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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in Xenopus
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Citation:
PLoS Genet. 2015;11(3):e1005018. doi:10.1371/journal.pgen.1005018 Epub:
Not Epub Abstract:
The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Griffin JN, Sondalle SB, del Viso F, Baserga SJ, Khokha MK. The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in Xenopus. PLoS Genet. 2015;11(3):e1005018. doi:10.1371/journal.pgen.1005018. |
Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin
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Citation:
Development. 2015;142:1137-45. doi:10.1242/dev.116632 Epub:
Not Epub Abstract:
Otoliths are biomineralised structures important for balance and hearing in fish. Their counterparts in the mammalian inner ear... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Stooke-Vaughan GA, Obholzer ND, Baxendale S, Megason SG, Whitfield TT. Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin. Development. 2015;142:1137-45. doi:10.1242/dev.116632. |
Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9
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Citation:
Development. 2015 Feb 27. pii: dev.117424. [Epub ahead of print] Epub:
Yes Abstract:
Loss of neurons that express the neuropeptide hypocretin (Hcrt) has been implicated in narcolepsy, a debilitating disorder... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development. 2015 Feb 27. pii: dev.117424. [Epub ahead of print]. |
The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation
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Citation:
Development. 2015;142:1146-1158. doi:10.1242/dev.113886 Epub:
Yes Abstract:
Germ layer formation and primary axis development rely on Fibroblast growth factors (FGFs). In Xenopus, the secreted serine... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Acosta H, Iliev D, Grahn THM, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM. The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation. Development. 2015;142:1146-1158. doi:10.1242/dev.113886. |
Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy
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Citation:
EMBO Mol Med. 2015;[Epub ahead of print] doi:10.15252/emmm.201505047 Epub:
Not Epub Abstract:
Frameshift mutations in the TTN gene encoding titin are a major cause for inherited forms of dilated cardiomyopathy (DCM), a... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Gramlich M, Pane LS, Zhou Q, Chen Z, Murgia M, Schötterl S, Goedel A, Metzger K, Brade T, Parrotta E, Schaller M, Gerull B, Thierfelder L, Aartsma-Rus A, Labeit S, Atherton JJ, McGaughran J, Harvey RP, Sinnecker D, Mann M, Laugwitz K-L, Gawaz MP, Moretti A. Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy. EMBO Mol Med. 2015;[Epub ahead of print] doi:10.15252/emmm.201505047. |
Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo
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Citation:
Development. 2015;142:1050-1061. doi:10.1242/dev.119180 Epub:
Not Epub Abstract:
The adult blood system is established by hematopoietic stem cells (HSCs), which arise during development from an endothelial-to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni C-W, Stachura DL, Del Cid N, Espín-Palazón R, Lawson ND, Dorsky R, Clements WK, Traver D. Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo. Development. 2015;142:1050-1061. doi:10.1242/dev.119180 . |
MASH1/Ascl1a Leads to GAP43 Expression and Axon Regeneration in the Adult CNS
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Citation:
PLoS ONE. 2015;10(3):e0118918. doi:10.1371/journal.pone.0118918 Epub:
Not Epub Abstract:
Unlike CNS neurons in adult mammals, neurons in fish and embryonic mammals can regenerate their axons after injury. These... Delivery Method:
gelfoam at lesion Organism or Cell Type:
zebrafish Citation Extract: Williams RR, Venkatesh I, Pearse DD, Udvadia AJ, Bunge MB. MASH1/Ascl1a Leads to GAP43 Expression and Axon Regeneration in the Adult CNS. PLoS ONE. 2015;10(3):e0118918. doi:10.1371/journal.pone.0118918. |
BDNF-TrkB Axis Regulates Migration of the Lateral Line Primordium and Modulates the Maintenance of Mechanoreceptor Progenitors
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Citation:
PLoS ONE. 2015;10(3):e0119711. doi:10.1371/journal.pone.0119711 Epub:
Not Epub Abstract:
.BDNF and its specialized receptor TrkB are expressed in the developing lateral line system of zebrafish, but their role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gasanov EV, Rafieva LM, Korzh VP. BDNF-TrkB Axis Regulates Migration of the Lateral Line Primordium and Modulates the Maintenance of Mechanoreceptor Progenitors. PLoS ONE. 2015;10(3):e0119711. doi:10.1371/journal.pone.0119711. |
Claudin-10 is required for relay of left-right patterning cues from Hensen's node to the lateral plate mesoderm
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Citation:
Dev Biol. 2015 Mar 2. pii: S0012-1606(15)00089-5. doi: 10.1016/j.ydbio.2015.02.019. [Epub ahead of print] Epub:
Yes Abstract:
Species-specific symmetry-breaking events at the left-right organizer (LRO) drive an evolutionarily-conserved cascade of gene... Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Collins MM, Amanda IB, Simard A, Gregory M, Cyr DG, Ryan AK. Claudin-10 is required for relay of left-right patterning cues from Hensen's node to the lateral plate mesoderm. Dev Biol. 2015 Mar 2. pii: S0012-1606(15)00089-5. doi: 10.1016/j.ydbio.2015.02.019. [Epub ahead of print]. |
Cell Adhesion Mediated by VCAM–ITGa9 Interactions Enables Lymphatic Development
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Citation:
Arterioscler Thromb Vasc Biol. 2015;[Epub ahead of print] doi:10.1161/ATVBAHA.114.304997 Epub:
Yes Abstract:
Objective—Adhesive ligand–receptor interactions play key roles in blood vessel angiogenesis but remain poorly characterized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang Y, Enis D, Zheng H, Chia S, Yang Y, Chen M, Dhillon V, Papayannapoulou T, Kahn ML. Cell Adhesion Mediated by VCAM–ITGa9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol. 2015;[Epub ahead of print] doi:10.1161/ATVBAHA.114.304997. |