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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Sox2 is required for maintenance and regeneration, but not initial development, of hair cells in the zebrafish inner ear
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Citation:
Dev Biol. 2010 Feb 15;338(2):262-9. Epub 2009 Dec 16 Epub:
Not Epub Abstract:
Sox2 has been variously implicated in maintenance of pluripotent stem cells or, alternatively, early stages of cell... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Millimaki BB, Sweet EM, Riley BB. Sox2 is required for maintenance and regeneration, but not initial development, of hair cells in the zebrafish inner ear. Dev Biol. 2010 Feb 15;338(2):262-9. Epub 2009 Dec 16. |
Spatial and temporal 'knock down' of gene expression by electroporation of double-stranded RNA and morpholinos into early postimplantation mouse embryos
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Citation:
Mech Dev. 2002 Oct;118(1-2):57 Epub:
Not Epub Abstract:
Here we report the use of double-stranded RNA (dsRNA) and morpholino technologies to specifically 'knock down' gene... Delivery Method:
Electroporation Organism or Cell Type:
Mouse embryo Citation Extract: Mellitzer G, Hallonet M, Chen L, Ang S. Spatial and temporal 'knock down' of gene expression by electroporation of double-stranded RNA and morpholinos into early postimplantation mouse embryos. Mech Dev. 2002 Oct;118(1-2):57. |
Specific and effective gene knock-down in early chick embryos using morpholinos but not pRFPRNAi vectors
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Citation:
Mech Dev. 2008 Nov-Dec;125(11-12):947-62. Epub 2008 Sep 3. Epub:
Not Epub Abstract:
In the chick embryo, two methods are now used for studying the developmental role of genes by loss-of-function approaches:... Organism or Cell Type:
chick embryo Citation Extract: Mende M, Christophorou NA, Streit A. Specific and effective gene knock-down in early chick embryos using morpholinos but not pRFPRNAi vectors. Mech Dev. 2008 Nov-Dec;125(11-12):947-62. Epub 2008 Sep 3.. |
Sphingosine 1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning
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Citation:
J Biol Chem. 2013 January 25; 288(4): 2143–2156. Epub:
Not Epub Abstract:
Sphingosine 1-phosphate (S1P) binds G-protein-coupled receptors (S1P1–5) to regulate a multitude of physiological effects,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mendelson K, Zygmunt T, Torres-Vazquez J, Evans T, Hla T. Sphingosine 1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning. J Biol Chem. 2013 January 25; 288(4): 2143–2156. . |
Src modulates contractile vascular smooth muscle function via regulation of focal adhesions
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Citation:
J Cell Physiol. 2012;227(11):3585-92. http://dx.doi.org/10.1002/jcp.24062 Epub:
Not Epub Abstract:
Src is a known regulator of focal adhesion turnover in migrating cells; but, in contrast, Src is generally assumed to play... Citation Extract: Min J, Reznichenko M, Poythress RH, Gallant CM, Vetterkind S, Li Y, Morgan KG. Src modulates contractile vascular smooth muscle function via regulation of focal adhesions. J Cell Physiol. 2012;227(11):3585-92. http://dx.doi.org/10.1002/jcp.24062. |
Sulf1 modulates BMP signaling and is required for somite morphogenesis and development of the horizontal myoseptum
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Citation:
Dev Biol. 2013 Apr 10. doi:pii: S0012-1606(13)00168-1. 10.1016/j.ydbio.2013.04.002. [Epub ahead of print] Epub:
Not Epub Abstract:
Heparan sulfate proteoglycans (HSPGs) are glycosylated extracellular or membrane-associated proteins. Their unbranched heparan... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Meyers J, Planamento J, Ebrom P, Krulewitz N, Wade E, Pownall ME. Sulf1 modulates BMP signaling and is required for somite morphogenesis and development of the horizontal myoseptum. Dev Biol. 2013 Apr 10. doi:pii: S0012-1606(13)00168-1. 10.1016/j.ydbio.2013.04.002. [Epub ahead of print]. |
Systematic discovery of nonobvious human disease models through orthologous phenotypes
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Citation:
Proc Natl Acad Sci U S A. 2010 Mar 22. [Epub ahead of print] Epub:
Not Epub Abstract:
Biologists have long used model organisms to study human diseases, particularly when the model bears a close resemblance to the... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM. Systematic discovery of nonobvious human disease models through orthologous phenotypes. Proc Natl Acad Sci U S A. 2010 Mar 22. [Epub ahead of print]. |
Targeted 'knockdown' of spliceosome function in mammalian cells
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Citation:
Nucleic Acids Res. 2005 Feb 24;33(4):e41 Epub:
Not Epub Abstract:
The existence of two sophisticated parallel splicing machineries in multicellular organisms has raised intriguing questions--... Delivery Method:
Electroporation Organism or Cell Type:
Cell Culture: EL4 Cells and Jurkat cells Citation Extract: Matter N, Konig H. Targeted 'knockdown' of spliceosome function in mammalian cells. Nucleic Acids Res. 2005 Feb 24;33(4):e41. |
Tetraspanin, CD151, is required for maintenance of trigeminal placode identity
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Citation:
J Neurochem. 2011 Apr;117(2):221-30. doi: 10.1111/j.1471-4159.2011.07190.x. Epub 2011 Feb 24 Epub:
Not Epub Abstract:
The trigeminal ganglion is the largest of the cranial ganglia and responsible for transmitting sensory information for much of... Delivery Method:
Electroporation Organism or Cell Type:
chick embryo Citation Extract: McCabe KL, Bronner M. Tetraspanin, CD151, is required for maintenance of trigeminal placode identity. J Neurochem. 2011 Apr;117(2):221-30. doi: 10.1111/j.1471-4159.2011.07190.x. Epub 2011 Feb 24. |
The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo
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Citation:
Dev Biol. 2011 Oct 1;358(1):262-76. doi: 10.1016/j.ydbio.2011.07.035. Epub 2011 Aug 4 Epub:
Not Epub Abstract:
Hedgehog (Hh) and Wnt proteins are important signals implicated in several aspects of embryonic development, including the... Organism or Cell Type:
Xenopus Citation Extract: Min TH, Kriebel M, Hou S, Pera EM. The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo. Dev Biol. 2011 Oct 1;358(1):262-76. doi: 10.1016/j.ydbio.2011.07.035. Epub 2011 Aug 4. |