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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development

Authors:
Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC
Citation:
Dev Biol. 2015 May 21. pii: S0012-1606(15)00280-8. doi: 10.1016/j.ydbio.2015.05.011. [Epub ahead of print]
Epub:
Yes
Abstract:
Angiogenesis relies on specialized endothelial tip cells to extend toward guidance cues in order to direct growing blood...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615002808
Organism or Cell Type:
zebrafish
Citation Extract:
Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC. Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development. Dev Biol. 2015 May 21. pii: S0012-1606(15)00280-8. doi: 10.1016/j.ydbio.2015.05.011. [Epub ahead of print].

Paraxis is required for somite morphogenesis and differentiation in Xenopus laevis

Authors:
Sánchez RS, Sánchez SS
Citation:
Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24294. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: In most vertebrates the segmentation of the paraxial mesoderm involves the formation of metameric units called...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24294/abstract
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sánchez RS, Sánchez SS. Paraxis is required for somite morphogenesis and differentiation in Xenopus laevis. Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24294. [Epub ahead of print].

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish

Authors:
Shimada Y, Kuninaga S, Ariyoshi M, Zhang B, Shiina Y, Takahashi Y, Umemoto N, Nishimura Y, Enari H, Tanaka T
Citation:
Nutrition & Metabolism. 2015;12(1). doi:10.1186/s12986-015-0012-7
Epub:
Not Epub
Abstract:
Background Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the...
Link:
http://www.nutritionandmetabolism.com/content/12/1/17/abstract
Delivery Method:
injection (i.p.) with Lipofectamine 2000
Organism or Cell Type:
zebrafish
Citation Extract:
Shimada Y, Kuninaga S, Ariyoshi M, Zhang B, Shiina Y, Takahashi Y, Umemoto N, Nishimura Y, Enari H, Tanaka T. E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish. Nutrition & Metabolism. 2015;12(1). doi:10.1186/s12986-015-0012-7.

Lymphatic vessels arise from specialized angioblasts within a venous niche

Authors:
Nicenboim J, Malkinson G, Lupo T, Asaf L, Sela Y, Mayseless O, Gibbs-Bar L, Senderovich N, Hashimshony T, Shin M, Jerafi-Vider A, Avraham-Davidi I, Krupalnik V, Hofi R, Almog G, Astin JW, Golani O, Ben-Dor S, Crosier PS, Herzog W, Lawson ND, Hanna JH, Yanai I, Yaniv K
Citation:
Nature. 2015 May 20. doi: 10.1038/nature14425. [Epub ahead of print]
Epub:
Yes
Abstract:
How cells acquire their fate is a fundamental question in developmental and regenerative biology. Multipotent progenitors...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14425.html
Organism or Cell Type:
zebrafish
Citation Extract:
Nicenboim J, Malkinson G, Lupo T, Asaf L, Sela Y, Mayseless O, Gibbs-Bar L, Senderovich N, Hashimshony T, Shin M, Jerafi-Vider A, Avraham-Davidi I, Krupalnik V, Hofi R, Almog G, Astin JW, Golani O, Ben-Dor S, Crosier PS, Herzog W, Lawson ND, Hanna JH, Yanai I, Yaniv K. Lymphatic vessels arise from specialized angioblasts within a venous niche. Nature. 2015 May 20. doi: 10.1038/nature14425. [Epub ahead of print].

Transcriptional regulator PRDM12 is essential for human pain perception

Authors:
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J
Citation:
Nat Genet. 2015 May 25. doi: 10.1038/ng.3308. [Epub ahead of print]
Epub:
Yes
Abstract:
Pain perception has evolved as a warning mechanism to alert organisms to tissue damage and dangerous environments. In humans,...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3308.html
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J. Transcriptional regulator PRDM12 is essential for human pain perception. Nat Genet. 2015 May 25. doi: 10.1038/ng.3308. [Epub ahead of print].

Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1

Authors:
Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, Vigorito E, FitzGerald GA, O'Neill LA
Citation:
Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7231-6. doi: 10.1073/pnas.1501327112. Epub 2015 May 20.
Epub:
Yes
Abstract:
The response to an innate immune challenge is conditioned by the time of day, but the molecular basis for this remains unclear...
Link:
http://www.pnas.org/content/early/2015/05/20/1501327112.abstract
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: bone-marrow-derived macrophage (BMDM)
Citation Extract:
Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, Vigorito E, FitzGerald GA, O'Neill LA. Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7231-6. doi: 10.1073/pnas.1501327112. Epub 2015 May 20..

Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain

Authors:
Sato T, Sato F, Kamezaki A, Sakaguchi K, Tanigome R, Kawakami K, Sehara-Fujisawa A
Citation:
PLoS One. 2015 May 22;10(5):e0127360. doi: 10.1371/journal.pone.0127360. eCollection 2015
Epub:
Not Epub
Abstract:
Post-mitotic neurons are generated from neural progenitor cells (NPCs) at the expense of their proliferation. Molecular and...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127360
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sato T, Sato F, Kamezaki A, Sakaguchi K, Tanigome R, Kawakami K, Sehara-Fujisawa A. Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain. PLoS One. 2015 May 22;10(5):e0127360. doi: 10.1371/journal.pone.0127360. eCollection 2015.

Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1

Authors:
Fuse Y, Nakajima H, Nakajima-Takagi Y, Nakajima O, Kobayashi M
Citation:
Genes Cells. 2015 May 18. doi: 10.1111/gtc.12249. [Epub ahead of print]
Epub:
Yes
Abstract:
The induction of the gene encoding heme oxygenase 1 (Hmox1, HO-1) by Nrf2 is unique compared with other Nrf2 targets. We...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/gtc.12249/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fuse Y, Nakajima H, Nakajima-Takagi Y, Nakajima O, Kobayashi M. Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1. Genes Cells. 2015 May 18. doi: 10.1111/gtc.12249. [Epub ahead of print].

Ribonuclease like 5 regulates zebrafish yolk extension by suppressing a p53-dependent DNA damage response pathway

Authors:
Zhai Y, Zhao X, Sheng J, Gao X, Ou Z, Xu Z
Citation:
Int J Biochem Cell Biol. 2015 May 14. pii: S1357-2725(15)00125-9. doi: 10.1016/j.biocel.2015.05.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Ribonuclease like 5 (Rnasel5) is a novel member of the zebrafish ribonuclease A family and its expression is increased during...
Link:
http://www.sciencedirect.com/science/article/pii/S1357272515001259
Organism or Cell Type:
zebrafish
Citation Extract:
Zhai Y, Zhao X, Sheng J, Gao X, Ou Z, Xu Z. Ribonuclease like 5 regulates zebrafish yolk extension by suppressing a p53-dependent DNA damage response pathway. Int J Biochem Cell Biol. 2015 May 14. pii: S1357-2725(15)00125-9. doi: 10.1016/j.biocel.2015.05.004. [Epub ahead of print].

Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome

Authors:
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG
Citation:
Nat Genet. 2015 May 25. doi: 10.1038/ng.3311. [Epub ahead of print]
Epub:
Yes
Abstract:
Docosahexanoic acid (DHA) is the most abundant omega-3 fatty acid in brain, and, although it is considered essential,...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3311.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome. Nat Genet. 2015 May 25. doi: 10.1038/ng.3311. [Epub ahead of print].

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