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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Smyd1b is required for skeletal and cardiac muscle function in zebrafish

Authors:
Li H, Zhong Y, Wang Z, Gao J, Xu J, Chu W, Zhang J, Fang S, Du SJ
Citation:
Mol Biol Cell. 2013 Sep 25. [Epub ahead of print]
Epub:
Yes
Abstract:
Smyd1b is a member of the Smyd family, which is specifically expressed in skeletal and cardiac muscles. Smyd1b plays a key role...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li H, Zhong Y, Wang Z, Gao J, Xu J, Chu W, Zhang J, Fang S, Du SJ. Smyd1b is required for skeletal and cardiac muscle function in zebrafish. Mol Biol Cell. 2013 Sep 25. [Epub ahead of print].

Smyd1b_tv1, a Key Regulator of Sarcomere Assembly, Is Localized on the M-Line of Skeletal Muscle Fibers

Authors:
Li H, Xu J, Bian Y-H, Rotllant P, Shen T, Chu W, Zhang J, Schneider M, Du SJ
Citation:
PLoS ONE. 2011; 6(12):e28524. doi:10.1371/journal.pone.0028524
Epub:
Not Epub
Abstract:
Background Smyd1b is a member of the Smyd family that plays a key role in sarcomere assembly during myofibrillogenesis. Smyd1b...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li H, Xu J, Bian Y-H, Rotllant P, Shen T, Chu W, Zhang J, Schneider M, Du SJ. Smyd1b_tv1, a Key Regulator of Sarcomere Assembly, Is Localized on the M-Line of Skeletal Muscle Fibers. PLoS ONE. 2011; 6(12):e28524. doi:10.1371/journal.pone.0028524.

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

Authors:
Lefave CV, Squatrito M, Vorlova S, Rocco GL, Brennan CW, Holland EC, Pan YX, Cartegni L
Citation:
EMBO J. 2011 Sep 13;30(19):4084-97. doi: 10.1038/emboj.2011.259
Epub:
Not Epub
Abstract:
In tumours, aberrant splicing generates variants that contribute to multiple aspects of tumour establishment, progression and...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: cell lines and primary tumor cultures
Citation Extract:
Lefave CV, Squatrito M, Vorlova S, Rocco GL, Brennan CW, Holland EC, Pan YX, Cartegni L. Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas. EMBO J. 2011 Sep 13;30(19):4084-97. doi: 10.1038/emboj.2011.259.

Systemic Delivery of a Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy

Authors:
Leger AJ, Mosquea LM, Clayton NP, Wu IH, Weeden T, Nelson CA, Phillips L, Roberts E, Piepenhagen PA, Cheng SH, Wentworth BM
Citation:
Nucleic Acid Ther. 2013 Jan 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Expansions of CUG trinucleotide sequences in RNA transcripts provide the basis for toxic RNA gain-of-function that leads to...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mouse HSA(LR)
Citation Extract:
Leger AJ, Mosquea LM, Clayton NP, Wu IH, Weeden T, Nelson CA, Phillips L, Roberts E, Piepenhagen PA, Cheng SH, Wentworth BM. Systemic Delivery of a Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy. Nucleic Acid Ther. 2013 Jan 11. [Epub ahead of print].

TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells

Authors:
Lemjabbar-Alaoui H, Sidhu SS, Mengistab A, Gallup M, Basbaum C
Citation:
PLoS ONE. 2011;6(3):e17489. doi:10.1371/journal.pone.0017489
Epub:
Not Epub
Abstract:
Background Tobacco smoke predisposes humans and animals to develop lung tumors, but the molecular events responsible for this...
Organism or Cell Type:
cell culture: NCIH292
Citation Extract:
Lemjabbar-Alaoui H, Sidhu SS, Mengistab A, Gallup M, Basbaum C. TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells. PLoS ONE. 2011;6(3):e17489. doi:10.1371/journal.pone.0017489.

The Function of Heterodimeric AP-1 Comprised of c-Jun and c-Fos in Activin Mediated Spemann Organizer Gene Expression

Authors:
Lee SY, Yoon J, Lee HS, Hwang YS, Cha S-W, Jeong CH, Kim JI, Park JB, Lee JY, Kim SC, Park MJ, Dong Z, Kim J
Citation:
PLoS ONE. 2011;6(7):e21796. doi:10.1371/journal.pone.0021796
Epub:
Not Epub
Abstract:
Background Activator protein-1 (AP-1) is a mediator of BMP or FGF signaling during Xenopus embryogenesis. However, specific...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lee SY, Yoon J, Lee HS, Hwang YS, Cha S-W, Jeong CH, Kim JI, Park JB, Lee JY, Kim SC, Park MJ, Dong Z, Kim J. The Function of Heterodimeric AP-1 Comprised of c-Jun and c-Fos in Activin Mediated Spemann Organizer Gene Expression. PLoS ONE. 2011;6(7):e21796. doi:10.1371/journal.pone.0021796.

The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity

Authors:
Leightner AC, Hommerding CJ, Peng Y, Salisbury JL, Gainullin VG, Czarnecki PG, Sussman CR, Harris PC
Citation:
Hum Mol Genet. 2013 Feb 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Meckel syndrome (MKS) is a lethal disorder associated with renal cystic disease, encephalocele, ductal plate malformation, and...
Organism or Cell Type:
zebrafish
Citation Extract:
Leightner AC, Hommerding CJ, Peng Y, Salisbury JL, Gainullin VG, Czarnecki PG, Sussman CR, Harris PC. The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity. Hum Mol Genet. 2013 Feb 7. [Epub ahead of print].

The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction

Authors:
Li B, Kuriyama S, Moreno M, Mayor R
Citation:
Development. 2009 Oct;136(19):3267-78
Epub:
Not Epub
Abstract:
Wnt signalling is required for neural crest (NC) induction; however, the direct targets of the Wnt pathway during NC induction...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Li B, Kuriyama S, Moreno M, Mayor R. The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction. Development. 2009 Oct;136(19):3267-78.

The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis during Xenopus early development

Authors:
Li HY, Bourdelas A, Carron C, Shi DL
Citation:
Mech Dev. 2010 Mar 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
RNA-binding proteins play an important role to post-transcriptionally regulate gene expression. During early development they...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li HY, Bourdelas A, Carron C, Shi DL. The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis during Xenopus early development. Mech Dev. 2010 Mar 22. [Epub ahead of print].

The role of XTRAP-gamma in Xenopus pronephros development

Authors:
Li DH, Chan T, Satow R, Komazaki S, Hashizume K, Asashima M
Citation:
Int J Dev Biol. 2005 Jun;49(4):401-408
Epub:
Not Epub
Abstract:
We isolated and characterized the Xenopus translocon-associated protein XTRAP-gamma, one of four subunits of the translocon-...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Li DH, Chan T, Satow R, Komazaki S, Hashizume K, Asashima M. The role of XTRAP-gamma in Xenopus pronephros development. Int J Dev Biol. 2005 Jun;49(4):401-408.

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