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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
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Citation:
Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201 Epub:
Yes Abstract:
Defects in primary cilium biogenesis underlie the ciliopathies, a growing group of genetic disorders. We describe a whole-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen T-MT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SA, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, UK10K Consortium, University of Washington Center for Mendelian Genomics, <database limit - authors omitted> Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA. An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201. |
Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model
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Citation:
Sci Rep. 2015;5:10351. doi:10.1038/srep10351 Epub:
Not Epub Abstract:
Retinoblastoma is a highly invasive malignant tumor that often invades the brain and metastasizes to distal organs through the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Wang J, Cao Z, Hosaka K, Jensen L, Yang H, Sun Y, Zhuang R, Liu Y, Cao Y. Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model. Sci Rep. 2015;5:10351. doi:10.1038/srep10351. |
Identification of Polycystin-2 and CFTR common targets
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Citation:
Cilia. 2015;4(Suppl 1):P4 doi:10.1186/2046-2530-4-S1-P4 Epub:
Not Epub Abstract:
Poster From Cilia 2014 Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roxo-Rosa M, Lopes SS. Identification of Polycystin-2 and CFTR common targets. Cilia. 2015;4(Suppl 1):P4 doi:10.1186/2046-2530-4-S1-P4. |
Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder
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Citation:
Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3354 Epub:
Yes Abstract:
Dominant optic atrophy (DOA) and axonal peripheral neuropathy (Charcot-Marie-Tooth type 2, or CMT2) are hereditary... Organism or Cell Type:
zebrafish Citation Extract: Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez MA, Campeanu IJ, Griffin LB, Groenewald S, Strickland AV, Tao F, Speziani F, Abreu L, Schüle R, Caporali L, La Morgia C, Maresca A, Liguori R, Lodi R, Ahmed ZM, Sund KL, Wang X, Krueger LA, Peng Y, Prada CE, Prows CA, Schorry EK, Antonellis A, Zimmerman HH, Abdul-Rahman OA, Yang Y, Downes SM, Prince J, Fontanesi F, Barrientos A, Németh AH, Carelli V, Huang T, Zuchner S, Dallman JE. Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder. Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3354. |
The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier
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Citation:
Kidney Int. 2015 Jul 8. doi: 10.1038/ki.2015.197. [Epub ahead of print] Epub:
Yes Abstract:
Podocyte dysfunction impairs the size selectivity of the glomerular filter, leading to proteinuria, hypoalbuminuria, and edema... Organism or Cell Type:
zebrafish Citation Extract: Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S, Cohen CD, Neuhauss SC, Loffing J. The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney Int. 2015 Jul 8. doi: 10.1038/ki.2015.197. [Epub ahead of print]. |
Genetic compensation induced by deleterious mutations but not gene knockdowns
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Citation:
Nature. 2015 Aug 13;524(7564):230-3. doi: 10.1038/nature14580. Epub 2015 Jul 13 Epub:
Yes Abstract:
Cells sense their environment and adapt to it by fine-tuning their transcriptome. Wired into this network of gene expression... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rossi A, Kontarakis Z, Gerri C, Nolte H, Hölper S, Krüger M, Stainier DYR. Genetic compensation induced by deleterious mutations but not gene knockdowns. Nature. 2015 Aug 13;524(7564):230-3. doi: 10.1038/nature14580. Epub 2015 Jul 13. |
Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish
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Citation:
PLoS ONE. 2015;10(7):e0131908. doi:10.1371/journal.pone.0131908 Epub:
Not Epub Abstract:
Genetic screens are a powerful tool to discover genes that are important in immune cell development and function. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Seiler C, Gebhart N, Zhang Y, Shinton SA, Li Y-s, Ross NL, Liu X, Li Q, Bilbee AN, Varshney GK, LaFave MC, Burgess SM, Balciuniene J, Balciunas D, Hardy RR, Kappes DJ, Wiest DL, Rhodes J. Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish. PLoS ONE. 2015;10(7):e0131908. doi:10.1371/journal.pone.0131908. |
Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio
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Citation:
Invert Neurosci. 2015;15:4 doi:10.1007/s10158-015-0180-1 Epub:
Not Epub Abstract:
Oligodendrocytes produce multi-lamellar myelin membranes that surround axons in the central nervous system (CNS). Preservation... Organism or Cell Type:
zebrafish Citation Extract: Morris JF, Chomyk A, Song P, Parker N, Deckard S, Trapp BD, Pimplikar SW, Dutta R. Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio. Invert Neurosci. 2015;15:4 doi:10.1007/s10158-015-0180-1. |
Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32
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Citation:
J Biol Chem. 2015 May 12. pii: jbc.M115.650747. [Epub ahead of print] Epub:
Not Epub Abstract:
Tryptophan was substituted for residues in all four transmembrane domains of connexin32. Function was assayed using dual cell... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM. Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32. J Biol Chem. 2015 May 12. pii: jbc.M115.650747. [Epub ahead of print]. |
Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of R-Smads to Ensure TGFβ-mediated Germ Layer Induction in Xenopus Embryos
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Citation:
J Biol Chem. 2015 May 26. pii: jbc.M115.655605. [Epub ahead of print] Epub:
Yes Abstract:
Germ layer induction is one of the earliest events shortly after fertilization that initiates body formation of vertebrate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Sun G, Hu Z, Min Z, Yan X, Guan Z, Su H, Fu Y, Ma X, Chen YG, Zhang MQ, Tao Q, Wu W. Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of R-Smads to Ensure TGFβ-mediated Germ Layer Induction in Xenopus Embryos. J Biol Chem. 2015 May 26. pii: jbc.M115.655605. [Epub ahead of print]. |