cells in developing embryos with the potential to transmit genetic information to the...
Organism or Cell Type:
zebrafish
Citation Extract:
Saito T, Goto-Kazeto R, Arai K, Yamaha E. Xenogenesis in Teleost Fish Through Generation of Germ-Line Chimeras by Single Primordial Germ Cell Transplantation. Biol Reprod. 2008 Jan;78(1):159-66. Epub 2007 Sep 26.

Xenopus cadherin-6 regulates growth and epithelial development of the retina

Authors:
Ruan G, Wedlich D, Koehler A
Citation:
Mech Dev. 2006 Dec;123(12):881-92. Epub 2006 Sep 1.
Epub:
Not Epub
Abstract:
Cadherins are crucial for tissue cohesion, separation of cell layers and cell migration during embryogenesis. To investigate...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ruan G, Wedlich D, Koehler A. Xenopus cadherin-6 regulates growth and epithelial development of the retina. Mech Dev. 2006 Dec;123(12):881-92. Epub 2006 Sep 1..

Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivatives

Authors:
Rogers CD, Harafuji N, Archer T, Cunningham DD, Casey ES
Citation:
Mech Dev. 2009 Jan-Feb;126(1-2):42-55. Epub 2008 Oct 17
Epub:
Not Epub
Abstract:
The SRY-related, HMG box SoxB1 transcription factors are highly homologous, evolutionarily conserved proteins that are...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rogers CD, Harafuji N, Archer T, Cunningham DD, Casey ES. Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivatives. Mech Dev. 2009 Jan-Feb;126(1-2):42-55. Epub 2008 Oct 17.

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