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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis
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Citation:
eLife. 2015;4:e06489. doi:10.7554/eLife.06489 Epub:
Not Epub Abstract:
Despite the critical role of endothelial Wnt/β-catenin signaling during central nervous system (CNS) vascularization, how... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vanhollebeke B, Stone OA, Bostaille N, Cho C, Zhou Y, Maquet E, Gauquier A, Cabochette P, Fukuhara S, Mochizuki N, Nathans J, Stainier DYR. Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis. eLife. 2015;4:e06489. doi:10.7554/eLife.06489. |
A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase
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Citation:
PLoS Genet. 2015 Jun 8;11(6):e1005286. doi: 10.1371/journal.pgen.1005286. eCollection 2015 Jun Epub:
Not Epub Abstract:
The TERT-CLPTM1L region of chromosome 5p15.33 is a multi-cancer susceptibility locus that encodes the reverse transcriptase... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293T Citation Extract: Killedar A, Stutz MD, Sobinoff AP, Tomlinson CG, Bryan TM, Beesley J, Chenevix-Trench G, Reddel RR, Pickett HA. A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase. PLoS Genet. 2015 Jun 8;11(6):e1005286. doi: 10.1371/journal.pgen.1005286. eCollection 2015 Jun. |
Hepassocin is required for hepatic outgrowth during zebrafish hepatogenesis
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Citation:
Biochem Biophys Res Commun. 2015 Jun 3. pii: S0006-291X(15)30045-0. doi: 10.1016/j.bbrc.2015.05.121. [Epub ahead of print] Epub:
Yes Abstract:
Background & aims: Hepassocin (HPS) is a hepatotrophic growth factor that specifically stimulates hepatocyte proliferation... Organism or Cell Type:
zebrafish Citation Extract: Gao M, Yan H, Yin RH, Wang Q, Zhan YQ, Yu M, Ge CH, Li CY, Wang XH, Ge ZQ, Yang XM. Hepassocin is required for hepatic outgrowth during zebrafish hepatogenesis. Biochem Biophys Res Commun. 2015 Jun 3. pii: S0006-291X(15)30045-0. doi: 10.1016/j.bbrc.2015.05.121. [Epub ahead of print]. |
Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies
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Citation:
Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.05.010 Epub:
Yes Abstract:
Desminopathies belong to a family of muscle disorders called myofibrillar myopathies that are caused by Desmin mutations and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ramspacher C, Steed E, Boselli F, Ferreira R, Faggianelli N, Roth S, Spiegelhalter C, Messaddeq N, Trinh L, Liebling M, Chacko N, Tessadori F, Bakkers J, Laporte J, Hnia K, Vermot J. Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies. Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.05.010. |
TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport
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Citation:
Nat Commun. 2015;[Epub ahead of print] doi:10.1038/ncomms8074 Epub:
Yes Abstract:
The analysis of individuals with ciliary chondrodysplasias can shed light on sensitive mechanisms controlling ciliogenesis and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schmidts M, Hou Y, Cortes CR, Mans DA, Huber C, Boldt K, Patel M, van Reeuwijk J, Plaza J-M, van Beersum SEC, Yap ZM, Letteboer SJF, Taylor SP, Herridge W, Johnson CA, Scambler PJ, Ueffing M, Kayserili H, Krakow D, King SM, Beales PL, Al-Gazali L, Wicking C, Cormier-Daire V, Roepman R, Mitchison HM, Witman GB, UK10K. TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport. Nat Commun. 2015;[Epub ahead of print] doi:10.1038/ncomms8074. |
Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides
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Citation:
Nano Lett. 2015;[Epub ahead of print] doi:10.1021/acs.nanolett.5b00490 Epub:
Yes Abstract:
Antisense oligonucleotides (ASOs) have the potential of revolutionizing medicine due to their ability to manipulate gene... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture, mice Citation Extract: Ahmed K, Aoki Y, Koo T, McClorey G, Benner L, Coenen-Stass A, O'Donovan L, Lehto T, Garciaguerra A, Nordin JZ, Saleh AF, Behlke MA, Morris , Goyenvalle A, Dugovic B, Leumann CJ, Gordon S, Gait MJ, El-Andaloussi S, Wood MJA. Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides. Nano Lett. 2015;[Epub ahead of print] doi:10.1021/acs.nanolett.5b00490. |
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells
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Citation:
Cell Rep. 2015 doi:10.1016/j.celrep.2015.05.018 Epub:
Not Epub Abstract:
Sprouting blood vessels are led byfilopodia-studded endothelial tip cells that respond to angiogenic signals. Mosaic lineage... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fantin A, Lampropoulou A, Gestri G, Raimondi C, Senatore V, Zachary I, Ruhrberg C. NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells. Cell Rep. 2015 doi:10.1016/j.celrep.2015.05.018. |
The Chromatin Remodeling Protein Bptf Promotes Posterior Neuroectodermal Fate by Enhancing Smad2-Activated wnt8a Expression
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Citation:
J Neurosci. 2015; 35(22):8493-506. doi:10.1523/JNEUROSCI.0377-15.2015 Epub:
Not Epub Abstract:
During vertebrate embryogenesis, the neuroectoderm is induced from dorsal ectoderm and then partitioned into anterior and... Organism or Cell Type:
zebrafish Citation Extract: Ma Y, Liu X, Liu1 Z, Wei S, Shang H, Xue Y, Cao Y, Meng A, Wang Q. The Chromatin Remodeling Protein Bptf Promotes Posterior Neuroectodermal Fate by Enhancing Smad2-Activated wnt8a Expression. J Neurosci. 2015; 35(22):8493-506. doi:10.1523/JNEUROSCI.0377-15.2015. |
A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect
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Citation:
Sci Rep. 2015 Jun 3;5:10673. doi: 10.1038/srep10673 Epub:
Not Epub Abstract:
mibnn2002, found from an allele screen, showed early segmentation defect and severe cell death phenotypes, which are different... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hsu CH, Lin JS, Po Lai K, Li JW, Chan TF, You MS, Tse WK, Jiang YJ. A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect. Sci Rep. 2015 Jun 3;5:10673. doi: 10.1038/srep10673. |
The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation
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Citation:
Haematologica. 2015 Jun;100(6):720-9. doi: 10.3324/haematol.2014.114488. Epub 2015 Mar 20 Epub:
Not Epub Abstract:
Feline leukemia virus subgroup C receptor 1 (Flvcr1) encodes two heme exporters: FLVCR1a, which localizes to the plasma... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mercurio S, Petrillo S, Chiabrando D, Bassi ZI, Gays D, Camporeale A, Vacaru A, Miniscalco B, Valperga G, Silengo L, Altruda F, Baron MH, Santoro MM, Tolosano E. The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation. Haematologica. 2015 Jun;100(6):720-9. doi: 10.3324/haematol.2014.114488. Epub 2015 Mar 20. |