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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

cPKC regulates interphase nuclear size during Xenopus development

Authors:
Edens LJ, Levy DL
Citation:
J Cell Biol. 2014;206(4):473 doi:10.1083/jcb.201406004
Epub:
Not Epub
Abstract:
Dramatic changes in cell and nuclear size occur during development and differentiation, and aberrant nuclear size is associated...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Edens LJ, Levy DL. cPKC regulates interphase nuclear size during Xenopus development. J Cell Biol. 2014;206(4):473 doi:10.1083/jcb.201406004 .

To Discover, Develop and Deliver a Right Drug: A Showcase for Antisense Technology

Authors:
Li YF
Citation:
J Drug Disc Dev Del. 2014;1(1):3
Epub:
Not Epub
Abstract:
No abstract available
Citation Extract:
Li YF. To Discover, Develop and Deliver a Right Drug: A Showcase for Antisense Technology. J Drug Disc Dev Del. 2014;1(1):3.

Systematic discovery of novel ciliary genes through functional genomics in the zebrafish

Authors:
Choksi SP, Babu D, Lau D, Yu X, Roy S
Citation:
Development. 2014;141:3410-3419. doi:10.1242/dev.108209
Epub:
Not Epub
Abstract:
Cilia are microtubule-based hair-like organelles that play many important roles in development and physiology, and are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choksi SP, Babu D, Lau D, Yu X, Roy S. Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development. 2014;141:3410-3419. doi:10.1242/dev.108209 .

Knockdown of αIIb by RNA degradation by delivering deoxyoligonucleotides piggybacked with control vivo-morpholinos into zebrafish thrombocytes

Authors:
Sundaramoorthi H, Khandekar G, Kim S, Jagadeeswaran P
Citation:
Blood Cell Molec Dis. 2014;[Epub ahead of print] doi:10.1016/j.bcmd.2014.07.016
Epub:
Not Epub
Abstract:
Morpholino and vivo-morpholino gene knockdown methods have been used to study thrombocyte function in zebrafish. However, a...
Delivery Method:
Vivo-Morpholino piggyback
Organism or Cell Type:
zebrafish
Citation Extract:
Sundaramoorthi H, Khandekar G, Kim S, Jagadeeswaran P. Knockdown of αIIb by RNA degradation by delivering deoxyoligonucleotides piggybacked with control vivo-morpholinos into zebrafish thrombocytes. Blood Cell Molec Dis. 2014;[Epub ahead of print] doi:10.1016/j.bcmd.2014.07.016.

Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development

Authors:
Karmodiya K, Anamika K, Muley V, Pradhan SJ, Bhide Y, Galande S
Citation:
Sci Rep. 2014 Aug 15;4:6076. doi: 10.1038/srep06076
Epub:
Not Epub
Abstract:
In this study, we have investigated genome-wide occurrence of Histone Acetyltransferases (HATs) in genomes of Mus musculus and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Karmodiya K, Anamika K, Muley V, Pradhan SJ, Bhide Y, Galande S. Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development. Sci Rep. 2014 Aug 15;4:6076. doi: 10.1038/srep06076.

Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts

Authors:
Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O
Citation:
Dev Biol. 2014 Aug 12. pii: S0012-1606(14)00377-7. doi: 10.1016/j.ydbio.2014.07.025. [Epub ahead of print]
Epub:
Yes
Abstract:
The kidney is a homeostatic organ required for waste excretion and reabsorption of water, salts and other macromolecules. To...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O. Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts. Dev Biol. 2014 Aug 12. pii: S0012-1606(14)00377-7. doi: 10.1016/j.ydbio.2014.07.025. [Epub ahead of print].

Upregulation of Functional Kv11.1 Isoform Expression by Inhibition of Intronic Polyadenylation with Antisense Morpholino Oligonucleotides

Authors:
Gong Q, Stump MR, Zhou Z
Citation:
J Mol Cell Cardiol. 2014;76:26-32. doi:10.1016/j.yjmcc.2014.08.007
Epub:
Yes
Abstract:
The KCNH2 gene encodes the Kv11.1 potassium channel that conducts the rapidly activating delayed rectifier current in the heart...
Citation Extract:
Gong Q, Stump MR, Zhou Z. Upregulation of Functional Kv11.1 Isoform Expression by Inhibition of Intronic Polyadenylation with Antisense Morpholino Oligonucleotides. J Mol Cell Cardiol. 2014;76:26-32. doi:10.1016/j.yjmcc.2014.08.007.

A Self-Organizing miR-132/Ctbp2 Circuit Regulates Bimodal Notch Signals and Glial Progenitor Fate Choice during Spinal Cord Maturation

Authors:
Salta E, Lau P, Frigerio CS, Coolen M, Bally-Cuif L, De Strooperemail B
Citation:
Dev Cell. 2014;[Epub ahead of print] doi:10.1016/j.devcel.2014.07.006
Epub:
Yes
Abstract:
Radial glial progenitors play pivotal roles in the development and patterning of the spinal cord, and their fate is controlled...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Salta E, Lau P, Frigerio CS, Coolen M, Bally-Cuif L, De Strooperemail B. A Self-Organizing miR-132/Ctbp2 Circuit Regulates Bimodal Notch Signals and Glial Progenitor Fate Choice during Spinal Cord Maturation. Dev Cell. 2014;[Epub ahead of print] doi:10.1016/j.devcel.2014.07.006.

Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance

Authors:
Payne F, Colnaghi R, Rocha N, Seth A, Harris J, Carpenter G, Bottomley WE, Wheeler E, Wong S, Saudek V, Savage D, O'Rahilly S, Carel JC, Barroso I, O'Driscoll M, Semple R
Citation:
J Clin Invest. 2014 Aug 8. pii: 73264. doi: 10.1172/JCI73264. [Epub ahead of print]
Epub:
Yes
Abstract:
Structural maintenance of chromosomes (SMC) complexes are essential for maintaining chromatin structure and regulating gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Payne F, Colnaghi R, Rocha N, Seth A, Harris J, Carpenter G, Bottomley WE, Wheeler E, Wong S, Saudek V, Savage D, O'Rahilly S, Carel JC, Barroso I, O'Driscoll M, Semple R. Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance. J Clin Invest. 2014 Aug 8. pii: 73264. doi: 10.1172/JCI73264. [Epub ahead of print].

Overlapping and Opposing Functions of GRK2 and GRK5 during Heart Development

Authors:
Philipp M, Berger IM, Just S, Caron MG
Citation:
J Biol Chem. 2014 Aug 7. pii: jbc.M114.551952. [Epub ahead of print]
Epub:
Yes
Abstract:
G protein-coupled receptor kinases 2 (GRK2) and 5 (GRK5) are fundamental regulators of cardiac performance in adults, but are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Philipp M, Berger IM, Just S, Caron MG. Overlapping and Opposing Functions of GRK2 and GRK5 during Heart Development. J Biol Chem. 2014 Aug 7. pii: jbc.M114.551952. [Epub ahead of print].

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