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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells

Authors:
Breznau EB, Semack AC, Higashi T, Miller AL
Citation:
Mol Biol Cell. 2015;26:13 2439-2455. doi:10.1091/mbc.E14-11-1553
Epub:
Not Epub
Abstract:
Localized activation of Rho GTPases is essential for multiple cellular functions, including cytokinesis and formation and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Breznau EB, Semack AC, Higashi T, Miller AL. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells. Mol Biol Cell. 2015;26:13 2439-2455. doi:10.1091/mbc.E14-11-1553.

The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish

Authors:
Willems B, Tao S, Yu T, Huysseune A, Witten PE, Winkler C
Citation:
PLoS ONE. 2015;10(6):e0131768. doi:10.1371/journal.pone.0131768
Epub:
Not Epub
Abstract:
During vertebrate neurulation, cranial neural crest cells (CNCCs) undergo epithelial to mesenchymal transition (EMT),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willems B, Tao S, Yu T, Huysseune A, Witten PE, Winkler C. The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish. PLoS ONE. 2015;10(6):e0131768. doi:10.1371/journal.pone.0131768.

A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation

Authors:
Gil Jang D, Jung Sim H, Kyung Song E, Medina-Ruiz S, Kon Seo J, Joo Park T
Citation:
Dev Biol. 2015 Jun 24. pii: S0012-1606(15)30012-9. doi: 10.1016/j.ydbio.2015.06.005. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The sh3bgr (SH3 domain binding glutamate-rich) gene encodes a small protein containing a thioredoxin-like fold, SH3 binding...
Organism or Cell Type:
Xenopus
Citation Extract:
Gil Jang D, Jung Sim H, Kyung Song E, Medina-Ruiz S, Kon Seo J, Joo Park T. A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation. Dev Biol. 2015 Jun 24. pii: S0012-1606(15)30012-9. doi: 10.1016/j.ydbio.2015.06.005. [Epub ahead of print].

FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP

Authors:
Yu Y, Reed R
Citation:
PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1506282112
Epub:
Not Epub
Abstract:
The protein fused-in-sarcoma (FUS) is mutated to cause the neurodegenerative disease amyotrophic lateral sclerosis, but its...
Organism or Cell Type:
in vitro transcription-splicing system
Citation Extract:
Yu Y, Reed R. FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP. PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1506282112.

Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling

Authors:
Toruń A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M
Citation:
PLoS One. 2015 Jun 25;10(6):e0130818. doi: 10.1371/journal.pone.0130818. eCollection 2015
Epub:
Not Epub
Abstract:
Many adaptor proteins involved in endocytic cargo transport exhibit additional functions in other cellular processes which may...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toruń A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M. Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS One. 2015 Jun 25;10(6):e0130818. doi: 10.1371/journal.pone.0130818. eCollection 2015.

Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish

Authors:
Liu Y, Chen X, Qin B, Zhao K, Zhao Q, Staley JP, Zhao C
Citation:
J Ophthalmol. 2015;(2015):816329 doi:10.1155/2015/816329
Epub:
Not Epub
Abstract:
Purpose. The small nuclear ribonucleoprotein 200 kDa (SNRNP200) gene is a fundamental component for precursor message RNA (pre-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Chen X, Qin B, Zhao K, Zhao Q, Staley JP, Zhao C. Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish. J Ophthalmol. 2015;(2015):816329 doi:10.1155/2015/816329.

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells

Authors:
Wu L, Wary KK, Revskoy S, Gao X, Tsang K, Komarova YA, Rehman J, Malik AB
Citation:
Stem Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.stemcr.2015.05.016
Epub:
Yes
Abstract:
Understanding epigenetic mechanisms regulating embryonic stem cell (ESC) differentiation to endothelial cells may lead to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu L, Wary KK, Revskoy S, Gao X, Tsang K, Komarova YA, Rehman J, Malik AB. Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells. Stem Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.stemcr.2015.05.016.

Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging

Authors:
Fujisawa K, Terai S, Matsumoto T, Takami T, Yamamoto N, Nishina H, Furutani-Seiki M, Sakaida I
Citation:
PLoS ONE. 2015;10(6): e0129950. doi:10.1371/journal.pone.0129950
Epub:
Not Epub
Abstract:
Maid is a helix-loop-helix protein that is involved in cell proliferation. In order to further elucidate its physiological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fujisawa K, Terai S, Matsumoto T, Takami T, Yamamoto N, Nishina H, Furutani-Seiki M, Sakaida I. Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging. PLoS ONE. 2015;10(6): e0129950. doi:10.1371/journal.pone.0129950.

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism

Authors:
Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M
Citation:
Sci Rep. 2015;5:11603. doi:10.1038/srep11603
Epub:
Not Epub
Abstract:
. . Insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) signalling is required for normal embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis and Xenopus tropicalis
Citation Extract:
Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M. Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism. Sci Rep. 2015;5:11603. doi:10.1038/srep11603.

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy

Authors:
Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJA
Citation:
Sci Rep. 2015;5:11632. doi:10.1038/srep11632
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by absence of the integral structural protein, dystrophin, which renders muscle...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice, mdx
Citation Extract:
Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJA. Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy. Sci Rep. 2015;5:11632. doi:10.1038/srep11632.

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