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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse
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Citation:
Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping gene therapy for Duchenne muscular... Delivery Method:
injection Organism or Cell Type:
mice, mdx Citation Extract: Zhang A, Uaesoontrachoon K, Shaughnessy C, Das JR, Rayavarapu S, Brown KJ, Ray PE, Nagaraju K, van den Anker JN, Hoffman EP, Hathout Y. The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse. Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008. |
miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth
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Citation:
Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print] Epub:
Yes Abstract:
Connectivity and function of neuronal circuitry require the correct specification and growth of axons and dendrites. Here we... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Carrella S, D'Agostino Y, Barbato S, Huber-Reggi SP, Salierno FG, Manfredi A, Neuhauss SC, Banfi S, Conte I. miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth. Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print]. |
Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology
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Citation:
Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2015.05.005 Epub:
Yes Abstract:
The diverse morphologies of animal tissues are underlain by different configurations of adherent cells and extracellular matrix... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jülich D, Cobb G, Melo AM, McMillen P, Lawton AK, Mochrie SGJ, Rhoades E, Holley SA. Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology. Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2015.05.005. |
The chromatin remodeler chd5 is necessary for proper head development during embryogenesis of Danio rerio
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Citation:
Biochim Biophys Acta. 2015 Jun 16. pii: S1874-9399(15)00129-7. doi: 10.1016/j.bbagrm.2015.06.006. [Epub ahead of print] Epub:
Yes Abstract:
The chromatin remodeler CHD5 plays a critical role in tumor suppression and neurogenesis in mammals. CHD5 contributes to gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bishop B, Ho KK, Tyler K, Smith A, Bonilla S, Leung YF, Ogas J. The chromatin remodeler chd5 is necessary for proper head development during embryogenesis of Danio rerio. Biochim Biophys Acta. 2015 Jun 16. pii: S1874-9399(15)00129-7. doi: 10.1016/j.bbagrm.2015.06.006. [Epub ahead of print]. |
Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus
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Citation:
EBioMedicine. 2014 Nov 13;1(2-3):107-15. doi: 10.1016/j.ebiom.2014.11.009. eCollection 2014 Dec Epub:
Not Epub Abstract:
Mutations in Inverted Formin 2 (INF2), a diaphanous formin family protein that regulates actin cytoskeleton dynamics, cause... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun H, Al-Romaih KI, MacRae CA, Pollak MR. Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus. EBioMedicine. 2014 Nov 13;1(2-3):107-15. doi: 10.1016/j.ebiom.2014.11.009. eCollection 2014 Dec. |
E2F8 as a Novel Therapeutic Target for Lung Cancer
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Citation:
J Natl Cancer Inst. 2015 Jun 18;107(9). pii: djv151. doi: 10.1093/jnci/djv151. Print 2015 Sep Epub:
Not Epub Abstract:
BACKGROUND: The E2F members have been divided into transcription activators (E2F1-E2F3) and repressors (E2F4-E2F8). E2F8 with... Organism or Cell Type:
cell culture: human lung cancer (LC) cells, xenograft models Vivo-Morpholino Citation Extract: Park SA, Platt J, Lee JW, López-Giráldez F, Herbst RS, Koo JS. E2F8 as a Novel Therapeutic Target for Lung Cancer. J Natl Cancer Inst. 2015 Jun 18;107(9). pii: djv151. doi: 10.1093/jnci/djv151. Print 2015 Sep. |
The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development
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Citation:
Hum Mol Genet. 2015 Jun 18. pii: ddv213. [Epub ahead of print] Epub:
Yes Abstract:
DDX11 was recently identified as a cause of Warsaw breakage syndrome (WABS). However, the functional mechanism of DDX11 and the... Organism or Cell Type:
zebrafish Citation Extract: Sun X, Chen H, Deng Z, Hu B, Luo H, Zeng X, Han L, Cai G, Ma L. The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development. Hum Mol Genet. 2015 Jun 18. pii: ddv213. [Epub ahead of print]. |
A Phase I/IIa Clinical Trial in Duchenne Muscular Dystrophy Using Systemically Delivered Morpholino Antisense Oligomer to Skip Exon 53 (SKIP-NMD)
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Citation:
Human Gene Therapy Clinical Development. June 2015, 26(2): 92-95. doi:10.1089/humc.2015.2528 Epub:
Not Epub Organism or Cell Type:
cell culture, tox models, humans Citation Extract: No Authors Listed. A Phase I/IIa Clinical Trial in Duchenne Muscular Dystrophy Using Systemically Delivered Morpholino Antisense Oligomer to Skip Exon 53 (SKIP-NMD). Human Gene Therapy Clinical Development. June 2015, 26(2): 92-95. doi:10.1089/humc.2015.2528. |
Biological Roles of Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1), HSD11B2, and Glucocorticoid Receptor (NR3C1) in Sheep Conceptus Elongation
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Citation:
Biol Reprod. 2015 Jun 17. pii: biolreprod.115.130757. [Epub ahead of print] Epub:
Yes Abstract:
In sheep, the elongating conceptus synthesizes and secretes interferon tau (IFNT), as well as prostaglandins (PGs) and cortisol... Delivery Method:
Endo-Porter Organism or Cell Type:
Ovis aries (sheep) Citation Extract: Brooks K, Burns G, Spencer TE. Biological Roles of Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1), HSD11B2, and Glucocorticoid Receptor (NR3C1) in Sheep Conceptus Elongation. Biol Reprod. 2015 Jun 17. pii: biolreprod.115.130757. [Epub ahead of print]. |
Spatio-Temporal Differences in Dystrophin Dynamics at mRNA and Protein Levels Revealed by a Novel FlipTrap Line
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Citation:
PLoS ONE. 2015;10(6):e0128944. doi:10.1371/journal.pone.0128944 Epub:
Not Epub Abstract:
Dystrophin (Dmd) is a structural protein that links the extracellular matrix to actin filaments in muscle fibers and is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ruf-Zamojski F, Trivedi V, Fraser SE, Trinh LA. Spatio-Temporal Differences in Dystrophin Dynamics at mRNA and Protein Levels Revealed by a Novel FlipTrap Line. PLoS ONE. 2015;10(6):e0128944. doi:10.1371/journal.pone.0128944. |