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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Phosphorodiamidate Morpholino Oligomers (PMOs) suppress mutant huntingtin expression and attenuate neurotoxicity
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Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu349 Epub:
Yes Abstract:
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the huntingtin... Organism or Cell Type:
mice, cell culture: patient fibroblasts Citation Extract: Sun X, Marque LO, Cordner Z, Pruitt JL, Bhat M, Li P, Kannan G, Ladenheim EE, Moran TH, Margolis RL, Rudnicki DD. Phosphorodiamidate Morpholino Oligomers (PMOs) suppress mutant huntingtin expression and attenuate neurotoxicity. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu349 . |
Reversing paclitaxel resistance in ovarian cancer cells via inhibition of the ABCB1 expressing side population
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Citation:
Tumour Biol. 2014 Jul 4. [Epub ahead of print] Epub:
Yes Abstract:
The majority of deaths in ovarian cancer are caused by recurrent metastatic disease which is usually multidrug resistant. This... Organism or Cell Type:
cell culture: ovarian cancer cell line Citation Extract: Eyre R, Harvey I, Stemke-Hale K, Lennard TW, Tyson-Capper A, Meeson AP. Reversing paclitaxel resistance in ovarian cancer cells via inhibition of the ABCB1 expressing side population. Tumour Biol. 2014 Jul 4. [Epub ahead of print]. |
Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos
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Citation:
Circ Res. 2014 Jan 3;114(1):56-66. doi: 10.1161/CIRCRESAHA.114.302452. Epub 2013 Oct 11 Epub:
Not Epub Abstract:
RATIONALE: The emergence of lymphatic endothelial cells (LECs) seems to be highly regulated during development. Although... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dunworth WP, Cardona-Costa J, Bozkulak EC, Kim JD, Meadows S, Fischer JC, Wang Y, Cleaver O, Qyang Y, Ober EA, Jin SW. Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos. Circ Res. 2014 Jan 3;114(1):56-66. doi: 10.1161/CIRCRESAHA.114.302452. Epub 2013 Oct 11. |
Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia
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Citation:
Am J Hum Genet. 2013 Dec 5;93(6):1126-34. doi: 10.1016/j.ajhg.2013.10.028. Epub 2013 Nov 27. Review Epub:
Not Epub Abstract:
The strictly regulated expression of most pleiotropic developmental control genes is critically dependent on the activity of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bhatia S, Bengani H, Fish M, Brown A, Divizia MT, de Marco R, Damante G, Grainger R, van Heyningen V, Kleinjan DA. Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia. Am J Hum Genet. 2013 Dec 5;93(6):1126-34. doi: 10.1016/j.ajhg.2013.10.028. Epub 2013 Nov 27. Review. |
Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment
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Citation:
J Drug Target. 2013 Dec;21(10):956-67. doi: 10.3109/1061186X.2013.837470. Epub 2013 Sep 16 Epub:
Not Epub Abstract:
Engineered nanoparticles are widely used for delivery of drugs but frequently lack proof of safety for cancer patient's... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Ljubimova JY, Portilla-Arias J, Patil R, Ding H, Inoue S, Markman JL, Rekechenetskiy A, Konda B, Gangalum PR, Chesnokova A, Ljubimov AV, Black KL, Holler E. Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment. J Drug Target. 2013 Dec;21(10):956-67. doi: 10.3109/1061186X.2013.837470. Epub 2013 Sep 16. |
Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate
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Citation:
Biol Open. 2014 Mar 15;3(3):192-203. doi: 10.1242/bio.20147401 Epub:
Not Epub Abstract:
We previously found that the small GTPase Ras-dva1 is essential for the telencephalic development in Xenopus laevis because Ras... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Tereshina MB, Ermakova GV, Ivanova AS, Zaraisky AG. Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate. Biol Open. 2014 Mar 15;3(3):192-203. doi: 10.1242/bio.20147401. |
Zebrafish churchill regulates developmental gene expression and cell migration
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Citation:
Dev Dyn. 2013 Jun;242(6):614-21. doi: 10.1002/dvdy.23958. Epub 2013 Mar 29 Epub:
Not Epub Abstract:
BACKGROUND: Regulation of developmental signaling pathways is essential for embryogenesis. The small putative zinc finger... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Taibi A, Mandavawala KP, Noel J, Okoye EV, Milano CR, Martin BL, Sirotkin HI. Zebrafish churchill regulates developmental gene expression and cell migration. Dev Dyn. 2013 Jun;242(6):614-21. doi: 10.1002/dvdy.23958. Epub 2013 Mar 29. |
Tbx2/3 is an essential mediator within the Brachyury gene network during Ciona notochord development
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Citation:
Development. 2013 Jun;140(11):2422-33. doi: 10.1242/dev.094227 Epub:
Not Epub Abstract:
T-box genes are potent regulators of mesoderm development in many metazoans. In chordate embryos, the T-box transcription... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis Citation Extract: José-Edwards DS, Oda-Ishii I, Nibu Y, Di Gregorio A. Tbx2/3 is an essential mediator within the Brachyury gene network during Ciona notochord development. Development. 2013 Jun;140(11):2422-33. doi: 10.1242/dev.094227. |
Tcf21 regulates the specification and maturation of proepicardial cells
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Citation:
Development. 2013 Jun;140(11):2409-21. doi: 10.1242/dev.093385. Epub 2013 May 1 Epub:
Not Epub Abstract:
The epicardium is a mesothelial cell layer essential for vertebrate heart development and pertinent for cardiac repair post-... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Tandon P, Miteva YV, Kuchenbrod LM, Cristea IM, Conlon FL. Tcf21 regulates the specification and maturation of proepicardial cells. Development. 2013 Jun;140(11):2409-21. doi: 10.1242/dev.093385. Epub 2013 May 1. |
Xenopus Dead end mRNA is a localized maternal determinant that serves a conserved function in germ cell development
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Citation:
Dev Biol. 2006 Mar 1;291(1):1-11. Epub 2006 Jan 30 Epub:
Not Epub Abstract:
Germ plasm formation is considered to define the first step in germ cell development. Xenopus Dead end represents a germ plasm... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Horvay K, Claussen M, Katzer M, Landgrebe J, Pieler T. Xenopus Dead end mRNA is a localized maternal determinant that serves a conserved function in germ cell development. Dev Biol. 2006 Mar 1;291(1):1-11. Epub 2006 Jan 30. |