You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in the mouse

Authors:
Porensky PM, Mitrpant C, McGovern VL, Bevan AK, Foust KD, Kaspar BK, Wilton SD, Burghes AHM
Citation:
Hum Mol Genet. 2012 Apr 1;21(7):1625-38. Epub 2011 Dec 20. doi:10.1093/hmg/ddr600
Epub:
Not Epub
Abstract:
Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder characterized by α-motor neuron loss in the spinal cord...
Link:
http://hmg.oxfordjournals.org/content/21/7/1625.long
Delivery Method:
injection, intracerebroventricular
Organism or Cell Type:
mice, SMA model
Citation Extract:
Porensky PM, Mitrpant C, McGovern VL, Bevan AK, Foust KD, Kaspar BK, Wilton SD, Burghes AHM. A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in the mouse. Hum Mol Genet. 2012 Apr 1;21(7):1625-38. Epub 2011 Dec 20. doi:10.1093/hmg/ddr600.

A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression.

Authors:
Polli M, Amaya E
Citation:
Development. 2002 Jun;129(12):2917-27
Epub:
Not Epub
Abstract:
Xenopus laevis has been a particularly useful model organism for identifying factors involved in the induction and patterning...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Polli M, Amaya E. A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression.. Development. 2002 Jun;129(12):2917-27.

A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation

Authors:
Poitras L, Bisson N, Islam N, Moss T
Citation:
Dev Biol. 2003 Feb 15;254(2):200-14
Epub:
Not Epub
Abstract:
The MLK family of mitogen activated protein kinase kinase kinases (MAPKKK) has been shown to activate Jun N-terminal kinase/...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Poitras L, Bisson N, Islam N, Moss T. A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation. Dev Biol. 2003 Feb 15;254(2):200-14.

A two-step model for colon adenoma initiation and progression caused by APC loss

Authors:
Phelps RA, Chidester S, Dehghanizadeh S, Phelps J, Sandoval IT, Rai K, Broadbent T, Sarkar S, Burt RW, Jones DA
Citation:
Cell. 2009 May 15;137(4):623-34
Epub:
Not Epub
Abstract:
Aberrant Wnt/beta-catenin signaling following loss of the tumor suppressor adenomatous polyposis coli (APC) is thought to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Phelps RA, Chidester S, Dehghanizadeh S, Phelps J, Sandoval IT, Rai K, Broadbent T, Sarkar S, Burt RW, Jones DA. A two-step model for colon adenoma initiation and progression caused by APC loss. Cell. 2009 May 15;137(4):623-34.

Activation of Endogenous FAK via Expression of Its Amino Terminal Domain in Xenopus Embryos

Authors:
Petridou NI, Stylianou P, Christodoulou N, Rhoads D, Guan JL, Skourides PA
Citation:
PLoS One. 2012;7(8):e42577. Epub 2012 Aug 6
Epub:
Not Epub
Abstract:
Background The Focal Adhesion Kinase is a well studied tyrosine kinase involved in a wide number of cellular processes...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Petridou NI, Stylianou P, Christodoulou N, Rhoads D, Guan JL, Skourides PA. Activation of Endogenous FAK via Expression of Its Amino Terminal Domain in Xenopus Embryos. PLoS One. 2012;7(8):e42577. Epub 2012 Aug 6.

Activin redux: specification of mesodermal pattern in Xenopus by graded concentrations of endogenous activin B

Authors:
Piepenburg O, Grimmer D, Williams PH, Smith JC
Citation:
Development. 2004 Oct;131(20):4977-86.
Epub:
Not Epub
Abstract:
Mesoderm formation in the amphibian embryo occurs through an inductive interaction in which cells of the vegetal hemisphere of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Piepenburg O, Grimmer D, Williams PH, Smith JC. Activin redux: specification of mesodermal pattern in Xenopus by graded concentrations of endogenous activin B. Development. 2004 Oct;131(20):4977-86..

Activity-dependent competition regulates motor neuron axon pathfinding via PlexinA3

Authors:
Plazas PV, Nicol X, Spitzer NC
Citation:
PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1213048110
Epub:
Not Epub
Abstract:
The role of electrical activity in axon guidance has been extensively studied in vitro. To better understand its role in the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Plazas PV, Nicol X, Spitzer NC. Activity-dependent competition regulates motor neuron axon pathfinding via PlexinA3. PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1213048110 .

Amer2 is a novel negative regulator of Wnt/beta-catenin signaling involved in neuroectodermal patterning

Authors:
Pfister AS, Tanneberger K, Schambony A, Behrens J
Citation:
J Biol Chem. 2012 Jan 13;287(3):1734-41. doi: 10.1074/jbc.M111.308650. Epub 2011 Nov 28.
Epub:
Not Epub
Abstract:
Wnt/β-catenin signaling is negatively controlled by the tumor suppressor APC (adenomatous polyposis coli), which induces...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pfister AS, Tanneberger K, Schambony A, Behrens J. Amer2 is a novel negative regulator of Wnt/beta-catenin signaling involved in neuroectodermal patterning. J Biol Chem. 2012 Jan 13;287(3):1734-41. doi: 10.1074/jbc.M111.308650. Epub 2011 Nov 28..

Amer2 Protein Interacts with EB1 Protein and Adenomatous Polyposis Coli (APC) and Controls Microtubule Stability and Cell Migration

Authors:
Pfister AS, Hadjihannas MV, Roehrig W, Schambony A, Behrens J
Citation:
J Biol Chem. 2012 Oct 12;287(42):35333-40. doi: 10.1074/jbc.M112.385393. Epub 2012 Aug 16.
Epub:
Not Epub
Abstract:
EB1 is key factor in the organization of the microtubule cytoskeleton by binding to the plus-ends of microtubules and serving...
Link:
http://www.jbc.org/content/287/42/35333.long
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pfister AS, Hadjihannas MV, Roehrig W, Schambony A, Behrens J. Amer2 Protein Interacts with EB1 Protein and Adenomatous Polyposis Coli (APC) and Controls Microtubule Stability and Cell Migration. J Biol Chem. 2012 Oct 12;287(42):35333-40. doi: 10.1074/jbc.M112.385393. Epub 2012 Aug 16..

An LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the BMP System in Endothelial Cells and in Angiogenesis

Authors:
Pi X, Schmitt CE, Xie L, Portbury AL, Wu Y, Lockyer P, Dyer LA, Moser M, Bu G, Flynn EJ, Jin S-W, Patterson C
Citation:
Circ Res. 2012 Aug 17;111(5):564-74. doi: 10.1161/CIRCRESAHA.112.274597. Epub 2012 Jul 9.
Epub:
Not Epub
Abstract:
Rationale: Among the extracellular modulators of Bmp (bone morphogenetic protein) signaling, Bmper (Bmp endothelial cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pi X, Schmitt CE, Xie L, Portbury AL, Wu Y, Lockyer P, Dyer LA, Moser M, Bu G, Flynn EJ, Jin S-W, Patterson C. An LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the BMP System in Endothelial Cells and in Angiogenesis. Circ Res. 2012 Aug 17;111(5):564-74. doi: 10.1161/CIRCRESAHA.112.274597. Epub 2012 Jul 9..

Pages