You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology
|
Citation:
Development. 2014 Aug;141(16):3103-4. doi: 10.1242/dev.112003 Epub:
Not Epub Abstract:
Morpholino oligomers have been used widely and for many years in the zebrafish community to transiently knock down the function... Citation Extract: Schulte-Merker S, Stainier DY. Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology. Development. 2014 Aug;141(16):3103-4. doi: 10.1242/dev.112003. |
Critical roles of DNase1l3l in lens nuclear degeneration in zebrafish
|
Citation:
Biochimie. 2014;[Epub ahead of print] doi:10.1016/j.biochi.2014.07.025 Epub:
Yes Abstract:
The vertebrate lens undergoes organelle and nuclear degradation during lens development, allowing the lens to become... Organism or Cell Type:
zebrafish Citation Extract: Iida A, Tabata Y, Baba Y, Fujii T, Watanabe S. Critical roles of DNase1l3l in lens nuclear degeneration in zebrafish. Biochimie. 2014;[Epub ahead of print] doi:10.1016/j.biochi.2014.07.025. |
Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injury
|
Citation:
J Biol Chem. 2014;[Epub ahead of print] doi:10.1074/jbc.M114.602383 Epub:
Yes Abstract:
IL-6/Stat3 is associated with the regulation of transcription of key cellular regulatory genes [microRNAs (miRNAs)] during... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Francis H, McDaniel K, Han Y, Liu X, Kennedy L, Yang F, McCarra J, Zhou T, Glaser S, Venter J, Huang L, Levine P, Lai J-M, Liu C-G, Alpini G, Meng F. Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injury. J Biol Chem. 2014;[Epub ahead of print] doi:10.1074/jbc.M114.602383 . |
An Otx/Nodal Regulatory Signature for Posterior Neural Development in Ascidians
|
Citation:
PLoS Genet. 2014;10(8):e1004548. doi:10.1371/journal.pgen.1004548 Epub:
Not Epub Abstract:
In chordates, neural induction is the first step of a complex developmental process through which ectodermal cells acquire a... Link:
Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis Citation Extract: Roure A, Lemaire P, Darras S. An Otx/Nodal Regulatory Signature for Posterior Neural Development in Ascidians. PLoS Genet. 2014;10(8):e1004548. doi:10.1371/journal.pgen.1004548. |
CRISPR-Mediated Genomic Deletion of Sox2 in the Axolotl Shows a Requirement in Spinal Cord Neural Stem Cell Amplification during Tail Regeneration
|
Citation:
Stem Cell Rep. 2014 Sep 9;3(3):444-59. doi: 10.1016/j.stemcr.2014.06.018. Epub 2014 Aug 7. Epub:
Not Epub Abstract:
The salamander is the only tetrapod that functionally regenerates all cell types of the limb and spinal cord (SC) and thus... Delivery Method:
microinjection Organism or Cell Type:
Ambystoma mexicanum (axolotl) Citation Extract: Fei J-F, Schuez M, Tazaki A, Taniguchi Y, Roensch K, Tanaka EM. CRISPR-Mediated Genomic Deletion of Sox2 in the Axolotl Shows a Requirement in Spinal Cord Neural Stem Cell Amplification during Tail Regeneration. Stem Cell Rep. 2014 Sep 9;3(3):444-59. doi: 10.1016/j.stemcr.2014.06.018. Epub 2014 Aug 7.. |
A Heroin Addiction Severity-Associated Intronic Single Nucleotide Polymorphism Modulates Alternative Pre-mRNA Splicing of the μ Opioid Receptor Gene OPRM1 via hnRNPH Interactions
|
Citation:
J Neurosci. 2014;34(33):11048-66. doi:10.1523/JNEUROSCI.3986-13.2014 Epub:
Not Epub Abstract:
Single nucleotide polymorphisms (SNPs) in the OPRM1 gene have been associated with vulnerability to opioid dependence. The... Organism or Cell Type:
cell culture Citation Extract: Xu J, Lu Z, Xu M, Pan L, Deng Y, Xie X, Liu H, Ding S, Hurd YL, Pasternak GW, Klein RJ, Cartegni L, Zhou W, Pan Y-X. A Heroin Addiction Severity-Associated Intronic Single Nucleotide Polymorphism Modulates Alternative Pre-mRNA Splicing of the μ Opioid Receptor Gene OPRM1 via hnRNPH Interactions. J Neurosci. 2014;34(33):11048-66. doi:10.1523/JNEUROSCI.3986-13.2014. |
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model
|
Citation:
J Clin Invest. 2014 Aug 8. pii: 76175. doi: 10.1172/JCI76175. [Epub ahead of print] Epub:
Yes Abstract:
X-linked agammaglobulinemia (XLA) is an inherited immunodeficiency that results from mutations within the gene encoding Bruton... Delivery Method:
Peptide-linked or bare oligo Organism or Cell Type:
mice, cell culture: U2OS reporter cell line Citation Extract: Bestas B, Moreno PM, Blomberg KE, Mohammad DK, Saleh AF, Sutlu T, Nordin JZ, Guterstam P, Gustafsson MO, Kharazi S, Piątosa B, Roberts TC, Behlke MA, Wood MJ, Gait MJ, Lundin KE, El Andaloussi S, Månsson R, Berglöf A, Wengel J, Smith CI. Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model. J Clin Invest. 2014 Aug 8. pii: 76175. doi: 10.1172/JCI76175. [Epub ahead of print]. |
Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1
|
Citation:
Nature. 2014;[Epub ahead of print] doi:10.1038/nature13678 Epub:
Yes Abstract:
Haematopoietic stem cells (HSCs) are self-renewing stem cells capable of replenishing all blood lineages. In all vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nguyen PD, Hollway GE, Sonntag C, Miles LB, Hall TE, Berger S, Fernandez KJ, Gurevich DB, Cole NJ, Alaei S, Ramialison M, Sutherland RL, Polo JM, Lieschke GJ, Currie PD. Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1. Nature. 2014;[Epub ahead of print] doi:10.1038/nature13678. |
L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way
|
Citation:
Brit J Haematol. 2014;[Epub ahead of print] doi:10.1111/bjh.13069 Epub:
Yes Abstract:
Haploinsufficiency of ribosomal proteins (RPs) and upregulation of the tumour suppressor TP53 have been shown to be the common... Organism or Cell Type:
zebrafish Citation Extract: Narla A, Payne EM, Abayasekara N, Hurst SN, Raiser DM, Look AT, Berliner N, Ebert BL Khanna-Gupta A. L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way. Brit J Haematol. 2014;[Epub ahead of print] doi:10.1111/bjh.13069. |
Deadenylase depletion protects inherited mRNAs in primordial germ cells
|
Citation:
Development. 2014;141:3134-42. doi:10.1242/dev.110395 Epub:
Not Epub Abstract:
A crucial event in animal development is the specification of primordial germ cells (PGCs), which become the stem cells that... Delivery Method:
microinjection Organism or Cell Type:
Sea urchin Strongylocentrotus purpuratus Citation Extract: Swartz SZ, Reich AM, Oulhen N, Raz T, Milos PM, Campanale JP, Hamdoun A, Wessel GM. Deadenylase depletion protects inherited mRNAs in primordial germ cells. Development. 2014;141:3134-42. doi:10.1242/dev.110395. |