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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm
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Citation:
eLife. 2015;10.7554/eLife.07343 Epub:
Not Epub Abstract:
Evolutionary origin of muscle is a central question when discussing mesoderm evolution. Developmental mechanisms underlying... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Andrikou C, Pai C-Y, Su Y-S, Arnone MI. Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm. eLife. 2015;10.7554/eLife.07343. |
Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations
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Citation:
Cardiovasc Res. 2015 Jul 1;107(1):143-52. doi: 10.1093/cvr/cvv148. Epub 2015 May 12 Epub:
Not Epub Abstract:
AIMS: Notch and activin receptor-like kinase 1 (ALK1) have been implicated in arterial specification, angiogenic tip/stalk cell... Organism or Cell Type:
zebrafish Citation Extract: Rochon ER, Wright DS, Schubert MM, Roman BL. Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations. Cardiovasc Res. 2015 Jul 1;107(1):143-52. doi: 10.1093/cvr/cvv148. Epub 2015 May 12. |
GABAB receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development
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Citation:
J Neurochem. 2015;[Epub ahead of print] doi:10.1111/jnc.13259 Epub:
Yes Abstract:
Metabotropic GABAB receptors are known to modulate the activity of voltage-dependent calcium channels. Previously, we have... Citation Extract: Karls A, Mynlieff M. GABAB receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development. J Neurochem. 2015;[Epub ahead of print] doi:10.1111/jnc.13259. |
CyclinD1 Down Regulation and Increased Apoptosis Are Common Features of Cohesinopathies.
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Citation:
J Cell Physiol. 2015 Jul 23. doi: 10.1002/jcp.25106. [Epub ahead of print] Epub:
Yes Abstract:
Genetic variants within components of the cohesin complex (NIPBL, SMC1A, SMC3, RAD21, PDS5, ESCO2, HDAC8) are believed to be... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fazio G, Gaston-Massuet C, Bettini LR, Graziola F, Scagliotti V, Cereda A, Ferrari L, Mazzola M, Cazzaniga G, Giordano A, Cotelli F, Bellipanni G, Biondi A, Selicorni A, Pistocchi A, Massa V. CyclinD1 Down Regulation and Increased Apoptosis Are Common Features of Cohesinopathies.. J Cell Physiol. 2015 Jul 23. doi: 10.1002/jcp.25106. [Epub ahead of print]. |
Amphipathic trans-acting phosphorothioate DNA elements mediate the delivery of uncharged nucleic acid sequences in mammalian cells
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Citation:
RSC Adv. 2015;[Epub ahead of print] soi:10.1039/C5RA12038A Epub:
Yes Abstract:
A convenient approach to the delivery of uncharged peptide nucleic acids (PNA) or phosphorodiamidate morpholino (PMO) oligomers... Delivery Method:
dTdaPS hybridization Organism or Cell Type:
cell culture: HeLa pLuc705 Citation Extract: Jain HV, Verthelyi D, Beaucage SL. Amphipathic trans-acting phosphorothioate DNA elements mediate the delivery of uncharged nucleic acid sequences in mammalian cells. RSC Adv. 2015;[Epub ahead of print] soi:10.1039/C5RA12038A . |
Common and specific downstream signaling targets controlled by Tlr2 and Tlr5 innate immune signaling in zebrafish
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Citation:
BMC Genomics. 2015;16:547 doi:10.1186/s12864-015-1740-9 Epub:
Not Epub Abstract:
Background: Although the responses to many pathogen associated molecular patterns (PAMPs) in cell cultures and extracted organs... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang S, Marín-Juez R, Meijer AH, Spaink HP. Common and specific downstream signaling targets controlled by Tlr2 and Tlr5 innate immune signaling in zebrafish. BMC Genomics. 2015;16:547 doi:10.1186/s12864-015-1740-9. |
In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy
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Citation:
Methods Mol Biol. 2015;1324:317-29. doi: 10.1007/978-1-4939-2806-4_20 Epub:
Not Epub Abstract:
Cell-penetrating peptide (CPP)-mediated delivery of phosphorodiamidate morpholino oligomers (PMO) results in efficient exon... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: skeletal H2k cells and primary cardiomyocytes from mdx mice Citation Extract: Boisguerin P, O'Donovan L, Gait MJ, Lebleu B. In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy. Methods Mol Biol. 2015;1324:317-29. doi: 10.1007/978-1-4939-2806-4_20. |
Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD
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Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv740 Epub:
Yes Abstract:
Phosphorylation of the C-terminal domain of the largest subunit of RNA polymerase II (Pol II), especially Ser2 and Ser5... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Koga M, Hayashi M, Kaida D. Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv740. |
AVI-7288 for Marburg Virus in Nonhuman Primates and Humans
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Citation:
New Engl J Med. 2015;373:339-48. doi:10.1056/NEJMoa1410345 Epub:
Not Epub Abstract:
Background: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA... Delivery Method:
infusion Organism or Cell Type:
Humans and nonhuman primates Citation Extract: Heald AE, Charleston JS, Iversen PL, Warren TK, Saoud JB, Al-Ibrahim M, Wells JW, Warfield KL, Swenson DL, Welch LS, Sazani P, Wong M, Berry D, Kaye EM, Bavari S. AVI-7288 for Marburg Virus in Nonhuman Primates and Humans. New Engl J Med. 2015;373:339-48. doi:10.1056/NEJMoa1410345. |
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment
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Citation:
Nature. 2015;523:468-71. doi:10.1038/nature14569 Epub:
Not Epub Abstract:
Haematopoietic stem and progenitor cell (HSPC) transplant is a widely used treatment for life-threatening conditions such as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 2015;523:468-71. doi:10.1038/nature14569. |