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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Long-chain Acyl-CoA synthetase 4A regulates Smad activity and dorsoventral patterning in the zebrafish embryo

Authors:
Miyares RL, Stein C, Renisch B, Anderson JL, Hammerschmidt M, Farber SA
Citation:
Dev Cell. 2013 Dec 23;27(6):635-47. doi: 10.1016/j.devcel.2013.11.011. Epub 2013 Dec 12
Epub:
Not Epub
Abstract:
Long-chain polyunsaturated fatty acids (LC-PUFA) and their metabolites are critical players in cell biology and embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyares RL, Stein C, Renisch B, Anderson JL, Hammerschmidt M, Farber SA. Long-chain Acyl-CoA synthetase 4A regulates Smad activity and dorsoventral patterning in the zebrafish embryo. Dev Cell. 2013 Dec 23;27(6):635-47. doi: 10.1016/j.devcel.2013.11.011. Epub 2013 Dec 12.

Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1)

Authors:
Regadas I, Matos MR, Monteiro FA, Gómez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C
Citation:
J Biol Chem. 2013 Dec 20;288(51):36285-301. doi: 10.1074/jbc.M113.491993. Epub 2013 Nov 8
Epub:
Not Epub
Abstract:
The homeodomain transcription factor Prrxl1/DRG11 has emerged as a crucial molecule in the establishment of the pain circuitry...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Regadas I, Matos MR, Monteiro FA, Gómez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C. Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1). J Biol Chem. 2013 Dec 20;288(51):36285-301. doi: 10.1074/jbc.M113.491993. Epub 2013 Nov 8.

IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling

Authors:
Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H
Citation:
J Biol Chem. 2013 Dec 20;288(51):36351-60. doi: 10.1074/jbc.M113.520528. Epub 2013 Nov 6
Epub:
Not Epub
Abstract:
In the canonical Wnt signaling pathway, the translocation of β-catenin is important for the activation of target genes in the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H. IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling. J Biol Chem. 2013 Dec 20;288(51):36351-60. doi: 10.1074/jbc.M113.520528. Epub 2013 Nov 6.

A mutation in cnot8, component of the Ccr4-not complex regulating transcript stability, affects expression levels of developmental regulators and reveals a role of Fgf3 in development of caudal hypothalamic dopaminergic neurons

Authors:
Koch P, Löhr HB, Driever W
Citation:
PLoS One. 2014 Dec 5;9(12):e113829. doi: 10.1371/journal.pone.0113829. eCollection 2014
Epub:
Not Epub
Abstract:
While regulation of the activity of developmental control genes at the transcriptional level as well as by specific miRNA-based...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koch P, Löhr HB, Driever W. A mutation in cnot8, component of the Ccr4-not complex regulating transcript stability, affects expression levels of developmental regulators and reveals a role of Fgf3 in development of caudal hypothalamic dopaminergic neurons. PLoS One. 2014 Dec 5;9(12):e113829. doi: 10.1371/journal.pone.0113829. eCollection 2014.

Characterization of zebrafish Abcc4 as an efflux transporter of organochlorine pesticides

Authors:
Lu X, Long Y, Lin L, Sun R, Zhong S, Cui Z
Citation:
PLoS One. 2014 Dec 5;9(12):e111664. doi: 10.1371/journal.pone.0111664. eCollection 2014
Epub:
Not Epub
Abstract:
DDT and lindane are highly toxic organochlorine pesticides and posing adverse effects on the environment and public health due...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu X, Long Y, Lin L, Sun R, Zhong S, Cui Z. Characterization of zebrafish Abcc4 as an efflux transporter of organochlorine pesticides. PLoS One. 2014 Dec 5;9(12):e111664. doi: 10.1371/journal.pone.0111664. eCollection 2014.

Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins

Authors:
Hirose K, Shiomi T, Hozumi S, Kikuchi Y
Citation:
BMC Dev Biol. 2014 Dec 6;14(1):42. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background: The mechanistic target of rapamycin complex1 (mTORC1) signaling pathway has been implicated in functions of...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Hirose K, Shiomi T, Hozumi S, Kikuchi Y. Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins. BMC Dev Biol. 2014 Dec 6;14(1):42. [Epub ahead of print].

Analysis of skeletal muscle defects in larval zebrafish by birefringence and touch-evoke escape response assays

Authors:
Smith LL, Beggs AH, Gupta VA
Citation:
J Vis Exp. 2013 Dec 13;(82):e50925. doi: 10.3791/50925
Epub:
Not Epub
Abstract:
Zebrafish (Danio rerio) have become a particularly effective tool for modeling human diseases affecting skeletal muscle,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smith LL, Beggs AH, Gupta VA. Analysis of skeletal muscle defects in larval zebrafish by birefringence and touch-evoke escape response assays. J Vis Exp. 2013 Dec 13;(82):e50925. doi: 10.3791/50925.

Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL

Authors:
Burgoyne T, O'Connor MN, Seabra MC, Cutler DF, Futter CE
Citation:
J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.164400
Epub:
Yes
Abstract:
Analysis of melanosome biogenesis in the retinal pigment epithelium (RPE) is challenging because it occurs predominantly in a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burgoyne T, O'Connor MN, Seabra MC, Cutler DF, Futter CE. Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL. J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.164400.

Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac neural crest versus heart mesoderm

Authors:
Nie S, Bronner ME
Citation:
Cardiovasc Res. 2015;[Epub ahead of print] doi:/10.1093/cvr/cvv043
Epub:
Yes
Abstract:
Aims: Ets1 is an important transcription factor that is expressed in both the cardiac neural crest and heart mesoderm of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nie S, Bronner ME. Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac neural crest versus heart mesoderm. Cardiovasc Res. 2015;[Epub ahead of print] doi:/10.1093/cvr/cvv043.

An anti-inflammatory NOD-like receptor is required for microglia development

Authors:
Shiau CE, Monk KR, Joo W, Talbot WS
Citation:
Cell Rep. 2013 Dec 12;5(5):1342-52. doi: 10.1016/j.celrep.2013.11.004. Epub 2013 Dec 5
Epub:
Not Epub
Abstract:
Microglia are phagocytic cells that form the basis of the brain's immune system. They derive from primitive macrophages...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shiau CE, Monk KR, Joo W, Talbot WS. An anti-inflammatory NOD-like receptor is required for microglia development. Cell Rep. 2013 Dec 12;5(5):1342-52. doi: 10.1016/j.celrep.2013.11.004. Epub 2013 Dec 5.

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